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Path 12

Vagina, Vulva, and Cervix

What lines the ectocervix non-keratinizing stratified squamous epithelium
What lines the endocervix mucin secreting, simple columnar epithelium
What is the squamocolumnar junction the area between the endocervical epithelium and the ectocervical squamous cells
What is the area where cells undergo metaplasia squamocolumnar junction (the area of metaplasia is where dysplasia occurs)
What is the transformation zone area between the original squamocolumnar junction and the new squamocolumnar junction (junction position changes depending on hormonal status)
what are the low risk HPVs 6 and 11
What are the high risk HPVs 16, 18, 31, 33
What are risk factors for HPV infection early age of first sexual intercourse, numerous sexual partners, smoking
What is the most common sexually transmitted disease in the Western hemisphere Chlamydia trachomatis
What are some complications of Chlamydia endometritis and salpingitis; postinfectious inclues Pelvic inflammatory disease, tubal infertility, neonatal pneumonia
What are the physical manifestations of HSV 2 virus vesicles (nonpainful) and shallow ulcerations (excruciatingly painful)
What would you suspect if you saw white changes of the vulva with parchment paper like look in a post menopausal woman? lichen sclerosis et atrophicus
Is Lichen sclerosis et atrophicus related to HPV? no
What would you suspect if you saw a red and eczematous lesion with irregular boders in an older postmenopausal woman Padget disease
Who gets vaginal clear cell carcinoma adolescents
Female children of women who used DES during their pregnancy are at increased risk for ? vaginal carcinoma Clear Cell Carcinoma
What is the subtype of embryonal rhabdomyosarcoma that is often found in cavities such as the vagina and the bladder (Grape-like) Sarcoma Botryoides
What is a common presentating symptom of an endocervical polyp post coital bleeding
The endometrium of the uterus is composed of? glands (lined by simple columnar epithelial cells) and surrounding stroma
The myometrium is composed of? smooth muscle and vessels and lymphatics
Virtually all physiologic and pathologic lesions of the endometrium can present with? abnormal vaginal bleeding
Estrogen is responsible for what endometrial phase? Progesterone? estrogen-proliferative progesterone-secretory
When do you often see acute endometiritis postpartum or postabortal period
What is Adenomyosis endometrial glands and stroma within the myometrium.
What is the cause of endometrial hyperplasia increased estrogen
What are the risk factors for endometrial adenocarcinoma obesity, nulliparity, late menopause, chronic anovulation, unopposed estrogen replacement therapy, tamoxifen therapy
Are most patients pre or post menopausal at the time of presentation with endometrial adenocarcinoma 75% are post menopausal
What are the two main types of endometrial adenocarcinoma Endometrioid and Uterine Papillary Serous Carcinoma
What is the most common type of Endometrial adenocarcinoma endometrioid
Does endometrioid or Uterine papillary serous carcinoma usually occur in the setting of atrophy? Uterine papillary serous carcinoma
What is the most common neoplasm in women leiomyomas
what is the characteristic gross appearance of leiomyomas well-cercumscribed, spherical mass, dense whorled, tan-white
How does a Leiomyosarcoma appear grossly foci of hemorrhage and necrosis
What is the histological appearance of leiomyosarcomas cytologic atypia with mitotic activity and necrosis
When an elderly woman presents with a polypoid mass arisin in the endometrium but protruding through the cervical canal may have? Malignant mixed mullerian tumors
What is the Chromosome pattern seen in a complete hydatidiform mole? 46XX or 46XY
What do hydatidiform moles secrete? B-HCG
Created by: UVAPATH1



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