Drug Actions Farias
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| heartburn, esophageal stricture, hemorrhage, hoarseness, pneumonia | GERD
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| enlarge esophogaus, dysphagia, regurge, chestpain, wieght loss, mucosal rupture/ulceration, putrid materia, aspiration pneumonia | esophogeal achalasia
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| chronic, gnawing, burning ab/chest pain, GI bleeding, acute massive hemorrage, perforation, infection, obstruction | ulcer disease
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| N/V, Bloating, constipation/diarrhea, bacterial overgrowht, blood glucose, weight loss, bezoars | gastroparesis
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| discomfort after eating to severe pain, jaundice | cholelithiasis
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| inflammation, infection sepsis | cholecystitis
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| dehydratio, malnutrition, weight loss, fatigue | diarrhea
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| Osmotic D. | Malabsorptive nutrients/electrolytes, retain water
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| secretory | increase rate of fluid out of epith. into lumen
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| inglammatory | loss of mucus, blood, protein, cytokeine release
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| host immune response to GI antigens, t and B cells disrupt, ulcerations/inflammation of entire bowl, perforation, fistula, abscess, SI, bleeding, cancer, protein losing enteropathy, disorder skin eye mucus, arthritis, nephrolithiasis, thromboembolic dis, | IBD-Crohns
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| rare-preforation, obstuction, fistula, bleeding, prostein losing enterpathy, higher risk of carcinoma | IBD-ulcerative colitis
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| refined food, muscose and submucosa herniate | diverticular disease
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| diverticulosis | initial stage, chronic constipations, ab. pain, flatulence, sigmoid colon, abnormal colon wall
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| diverticular bleeding | blood in stool, painless, no inflammation
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| diverticulitis | focal area inflammation, ab. pain, fever, risk of sbscess, perfoartion, fistula, intestineal obstruction.
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| decreased solubility, increase precip. of uring substnace, dehydration, high protein diet, HTN, infection | renal stones
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| pain in kidney, distension, anuria, azotemia, hematuria, renal damage, HTN, infection or abscess | renal stones
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| abrupt hematuria, proteinuria, Dec. GFR, water/salt retention | acute glomerulonephritis
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| complete renal failure in weeks | rapidly professive glomerulonephritis
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| acute flomerulonephritis to chronic | chronic glomerulonephritis
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| nephrotic syndrome | proteinuria, albunimura, edema, hyperlipidema
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| acute Glom. | immune mediated attackw ith deposition of immunocomplexes and complement in capillaries
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| rapidly progressive glom. | extracapillary proliferation with gaps in basement membrane
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| chronic glomerul. | sclerosis, subepithelial protein deposits and cell. proliferation
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| nephrotic syndrome | no cellular infiltrate of inflammation, antigen-ab in basement membrane
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| renal stones, heart failure, glomerulonephritis, nevrosis, hypovolemia, septis | acute renal failure
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| fatigue, malaise, peripheral edema, dyspnea, dec. FG, increased BUN, urine not conc., NA retention, azotemia, orthopnea, rales | acture renal failure
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| DM, glomerulonephristis, HTN, infeciton PKD, Obstruction | Chronic renal failure
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| loss of nephron function, uremia, renal hormones change, fluid shifts | chronic renal failure
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| hyperalekemia, anemia, clotting abnormaliites, CV and pul. dysfunction, osteomalacia and osteoporosis, metabolic acidosis, CHF, Edema | Chronic renal failure
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| biliubin, nutrients, drugs, foreign substances | hepatic portal vien (to liver)
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| bilirubine metabolic hormones and drugs, nutrients | hepatic artery (to liver)
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| bile salts, bilirubin, water, ions, phospholipids | bile duct (away liver)
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| glucose, plasma proteins, urea, D3, somatomedins, metabolites | hepatic veing (away liver)
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| glucose, fat, protein synthesis, urea production, detox, storage | liver
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| acute, stool, fecal, oral, sex, abrupt onset, antibiotics against reinfection, vac. kills hepatocytes | hep. A viral
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| Hep. B viral | acute, 6%chronich, blood, sex, insiduious, vaccine
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| hep C viral | acute, 70-80% chronic, blood
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| Hep. D Viral | acute, chronic, HBV coinfection, blood, sex, high mortality, insidious onset
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| hep e viral | acute, stool, oral, most severe acute
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| acute hep | hepatocyte infection, inflammatory response, heptatocyte degeneration/necrosis, kupfer cells, cholestasis with bile plug, hepatic loss 1-5%,
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| acute hep. viral | prodrome icteric, convalescent
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| prodrome | fever, malaise, fatigue, N/V, anoreaxia, ab. pain, HA, cough, skin, myalgia, arthralgia
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| icteric | improve prodome ex. ab. pain, splenomegaly, jaundic, light poo, dark urin, eccchymoses, encephalopathy, renal dysfunction
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| convalescent | normal except liver tests
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| acute: toxic | similar to viral
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| acetominophen | CYP-iNOS activaiton-apoptosis,
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| chronic hepatitis | viral, drugs, genetic (antitrypsin), immune
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| chronic hepatitis | little or no fibrosis, anorexia, fatigue, malaise, RUQ ab. pain, jaundice, hepatomegaly, cirrhosis
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| cirrhosis | fibrosis, protal hypertension, scaring, regenerative nodules
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| cirrhosis | ascites, h. encephalopathy, gastroesophageal varices, feminization, coagulopathy, hepatorenal syndrom, hypoalbuminemia, peripheral edema, bac. peritonitis, splenomegaly, spider angioma
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Created by:
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