Block 3 Drugs
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| Cimetidine trade name | Tagamet
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| Cimetidine class | H2 antag
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| Ranitidine trade name | Zantac
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| Ranitidine class | H2 antag
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| Famotidine trade name | Pepcid
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| Famotidine class | H2 antag
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| Omeprazole trade name | Prilosec
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| Omeprazole class | Proton pump inhibitor
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| Metronidazole class | Nitroimidazol antibiotic
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| Amoxicillin class | Penicillin antibiotic
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| Clarithomycin class | Macrolide antibiotic
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| AlOH3 and MgOH2 trade name | Mylanta, Maalox
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| Mylanta, Maalox class | Antacid Salt
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| Calcium Carbonate trade name | Tums
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| Tums class | Antacid Salt
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| Sodium Bicarbonate trade name | Alka Seltzer
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| Alka Seltzer class | Antacid Salt
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| Sucralfate trade name | Carafate
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| Sucralfate class | Mucosal protective agent
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| Misoprostol trade name | Cytotec
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| Misoprostol class | Mucosal Protective Agent
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| Bismuth Subasalicylate trade name | Pepto Bismol
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| Bismuth Subsalicylate class | Mucosal Protective Agent
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| Metoclopramide trade name | Reglan
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| Metoclopramide class | Prokinetic Agent
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| Cimetadine Adverse | blocks P450s
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| Famotidine Advantage | does not inhibit first pass ethanol metabolism
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| Proton Pump Inhibitor MOA | covalent modification of H/K ATPase- irreversible
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| Zollinger-Ellison treatment of choice | Proton Pump Inhibitors
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| Sucralfate MOA | produces protective covering of ulceration
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| Misoprostol MOA | Prostaglandin receptor agonist- inc. secretion of mucous and bicarb
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| Misoprostol Adverse | causes myometrial contrxn- no use in pregnancy
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| Metoclopramide MOA | 5-HT4 receptor agonist- gastric emptying
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| Ciprofloxacin trade name | Cipro
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| Ciprofloxacin class | Fluorinated 4-quinolone
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| Ofloxacin trade name | Floxin
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| Ofloxacin class | Fluorinated 4-quinolone
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| Norfloxacin class | Fluorinated 4-quinolone
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| Octreotide trade name | Sandostatin
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| Octreotide class | Somatostatin analog
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| Diphenoxylate trade name | Lomotil
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| Diphenoxylate class | Piperidine opioid mu agonist
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| Difenoxin trade name | Motofen
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| Difenoxin class | Piperidine opioid mu agonist
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| Loperamide trade name | Imodium
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| Loperamide class | Piperidine opioid mu agonist
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| Ondensatron trade name | Zofran
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| Ondensatron class | 5-HT3 Antagonist
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| Granisetron trade name | Kytril
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| Granisetron class | 5-HT3 Antagonist
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| Trimethobenzamide trade name | Tigan
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| Trimethobenzamide class | D2 antagonist- prokinetic agent
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| Chlorpromazine trade name | Thorazine
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| Chlorpromazine class | Neuroleptic
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| Prochlorperazine trade name | Compazine
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| Prochlorperazine class | Neuroleptic
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| Heloperidol trade name | Haldol
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| Heloperidol class | Neuroleptic
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| Dexamethasone class | Glucocorticoid
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| Dronabinol trade name | Marinol (pot)
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| Dronabinol class | Cannabinoid
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| Lorazepam trade name | Ativan
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| Lorazepam class | Benzodiazepines
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| Promethazine class | Antihistamine
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| Scopolamine class | Anticholinergic
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| Ipecac | Emetic
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| Opioid MOA | Reduced motility, acid- antidiarrheal
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| Fluorinated 4- quinolones MOA | Inhibit A subunit of DNA gyrase
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| Bismuth salicylate MOA | coating ulceration (dyspepsia), antimicrobial(ulcers and diarrhea)
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| mu opioid agonists MOA | inhib of presynaptic nerves of myenteric plexus- low motility
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| Difenoxylate, Difenoxin Adverse | Affect CNA- can be addictive
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| Octreotide MOA | Interaction with somatostatin receptor
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| Octreotide Adverse | gallstones due to decreased emptying
