Path 12 Word Scramble
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Question | Answer |
What lines the ectocervix | non-keratinizing stratified squamous epithelium |
What lines the endocervix | mucin secreting, simple columnar epithelium |
What is the squamocolumnar junction | the area between the endocervical epithelium and the ectocervical squamous cells |
What is the area where cells undergo metaplasia | squamocolumnar junction (the area of metaplasia is where dysplasia occurs) |
What is the transformation zone | area between the original squamocolumnar junction and the new squamocolumnar junction (junction position changes depending on hormonal status) |
what are the low risk HPVs | 6 and 11 |
What are the high risk HPVs | 16, 18, 31, 33 |
What are risk factors for HPV infection | early age of first sexual intercourse, numerous sexual partners, smoking |
What is the most common sexually transmitted disease in the Western hemisphere | Chlamydia trachomatis |
What are some complications of Chlamydia | endometritis and salpingitis; postinfectious inclues Pelvic inflammatory disease, tubal infertility, neonatal pneumonia |
What are the physical manifestations of HSV 2 virus | vesicles (nonpainful) and shallow ulcerations (excruciatingly painful) |
What would you suspect if you saw white changes of the vulva with parchment paper like look in a post menopausal woman? | lichen sclerosis et atrophicus |
Is Lichen sclerosis et atrophicus related to HPV? | no |
What would you suspect if you saw a red and eczematous lesion with irregular boders in an older postmenopausal woman | Padget disease |
Who gets vaginal clear cell carcinoma | adolescents |
Female children of women who used DES during their pregnancy are at increased risk for ? vaginal carcinoma | Clear Cell Carcinoma |
What is the subtype of embryonal rhabdomyosarcoma that is often found in cavities such as the vagina and the bladder (Grape-like) | Sarcoma Botryoides |
What is a common presentating symptom of an endocervical polyp | post coital bleeding |
The endometrium of the uterus is composed of? | glands (lined by simple columnar epithelial cells) and surrounding stroma |
The myometrium is composed of? | smooth muscle and vessels and lymphatics |
Virtually all physiologic and pathologic lesions of the endometrium can present with? | abnormal vaginal bleeding |
Estrogen is responsible for what endometrial phase? Progesterone? | estrogen-proliferative progesterone-secretory |
When do you often see acute endometiritis | postpartum or postabortal period |
What is Adenomyosis | endometrial glands and stroma within the myometrium. |
What is the cause of endometrial hyperplasia | increased estrogen |
What are the risk factors for endometrial adenocarcinoma | obesity, nulliparity, late menopause, chronic anovulation, unopposed estrogen replacement therapy, tamoxifen therapy |
Are most patients pre or post menopausal at the time of presentation with endometrial adenocarcinoma | 75% are post menopausal |
What are the two main types of endometrial adenocarcinoma | Endometrioid and Uterine Papillary Serous Carcinoma |
What is the most common type of Endometrial adenocarcinoma | endometrioid |
Does endometrioid or Uterine papillary serous carcinoma usually occur in the setting of atrophy? | Uterine papillary serous carcinoma |
What is the most common neoplasm in women | leiomyomas |
what is the characteristic gross appearance of leiomyomas | well-cercumscribed, spherical mass, dense whorled, tan-white |
How does a Leiomyosarcoma appear grossly | foci of hemorrhage and necrosis |
What is the histological appearance of leiomyosarcomas | cytologic atypia with mitotic activity and necrosis |
When an elderly woman presents with a polypoid mass arisin in the endometrium but protruding through the cervical canal may have? | Malignant mixed mullerian tumors |
What is the Chromosome pattern seen in a complete hydatidiform mole? | 46XX or 46XY |
What do hydatidiform moles secrete? | B-HCG |
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