Stack #60629
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| amphetamine | inhibits NE release
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| amphetamine | Tx. ADHD
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| metryosine | inhibits NE synthesis
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| metryosine | Tx. pheocromacytoma
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| reserpine | inhibits NE packaging
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| reserpine | Tx. hypertension
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| desipramine | inhibits NE reuptake
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| desipramine | Tx. depression
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| tolcapone | inhibits NE metabolism
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| tolcapone | Tx. Parkinson's
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| isocarboxazid | inhibits NE metabolism
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| isocarboxazid | Tx. depression
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| milrinone | phospodiesterase inhibitor
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| milrinone | Tx. heart failure
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| milrinone | MOA- increase cAMP
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| isoproterenol | B1 and B2 agonist
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| isoproterenol | MOA- increase cAMP (increase HR and contractility)
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| isoproterenol | Tx. heart failure, asthma, emphysema
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| verapamil | Ca channel blocker (phenylalkylamine)
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| verapamil | MOA- decrease Ca influx into smooth muscle=vasodilation
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| verapamil | Tx. hypertension
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| levosimendan | Ca sensitizer
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| levosimendan | MOA- increase sensitivity of cardiac troponin to Ca = vasodilation
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| levosimendan | Tx. heart failure
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| digoxin | Cardiac glycoside
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| digoxin | Tx. heart failure
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| digoxin | MOA- inhibit Na/K ATPase; decrease Ca efflux= increased contractility and force
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| diltiazem | Ca channel blocker (benothiazepine)
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| diltiazem | MOA- decrease Ca influx into sm. muscle= vasodilation
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| diltiazem | Tx. hypertension
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| dopamine | dopamine agonist
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| dopamine | dose dependent b/c precursor for NE (vasoconstriction)
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| dopamine | Tx. heart failure
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| terbutaline | B2 agonist
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| terbutaline | Tx. asthma, emphysema
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| terbutaline | MOA- increase cAMP, P phospholamban, increase SERCA, increase Ca resequestration by SR= faster relaxation
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| dobutamine | B1 agonist
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| dobutamine | Tx. heart failure
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| dobutamine | MOA- increased cAMP and activation of Ca channels
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| hydrochlorothiazide | diuretic (thiazide)
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| hydrochlorothiazide | Tx. hypertension, edema, renal failure, CHF
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| hydrochlorothiazide | increase Na excretion
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| spironolactone | diuretic (K sparing)
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| spironolactone | increase renal excretion of Na
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| spironolactone | Tx. hypertension, CHF, edema, renal failure
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| nifedipine | Ca channel blocker (dihydropyridine)
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| nifedipine | block Ca influx= decrease contraction
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| nifedipine | Tx. hypertension, vasospastic angina, arrhythmias
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| losartan | ARB
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| losartan | blocks angiotensin II receptor
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| losartan | Tx. hypertension, CHF
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| captopril | ACE inhibitor
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| captopril | Tx. hypertension, CHF, MI
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| captopril | inhibits angiotensin converting enzyme
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| captopril | side effect- bradykinin=cough
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| furosemide | diuretic (loop)
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| furosemide | MOA-increase renal excretion of Na= decrease plasma V and VR
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| furosemide | Tx. hypertension, CHF, edema, renal failure
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| nitroglycerine | NO pro-drug (vasodilator)
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| nitroglycerine | MOA- increase NO production=relaxation
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| nitroglycerine | Tx. angina, CHF, MI
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| acetazdamide | diuretic (carbonic anhydrase inhibitor)
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| acetazdamide | Tx. hypertension, CHF, edema, renal failure
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| acetazdamide | MOA- increase renal excretion of Na (can cause Acid-base disorder)
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| atropine | anticholinergic - muscarinic antagonist
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| atropine | decrease airway secretion
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| tolterodine | anticholinergic - muiscarinic antagonist
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| tolterodine | Tx. overactive bladder
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| pilocarpine | cholinomimetics- muscarinic agoinst
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| pilocarpine | Tx. ocular hypertension, open and closed glaucoma
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| demecarium | cholinergics-indirect agonist
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| demecarium | inhibits acetylcholinesterase
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| demecarium | myasthenia gravis, open angle glaucoma
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| ambenonium | cholinergics-indirect agonist
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| ambenonium | inhibits acetylcholinesterase
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| ambenonium | myasthenia gravis, open angle glaucoma
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| pindolol | non cardioselective B antagonist with ISA
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| pindolol | Tx. hypertension
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| metoprolol | B1 antagonist w/o ISA
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| metoprolol | Tx. hypertension
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| penbutolol | non cardioselective B antagonist with ISA
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| penbutolol | Tx. hypertension
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| carteolol | noncardioselective b antagonist with ISA
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| cateolol | Tx. hypertension
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| prazosin | a1 antagonist = vasodilator
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| prazosin | Tx. hypertension
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| labetolol | non cardioselective b blocker w/o ISA
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| labetolol | Tx. hypertension
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| pancuronium | ganglionic blocker- nicotinic antagonist
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| pancuronium | Tx. hypertensive crisis with dissecting aortic aneurisum
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| nadolol | noncardioselective b blocker w/o ISA
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| nadolol | Tx. hypertension
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| clonidine | a2 agonist (sympatholytics =decrease sympathic acitivity at vasomotor center)
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| clonidine | Tx. hypertension
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| propranolol | noncardioselective b blocker w/o ISA
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| propranolol | Tx. hypertension
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| carvedilol | noncardioselective b blocker w/o ISA (a1 antagonist)
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| carvedilol | Tx. hypertension
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| phenylephrine | a1 agonist (vasoconstrictor)
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| phenylephrine | Tx. hypotension, nasal congestion
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| norepinephrine/noradrenaline | a1 agonist = vasoconstrictor
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| NE | Tx. hypotension
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| yohimbine | a2 antagonist
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| yohimbine | Tx. ED
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| acebutolol | cardioselective b blocker with ISA
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| acebutolol | Tx. hypertension
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| mecamylamine | ganglionic blocker
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| mecamylamine | Tx. hypertensive crisis
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| atenolol | cardioselective b blocker w/o ISA
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| atenolol | Tx. hypertension
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| ipratropium bromide | atrovent
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| ipratropium bromide | anticholinergic- muscarinic antagonist
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| ipratropium bromide | MOA- relax airway sm. muscle (se=increase mucus viscosity)
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| theophylline | theo-dur
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| theophylline | phosphodiesterase inhibitor
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| theophylline | MOA- prevent cAMP breakdown= relax sm. muscle
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| montelukast | singulair
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| montelukast | leukotriene antagonist
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| albuterol | proventil, ventolin
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| albuterol | b2 agonist
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| albuterol | MOA- relax airway sm. muscle
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| beclomethasone | beclovent
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| beclomethasone | inhaled corticosteroid
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| beclomethasone | prevent inflammation
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| fluticasone | flovent
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| fluticasone | inhaled corticosteroid
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| fluticasone | prevent inflammation
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| prednisone | systemic corticosteroid
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| prednisone | prevent inflammation
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| zafirlukast | accolate
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| zafirlukast | leukotriene antagonist
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| salmeterol | serevent
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| salmeterol | b2 agonist
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| sameterol | MOA- relax sm. muslce
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| cromolyn sodium | intal
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| cromolyn sodium | mediator inhibitor
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| atropine | MOA- bronchodilator
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| cromolyn sodium | MOA- prevents mast cell degranulation (histamine release)
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mmmiller
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