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| 5-HT3 receptor antagonists MOA | block 5-HT3 receptor- anti-emetics
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| Metoclopramide anti-emetic MOA | 5-HT3 agonist, D2 antag- inc. motility
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| Dexamethasone MOA | decrease inflammation- anti-emetic
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| Dronabinol MOA | Cannabinoid agonist- anti-emetic
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| Promethazine, Diphenylhydramine MOA | H1 receptor antagonists- motion sickness and vertigo
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| Scopolamine MOA | Muscarinic antagonist- motion sickness
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| Apomorphine class | pro-emetic (poisoning)- stimulates the CTZ
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| Diuretics | Compounds that produce salt excretion
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| Diuretic uses | CHF, Hypertension, Edema
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| Acetazolamide trade name | Diamox
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| Acetazolamide class | CA inhibitor
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| Dichlorophenamide trade name | Daranide
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| Dichlorophenamide class | CA inhibitor
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| Methazolamide trade name | Neptazane
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| Methazolamide class | CA inhibitor
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| CA inhibitor uses | Glaucoma, Cerebral Edema, Alkalosis
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| CA inhibitor MOA | dec. reabs. of bicarb
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| Glycerin class | Osmotic Diuretic
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| Isosorbide class | Osmotic Diuretic
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| Mannitol class | Osmotic Diuretic
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| Urea class | Osmotic Diuretic
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| Osmotic Diuretic MOA | osmotically keep water in tubule- excretion
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| Ethacrynic Acid trade name | Edecrin
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| Ethacrynic Acid class | Loop Diuretic
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| Furosemide trade name | Lasix
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| Furosemide class | Loop Diuretic
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| Bumetanide trade name | Bumex
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| Bumetanide class | Loop Diuretic
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| Torsemide trade name | Demadex
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| Torsemide class | Loop Diuretic
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| Loop Diuretic MOA | look up!
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| Loop Diuretic secretion | not filtered- secreted in prox tubule
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| Loop Diuretic adverse | K+ wasting, hyponatremia
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| Chlorothiazide trade name | Diuril
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| Chlorothiazide class | Thiazide diuretic
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| Hydrochlorothiazide trade name | Hydrodiuril
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| Hydrochlorothiazide class | Thiazide diuretic
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| Thiazide MOA | Inhib NaCl symport in dist tubule
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| Thiazide adverse | tolerance after 1 wk, lethal with Quinidine (antiarrhythmetic)
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| Amiloride trade name | Midamor
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| Triamterene trade name | Dyrenium, Maxide
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| Amiloride class | Na+ channel inhibitor
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| Triamterene class | Na+ channel inhibitor
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| Na+ channel inhib advantage | K+ sparing
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| Na+ channel inhib MOA | Inhib Na+ channel in dist tubule
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| Spironolactone trade name | Aldactone
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| Spironolactone class | Aldosterone Antagonist
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| Aldosterone Antagonist MOA | Prevents ALDO-MR binding, dec. Na+ reabs and K+ secretion
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| T. enanthate, cypionate, propionate | IM Testosterone replacements
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| Testoderm | Transcrotal Testosterone replacement
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| Androderm | Transdermal Testosterone replacement patch
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| Androgel | Transdermal Testosterone replacement gel
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| Testopel | subQ implant testosterone replacement
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| Sildenafil trade name | Viagra
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| Sildenafil MOA | PDE 5 inhibitor- inc. cGMP, vasodilation
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| Sildenafil use | Tx. of ED
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| Vardenafil trade name | Levitra
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| Vardenafil MOA | PDE 5 inhibitor- inc. cGMP, vasodilation
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| Vardenafil use | Tx. of ED
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| Tadalafil trade name | Cialis
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| Tadalafil MOA | PDE 5 inhibitor- inc. cGMP, vasodilation
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| Tadalafil use | Tx. ED
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| Yohimbine class | a2 adrenergic antagonist
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| Yohimbine use | Tx. psychogenic ED
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| Papaverine | opioid peptide
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| Papaverine | injected tx. for ED
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| Phentolamine | alpha adrenergic antag
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| Phentolamine | injected tx. for ED
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| Alprostadil class | PGE1
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| Alprostadil admin route | penile injection or urethral pellet
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| Alprostadil use | Tx. ED
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