cytokines Word Scramble
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cytokine | source and action |
TGF-beta | T, B, Mf -> inh T's, neg. regulator, + collagen |
alpha chemokines- C-X-C | monos-> attracts neutrophils (IL-8) |
beta chemokines- C-C | T's -> attracts monocytes (RANTES, MCAF) |
TNF- alpha | mf -> infl, endotoxin- induced septic shock; cachectin (inh LPL); necrosis of tumor cells |
TNF- beta | T cells-> aka lymphotoxin; similar to TNF-a |
NO | mf-> induced by LPS --> vasodilation |
MIF | mf-> induced by LPS -> septic shock |
IFN-g | Th1-> potent activator of mf, NK, neutrophil phagocytosis |
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