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DU PA-DM
Duke PA Diabetes Mellitus
| Question | Answer |
|---|---|
| polydipsia | excessive thirst |
| polyuria | excessive urination |
| early sign of type II DM | nocturia |
| Type II DM has a strong __ | genetic predisposition |
| two things to check each time a diabetic visits the office | blood pressure and feet |
| least common type of diabetes | type 1 |
| __% of diabetics are type I | 5-10 |
| __% of diabetics are type II | 90-95 |
| type I diabetes is caused by __ destruction | beta cell |
| __ can destroy beta cells | pancreatitis or autoimmunity |
| most common type of diabetes | type II |
| patients with __ diabetics have insulin resistance | type II |
| formerly called juvenile onset diabetes | type I |
| formerly called adult onset diabetes | type II |
| women with gestational diabetes can have | big babies |
| women with gestational diabetes have a __% chance of developing type II diabetes | 50 |
| Habitual physical inactivity | lazy |
| diabetes risk factors age greater than __ | 45 |
| women with polycystic ovary syndrome have increased __ | androgen levels |
| HDL < or = __mg/dl is a diabetes risk factor | 35 |
| triglycerides > or = __ is a diabetes risk factor | 250 |
| __ ovary syndrome is a diabetes risk factor | polycystic |
| FPG > or = 126 mg/dl | diabetes |
| FPG <126 mg/dl but > or = 110mg/dl | pre-diabetes |
| FPG < 110 mg/dl | normal |
| complications of diabetes | stroke, retinopathy, end stage renal disease, heart disease, foot/leg amputation |
| screen for end stage renal disease with | microalbumin |
| Measures Glucose Levels over 2-3 Month Period | HbA1c |
| Cannont be used to diagnose diabetes | HbA1c |
| don't order an HbA1c after a | cardiac bypass |
| HbA1c will not be accurate in patients with | sickle cell disease, hemolytic anemia, certain drugs, recent trasnfusion |
| suggested glucose range for diabetics before meals __mg/dL | 80-120 |
| suggested glucose range for diabetics after meals __mg/dL | 100-180 |
| suggested glucose range for diabetics at bedtime __mg/dL | 100-140 |
| suggested A1c for people with diabetes __% | 7 |
| the only current drug used to treat type I diabetes | insulin |
| 2 problems of type II diabetes | lack of correct glucose secretion, insulin resistance |
| best treatment for type II diabetes | lifestyle modification |
| ADA target A1c <__% | 7 |
| target bp for diabetics | 130/80 |
| target LDL for diabetics < or = __mg/dL | 100 |
| target HDL for diabetics > __ mg/dL | 35-45 |
| regular insulin is | clear |
| NPH insulin is | cloudy |
| in diabetes get rid of the __ first | low sugars |
| we don't use __ insulin treatment anymore | sliding scale |
| if you use a sliding scale insulin treatment you will let the patient get __ | sweet (hyperglycemic) |
| diabetic ketoacidosis occurs in type __ predominantly | I |
| diabetic ketoacidosis can occur in poorly controlled type __ diabetes | II |
| diabetic ketoacidosis breathing | Kussmaul breathing |
| reasons for DKA | infection, cardiac event, skipped medication |
| what can happen if you overreplace fluid in a child with DKA | cerebral edema |
| in euglycemia DKA | treat the acid not the sugar |
| when shutting off the insulin pump first give a __ | bolus of long acting insulin |
| enteral hypoglycemia treatment | 15 gm of carbohydrates |
| 15 grams of carbohydrates = | 3 glucotabs, 1/2 cup OJ, 5 lifesavers, 1/2 cup regular soda |
| parenteral hypoglycemia treatment | D50 IV, glucagon 1 mg IM |
| complications of diabetes | atherosclerotic vascular disease, renal disease, neuropathy, retinopathy |
| FBS of 126 mg/dL is roughly equivalent to an A1c of __% | 7 |
| FBS of 126 mg/dL is roughly equivalent to a 2 hour GTT of __ mg/dL | 200 |
| created when proinsulin splits into insulin and C-peptide | connecting peptide |
| c-peptide is decreased in __ diabetes | type I |
| c-peptide is increased or normal in __ diabetes | type II |
| Fasting blood glucose: no caloric intake for at least __ hours | 8 |
| Timed blood draw after oral load of a specific amount of glucose | Oral glucose tolerance testing (OGTT or GTT) |
| medications that increase glucose | diuretics, estrogens, beta blockers, corticosteroids |
| medications that decrease glucose | acetaminophen, alcohol, propanolol, anabolic steroids |
| 3 hour GTT Interpretation-normal fasting < __ mg/dL | 95 |
| 3 hour GTT Interpretation-normal 1 hour < __ mg/dL | 180 |
| 3 hour GTT Interpretation-normal 2 hour < __ mg/dL | 155 |
| 3 hour GTT Interpretation-normal 3 hour < __ mg/dL | 140 |
| abnormal 3 hour GTT Interpretation is defined as | 2 or more values above reference range |
| In normal people, 3-6% of hemoglobin is glycosylated in the form __ | A1c |
| gives information about long term glycemic control(previous 8-12 weeks) | HbA1c |
| patients with episodic or chronic hemolysis who have larger proportion of young RBCs might have spuriously low levels of | HbA1c |
| glycated albumin or glycated serum protein | fructosamine |
| Reflects hyperglycemic period within the last few weeks | fructosamine |
| Gives information of short term glycemic control | fructosamine |
| Useful for patients with chronic hemolytic anemias that cause shortened RBC life span | fructosamine |
| urine microalbumin | nephropathy |
| most common complication of DM | neuropathy |
| these are painless due to peripheral neuropathy | diabetic foot ulcer |
| 1 out of __ Americans born in the United states in 2000 are at risk for DM | 3 |
| Caused by destruction of insulin producing cells | Type I DM |
| Diabetes develops during pregnancy and resolves after pregnancy | gestational diabetes |