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Language of Medicine Chapter 19 - Created by MTatHome.com

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Answer
adenocarcinoma   Cancerous tumor of glandular tissue.  
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adjuvant therapy   Treatment of disease with substances that assist or enhance the action of primary treatment.  
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alkylating agents   Synthetic chemicals used in treatment of cancer. They interfere with DNA synthesis and cell division to prevent cancer cells from increasing in number.  
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alopecia   Partial or complete lack of hair.  
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alveolar   Pertaining to a small sac or alveolus.  
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anaplasia   Loss of differentiation of cells and reversion to a more primitive, unspecialized cell type.  
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angiogenesis   Process of forming new blood vessels.  
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antibiotics   Chemical substance produced by bacteria or primitive plants; inhibit the growth of cells and are used in treatment of cancer and infectious disease.  
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antimetabolites   Chemicals that prevent cell division by inhibiting formation of substances necessary to make DNA; used in cancer treatment.  
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antimitotics   Drugs that block mitosis (cell division); used to treat cancer.  
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apoptosis   Programmed cell death.  
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benign tumor   Noncancerous growth.  
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biologic response modifiers   Substances produced by normal cells that block tumor growth or stimulate the immune system to fight cancer.  
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biologic therapy   Use of body’s own defenses to fight tumor cells.  
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bone marrow biopsy   Small amount of bone marrow tissue is removed (aspirated) and examined under a microscope for evidence of malignancy.  
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bone marrow transplant   Bone marrow tissue is infused intravenously into a patient.  
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brachytherapy   Placement of radioactive material (small sealed containers) in contact with or implanted into tumor tissue.  
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cachexia   General ill health (muscle wasting and weight loss) associated with severe, chronic disease, such as cancer.  
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carcinogen   Substance that produces cancer.  
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carcinoma   Cancerous tumor.  
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carcinoma in situ   Localized cancer, confined to its site of origin.  
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cauterization   Process of burning tissue to destroy it.  
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cellular oncogenes   Pieces of DNA that, when broken or dislocated, can cause a normal cell to become malignant.  
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chemotherapy   Treatment with drugs for cancer.  
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combination chemotherapy   Use of several chemotherapeutic agents together for treatment of tumors.  
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cryosurgery   Use of subfreezing temperature to destroy tissue.  
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cystic tumor   A cystic tumor forms large open spaces filled with fluid.  
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dedifferentiation   Loss of differentiation of cells; reversion to a more primitive, embryonic cell type.  
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deoxyribonucleic acid   Genetic material within the nucleus of a cell; controls cell division and protein synthesis.  
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differentiating agents   Drugs that promote tumor cells to differentiate, stop growing and die.  
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differentiation   Specialization of cells; unspecialized cells are modified and altered to form specific and characteristic types and functions.  
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dysplastic   Pertaining to abnormal formation or development of cells; not clearly malignant.  
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electron beams   Low-energy beams of radiation for treatment of skin or surface tumors.  
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en bloc resection   Removal of a tumor with a large area of surrounding tissue containing lymph nodes.  
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encapsulated   Surrounded by a capsule; benign tumors are encapsulated.  
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epidermoid   Resembling epidermis or the outer layer of skin. Epidermoid tumors are composed of thin, plate-like cells.  
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excisional biopsy   Removal of tumor and a margin of normal tissue.  
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exenteration   Wide resection involving removal of the tumor, its organ of origin, and all surrounding tissue in the body space.  
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exfoliative cytology   Cells are scraped from a region of suspected disease and examined under the microscope.  
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external beam radiation   Radiation applied to a tumor from a distant source, such a machine (linear accelerator).  
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fiberoptic colonoscopy   Visual examination of the colon using a fiber optic instrument (endoscope).  
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fibrosarcoma   Malignant tumor of fibrous or connective tissue.  
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fibrosis   Abnormal condition (proliferation) of fibrous connective tissue; occurring in the lung as a side effect of radiation for lung cancer.  
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follicular   Pertaining to forming small, glandular sacs.  
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fractionation   Method of administering radiation treatment in small, repeated doses rather than in a few large doses.  
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fulguration   Destruction of tissue by electric sparks generated by a high-frequency current.  
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fungating tumor   Gross description of tumor growth in which cells pile one on top of another and project from the tissue surface.  
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genetic screening   Family members are tested to determine whether they have inherited a cancer-causing gene.  
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grading of tumors   Evaluating the microscopic appearance of tumor cells to determine their degree of differentiation or maturity and thus malignant transformation.  
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gray   Unit of absorbed radiation dose.  
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gross description of tumors   Visual appearance of tumors, such as cystic, fungating, inflammatory, medullary, necrotic, polypoid, ulcerating, and verrucous.  
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hyperplasia   Increased growth in numbers of normal cells.  
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incisional biopsy   Piece of tumor is removed for examination to establish a diagnosis.  
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infiltrative   Pertaining to extending beyond normal tissue boundaries.  
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invasive   Having the ability to enter and destroy surrounding tissue.  
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irradiation   Exposure to any form of radiant energy such as light, heat or x-rays.  
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laparoscopy   Visual examination of the abdominal cavity using small incisions and a laparoscope (endoscope).  
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linear accelerator   Devise that produces high-energy x-ray (photon) beams for treatment of deep-seated tumors.  
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malignant tumor   Cancerous tumor.  
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mammography   X-ray examination of the breast.  
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medullary tumor   Large, fleshy tumors.  
