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VTNE Pharmacology

Pharmacology questions from my VTNE app

When discussing drug interactions what is the term used to describe a drug that mimics a natural body substance or normal function when interacting with a receptor? An agonistic drug
When discussing drug interactions what is the term used to describe a drug that blocks a natural body substance or normal function without producing any physiological effect? an antagonist drug
In which organ does the detoxification of drugs and toxins normally occur? Liver
The excretion of drugs can occur in the-- kidneys, bowel, and lungs
what is the concern when administering injectable medications intramuscularly? injection into blood vessel or nerve fiber
The perivascular injection of caustic drugs is a risk associated with: Intravenous injections
A cholinergic agent is one that mimics the stimulatory acetylcholine effects
when calculating dosages, each patient should be dosed to: effect
Into what form(s) can a drug solution be formulated? syrup, elixir, and tinctures
Which is the amount of drug given per unit of body weight? dosage
Convert a 45 pound dog's weight into kilograms 20 kg (2.2 lbs/kg)
What is the term for drugs that kill or inhibit the growth of other microorganisms? Antimicrobials
Sally is about to premedicate a surgical patient with 0.011mg/kg of glycopyrrolate. What reason(s) do she and the veterinarian have for using this drug? Increase heart rate, dry secretions, and long duration of action
Sally as used the following anesthetic plan for a feline orchiectomy: acepromazine, glycopyrrolate, and ketamine. Her patient is suffering form catalepsy following induction. Which medication(s) caused this condition? Ketamine
Sally is preparing to induce a pt using propofol. She has a patent iv cath placed in the right cephalic vein, and has checked her anesthesia machine and ET tube for leaks. What is her initial concern when administering propofol? Apnea
A patient is prescribed a medication the the instructions to apply is O.S. p.i.d. x 10 days. What does this mean? Apply to the left eye, four times daily, for ten days
In order for a patient to benefit from drug therapy, the body must absorb the medication. What are the primary routes of drug absorption? Across cellular membranes, GI tract, topical, tracheobronchial surfaces, and alveoli, and parenteral
How does bioavailability relate significantly to drugs administered by mouth and absorbed through the GI tract? Intestinal epithelial cells and the liver can reduce the amount of unchanged drug that enters the circulation system.
Toxicity can occur from drugs that require elimination through urinary excrement in patients with which of the following conditions? Renal failure
If a medication is administered to an unhealthy patient whose drug clearance ability is reduced by 50%, what effect will this have on the half-life of the drug? The half-life will double. When a patient's clearance capability is reduced, eliminnation of the drug is slowed, thereby increasing the half-life.
An 11.5 pound toy poodle is prescribed Ketoconazole at a recommended dose rate of 10 mg/kg, PO, bid. If the Ketoconazole tablets are 100mg each, how many milligrams (rounded up or down to the nearest whole number) would this dog need and how often? 50 mg twice daily
What type of drugs, when given by mouth, will interfere with the GI absorption of concurrently administered drugs such as digoxin or tetracycline? Antacids
Created by: slindsey137