GlycogenStoreDisease Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Disease | Defect, Effect |
Type 1 (Von Gierke) | lack of G-6-Phosphatase present in only kidney & liver;accumulation of G-6-P & G-1-P,cant become glucose-also cant become glucose from gluconeogenesis & G-1-P inhibits glycogen phosphorylase = further hypoglycemia w/ hepatorenomegaly |
Type 2 (Pompe) | lack of alpha-glycosidase;accumulation of glycogen & no glucose nor G-1-P causes hepatocardiomegaly also death by age 2,also affects other organs |
Type 3 (Cori's) | lack of debranching enzyme;accumulation of branched glycogen that results in hepatomegaly |
Type 4 (McArdle) | lack of skeletal muscle phosphorylase;results in accumulation of glycogen in skeletal muscle causing muscle pain & cramps w/ no rise in lactate = starvation w/ no glucose for glycolysis,progress to muscle weakness despite glycogen content |
Created by:
jerrica_08
Popular Medical sets