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surgery & anesthesia

injectable anesthetics

what are the 3 type of injectable anesthetics? Barbiturates, propofol, and etomidate
injectable anesthetics don't do what? Don’t provide analgesia or muscle relaxation
can injectable anesthetics be used with other agents? YES.
Barbiturates are a derivative of __________. barbituric acid
Barbiturates are controlled or non-controlled? CONTROLED.
What are the subclasses of barbiturates based on duration? ultra-short, short, intermediate, & long-acting
3 ultra-short barbiturates: Thiopental sodium, methohexital, and thiamylal
what species is ultra-short barbiturates used on? cats, dogs, & horses
what do ultra-short barbiturates do? induce general anesthesia
a short acting barbiturate: Pentobarbital
what is a benefit of pentobarbital? can treat epilepsy
short acting barbiturates do what? induce general anesthesia
an intermediate barbiturate: Secanol, treats tetanus & epilespy
a long acting barbiturate is: phenobarbital
the 2 subclasses based on chemical structure: OXYBARBITURATES (Phenobarbital, pentobarbital, & methohexital) & THIOBARBITURATES (Thiopental and thiamylal)
Action of barbiturates: Mimics the inhibitory neurotransmitter GABA --> Depresses nerve impulses to cerebral cortex --> CNS depression --> loss of consciousness
Ionization: Is in both polar (ionized) & nonpolar (nonionized) forms
Nonpolar (nonionized) forms can: pass through the cell membrane
Increased nonpolarization, increased drug amounts to brain, exaggerated patient response, lower dose to anesthetize an animal are an indication of what? Acidosis (blood pH <7.4)
c/s of metabolic acidosis: diarrhea, ketosis, severe infection, admin. Of acidic drugs (cholorphenicol & aminoglycosides) , shock! Increased resp.
c/s of metabolic alkalosis: vomiting, corticosteroid overdose, decreased resp.
Resp. Acidosis = hypoventilation
Retention CO2 = hypercapnia
Created by: eflores917