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VirologyFamiles
| Question | Answer |
|---|---|
| Largest and most complex virus | pox |
| shape of pox | brick |
| shape of parapox | ovoid |
| structure of virions in pox (cubic, helical or complex) | complex |
| shape of core of pox | dumbbell, barbell or peanut |
| envelope present? | may or may not be |
| genome of pox | linear dsDNA |
| stable or not | stable |
| where does replication occur? | cytoplasm |
| inclusion bodies? | yes (eosinophilic intracytoplasmic inclusions) |
| genetic recombination between other genre? | no |
| genetic recombination between genre? | yes, results in extensive serological cross-reaction and cross-protection |
| hemogglutinin produced? | only by orthopox |
| all pox share group-specific nucleoprotein antigen which is exposed following alkaline digestion. true or false | true |
| chordopox | pox of vertebrates |
| orthopox | vaccinia |
| parapox | pseudocowpox |
| avipox | fowlpox |
| capripox | sheeppox |
| lepropox | leporipox |
| suipox | swinepox |
| molluscipox | myoxoma virus |
| yabapox | yaba monkey tumor virus |
| entomopox | viruses of insects |
| where does viral replication of pox virus happen | cytoplasm |
| name the family: adsorption and penetration (endocytosis for nonenveloped and fusion for enveloped) is followed by the release of the viral core into the cytoplasm | pox |
| true or false. encoding is a three step process for pox | false. two |
| name the family. host cell enzymes partially uncoat the viral particle which exposes some viral DNA and polymerase | pox |
| most pox are enveloped or nonenveloped | not enveloped |
| true or false. only enveloped pox are are infectious | false, both are infectious |
| pox release out of the cell how | budding,exocytosis (enveloped) and cell lysis (non enveloped) |
| pox--resistant or not | resistant--can survive for many months or years in dried scabs |
| pox transmitted how | induction into small skin abrasions aerosol of resp. tract mechanical transmission by biting arthropods (no biological transmission) |
| pox are highly epitheliotropic true or false | true |