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mesenchymal   Pertaining to embryonic connective tissue from which all connective tissues arise. Sarcomas are tumors of connective tissues that arise originally from mesenchymal cells.  
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metaplasia   Conversion of normal cells into a less differentiated type in response to chronic stress or injury.  
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metastasis   Spread of a cancerous tumor to another site (change of place) or secondary location (meta-  
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microscopic description of tumors   Appearance of tumors as viewed under the microscope. Examples are alveolar, carcinoma in situ, dysplastic, Epidermoid, and follicular tumors.  
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mitosis   Cell division of replication of cells; creation of two identical daughter cells from a parent cell.  
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mixed tissue tumors   Tumors composed of different types of tissue (epithelial as well as connective tissues).  
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modality   Method of treatment.  
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molecularly targeted drugs   Anticancer drugs designed to block the function of growth factors, their receptors, and signaling pathways in specific tumor cells.  
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morbidity   Damage to normal tissue or the state of being diseased.  
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mucinous   Pertaining to cystic tumors filled with mucus.  
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mucositis   Inflammation of mucous membranes; often a side effect of radiation therapy or chemotherapy.  
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mutagenic   Pertaining to producing a mutation.  
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mutation   Change in genetic material (DNA) of a cell.  
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myelosuppression   Bone marrow depression or formation of blood cells (leukopenia, anemia, and thrombocytopenia).  
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necrotic tumor   Tumor that contains dead cells.  
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needle (core) biopsy   Insertion of a needle into tissue to remove a core of cells to examine under a microscope; needle aspiration.  
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neoplasm   New growth (tumor); benign or malignant tumor.  
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neuroblastoma   Malignant childhood tumor originating in cells of the nervous system.  
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nucleotide   Unit of DNA (gene) composed of a sugar, phosphate, and a base. The sequence of nucleotides composing a gene is the genetic code.  
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oncogene   Region of DNA in tumor cells (cellular oncogene) or in viruses (viral oncogene) that cause cancer.  
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oncology   Study of tumors (malignant tumors).  
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osteosarcoma   Malignant tumor of bone.  
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palliative   Relieving, but not curing symptoms.  
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papillary   Pertaining to nipple-like projections. A papillary tumor forms microscopic nipple-like or finger-like projections of cells.  
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pedunculated   Processing a stem or stalk (peduncle).  
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pharmacokinetics   Study of the distribution and removal of drugs in the body over a period of time.  
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photon therapy   Radiation treatment using x-rays and gamma rays delivered to tumor tissue via a linear accelerator.  
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pleomorphic   Pertaining to a variety of shapes or cell types.  
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pneumonitis   Inflammation of the lungs.  
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polypoid tumor   Resembling a polyp (benign growth) that protrudes from a base.  
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protein marker tests   Measurements of the level of specific protein in the blood or on the surface of tumor cells; PSA, CA-125, and alpha-fetoprotein are examples.  
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protocol   Detailed plan for treatment of an illness.  
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proton therapy   Subatomic particles (protons) produced by a cyclotron deposit absorbed does of radiation at a finite, focused point in the body.  
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radiation   Energy carried by a steam of particles.  
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radiocurable tumor   Tumor cells that are destroyed with radiotherapy.  
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radionuclide scans   Radioactive substances (radionuclides) are injected intravenously and scans (images) are taken of organs.  
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radioresistant tumor   Tumor cells that require large doses of radiation to be destroyed.  
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radiosensitive tumor   Tumor in which radiation can cause death of cells without damage to surrounding tissue.  
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radiosensitizers   Drugs that increase the sensitivity of tumor cells to x-rays.  
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radiotherapy   Treatment of tumors using radiation; radiation oncology.  
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relapse   Return of symptoms of disease.  
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remission   Partial or complete disappearance of symptoms of disease.  
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retinoblastoma   Malignant tumor of the retina of the eye; childhood malignancy.  
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ribonucleic acid   Cellular substance that, along with DNA, plays a role in protein synthesis.  
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sarcoma   Cancerous tumor derived from connective or fleshy tissue.  
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scirrhous   Pertaining to hard, densely packed tumors, overgrown with fibrous tissue.  
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serous   Pertaining to a clear fluid (serum) that remains after blood has clotted. Serous tumors are cystic tumors filled with a thin, water fluid, resembling serum.  
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sessile   Type of polyp that extends from a broad base as opposed to growing on a stalk.  
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simulation   Study prior to radiation therapy using CT scan or MRI to map treatment. It is required for all patients undergoing radiation therapy.  
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solid tumor   Tumor composed of a mass of cells.  
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staging of tumors   System of evaluating the extent of spread of tumors.  
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stem cell transplant   Stem cells (immature blood cells) are harvested from the bloodstream of a patient and then reinfused after the patient has received chemotherapy.  
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stereotactic radiosurgery   A single large dose of radiation delivered under stereotactic (highly precise) guidance to destroy a vascular abnormality or treat small intracranial tumors.  
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steroids   Complex, naturally occurring chemicals, such as hormones, that are used in cancer chemotherapy.  
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teletherapy   Radiation delivered to a tumor from a distant source, such as a linear accelerator or cyclotron.  
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ulcerating tumor   Growth that has open, exposed surfaces resulting from death of overlying tissue.  
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verrucous tumor   Tumor, whose growth pattern, resembles a wart.  
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viral oncogenes   Pieces of DNA from viruses that infect a normal cell and cause it to become malignant.  
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virus   Infectious agent that reproduces by entering a host cell and using the host’s genetic material to make copies of itself.  
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xerostomia   Dryness of the mouth.  
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