Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Remove Ads
Don't know
remaining cards
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards

Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


USMLE Step 1 - Biochem

DiseaseDefect, Effect
Type 1 (Von Gierke) lack of G-6-Phosphatase present in only kidney & liver;accumulation of G-6-P & G-1-P,cant become glucose-also cant become glucose from gluconeogenesis & G-1-P inhibits glycogen phosphorylase = further hypoglycemia w/ hepatorenomegaly
Type 2 (Pompe) lack of alpha-glycosidase;accumulation of glycogen & no glucose nor G-1-P causes hepatocardiomegaly also death by age 2,also affects other organs
Type 3 (Cori's) lack of debranching enzyme;accumulation of branched glycogen that results in hepatomegaly
Type 4 (McArdle) lack of skeletal muscle phosphorylase;results in accumulation of glycogen in skeletal muscle causing muscle pain & cramps w/ no rise in lactate = starvation w/ no glucose for glycolysis,progress to muscle weakness despite glycogen content
Created by: jerrica_08