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terms
| Term | Definition |
|---|---|
| Codis | “Combined DNA Index System” (CODIS) is the generic term used to describe the FBI’s program of support for criminal justice DNA databases as well as the software used to run these databases. |
| RFLP | a variation in the length of restriction fragments produced by a given restriction enzyme in a sample of DNA. Such variation is used in forensic investigations and to map hereditary disease. |
| Sticky Ends | an end of a DNA double helix at which a few unpaired nucleotides of one strand extend beyond the other. |
| DNA fingerprints | the analysis of DNA from samples of body tissues or fluids in order to identify individuals. |
| Cleave | split or sever something |
| DNA | deoxyribonucleic acid, a self-replicating material present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information. |
| Comb | prepare (wool, flax, or cotton) for manufacture with a comb. |
| Restriction Enzyme | an enzyme produced chiefly by certain bacteria, having the property of cleaving DNA molecules at or near a specific sequence of bases. |
| Exclusion | the process or state of excluding or being excluded. |
| Hybridzation | the act of mixing different species or varieties of animals or plants and thus to produce hybrids |
| VNTR | A Variable Number Tandem Repeat is a location in a genome where a short nucleotide sequence is organized as a tandem repeat. These can be found on many chromosomes, and often show variations in length between individuals. |
| Nucleotides | a compound consisting of a nucleoside linked to a phosphate group. Nucleotides form the basic structural unit of nucleic acids such as DNA. |
| Gel lanes | Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge. |
| DNA fragments | DNA fragments are pieces of the hereditary material used in a process known as sequencing. |
| Palindrome | A palindromic sequence is a nucleic acid sequence (DNA or RNA) that is the same whether read 5' (five-prime) to 3' (three prime) on one strand or 5' to 3' on the complementary strand with which it forms a double helix |
| Wells | The lower part of a furnace, into which the metal falls. Artesian well, Driven well. See Artesian, and Driven. Pump well. |
| STR | Short Tandem Repeat ...A pattern in DNA where two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other, used in determining genetic profiles to identify an individual. |
| Electric Field | a region around a charged particle or object within which a force would be exerted on other charged particles or objects. |
| Inclusion | a body or particle recognizably distinct from the substance in which it is embedded. |
| Microliter | one millionth of a liter. |
| Human Genome | The human genome is the complete set of genetic information for humans |
| Blunt cut | straight cut |
| Buffer | a solution that resists changes in pH when acid or alkali is added to it. Buffers typically involve a weak acid or alkali together with one of its salts. |
| Recombinant DNA | DNA that has been formed artificially by combining constituents from different organisms. |
| DNA polymerase | the enzyme responsible for DNA replication |
| Gene | a unit of heredity that is transferred from a parent to offspring and is held to determine some characteristic of the offspring |
| Digital Micropipet | pipette designed for the measurement of very small volumes. |
| Staggered cut | the cleavage of two opposite strands of duplex DNA at points near one another. |
| Agarose gel | Agarose gel electrophoresis is a method of gel electrophoresis used in biochemistry, molecular biology, and clinical chemistry to separate a mixed population of DNA or proteins in a matrix of agarose. |
| Inconlusive | not leading to a firm conclusion; not ending doubt or dispute. |
| Fingerprint | an impression or mark made on a surface by a person's fingertip, esp. as used for identifying individuals from the unique pattern of whorls and lines |
| Luminol | Luminol is a versatile chemical that exhibits chemiluminescence, with a striking blue glow, when mixed with an appropriate oxidizing agent |
| PCR | Phosphocreatine, also known as creatine phosphate or PCr, is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and the brain. |
| Restriction site | The site in a polynucleotide chain as to where the restriction enzyme cleaves nucleotides by hydrolyzing the phosphodiester bond between them. |
| Gel Electrophoresis | Gel electrophoresis is a method for separation and analysis of macromolecules and their fragments, based on their size and charge. |
| Evindence | the available body of facts or information indicating whether a belief or proposition is true or valid. |