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block 2 drugs
Stack #60629
| Question | Answer |
|---|---|
| amphetamine | inhibits NE release |
| amphetamine | Tx. ADHD |
| metryosine | inhibits NE synthesis |
| metryosine | Tx. pheocromacytoma |
| reserpine | inhibits NE packaging |
| reserpine | Tx. hypertension |
| desipramine | inhibits NE reuptake |
| desipramine | Tx. depression |
| tolcapone | inhibits NE metabolism |
| tolcapone | Tx. Parkinson's |
| isocarboxazid | inhibits NE metabolism |
| isocarboxazid | Tx. depression |
| milrinone | phospodiesterase inhibitor |
| milrinone | Tx. heart failure |
| milrinone | MOA- increase cAMP |
| isoproterenol | B1 and B2 agonist |
| isoproterenol | MOA- increase cAMP (increase HR and contractility) |
| isoproterenol | Tx. heart failure, asthma, emphysema |
| verapamil | Ca channel blocker (phenylalkylamine) |
| verapamil | MOA- decrease Ca influx into smooth muscle=vasodilation |
| verapamil | Tx. hypertension |
| levosimendan | Ca sensitizer |
| levosimendan | MOA- increase sensitivity of cardiac troponin to Ca = vasodilation |
| levosimendan | Tx. heart failure |
| digoxin | Cardiac glycoside |
| digoxin | Tx. heart failure |
| digoxin | MOA- inhibit Na/K ATPase; decrease Ca efflux= increased contractility and force |
| diltiazem | Ca channel blocker (benothiazepine) |
| diltiazem | MOA- decrease Ca influx into sm. muscle= vasodilation |
| diltiazem | Tx. hypertension |
| dopamine | dopamine agonist |
| dopamine | dose dependent b/c precursor for NE (vasoconstriction) |
| dopamine | Tx. heart failure |
| terbutaline | B2 agonist |
| terbutaline | Tx. asthma, emphysema |
| terbutaline | MOA- increase cAMP, P phospholamban, increase SERCA, increase Ca resequestration by SR= faster relaxation |
| dobutamine | B1 agonist |
| dobutamine | Tx. heart failure |
| dobutamine | MOA- increased cAMP and activation of Ca channels |
| hydrochlorothiazide | diuretic (thiazide) |
| hydrochlorothiazide | Tx. hypertension, edema, renal failure, CHF |
| hydrochlorothiazide | increase Na excretion |
| spironolactone | diuretic (K sparing) |
| spironolactone | increase renal excretion of Na |
| spironolactone | Tx. hypertension, CHF, edema, renal failure |
| nifedipine | Ca channel blocker (dihydropyridine) |
| nifedipine | block Ca influx= decrease contraction |
| nifedipine | Tx. hypertension, vasospastic angina, arrhythmias |
| losartan | ARB |
| losartan | blocks angiotensin II receptor |
| losartan | Tx. hypertension, CHF |
| captopril | ACE inhibitor |
| captopril | Tx. hypertension, CHF, MI |
| captopril | inhibits angiotensin converting enzyme |
| captopril | side effect- bradykinin=cough |
| furosemide | diuretic (loop) |
| furosemide | MOA-increase renal excretion of Na= decrease plasma V and VR |
| furosemide | Tx. hypertension, CHF, edema, renal failure |
| nitroglycerine | NO pro-drug (vasodilator) |
| nitroglycerine | MOA- increase NO production=relaxation |
| nitroglycerine | Tx. angina, CHF, MI |
| acetazdamide | diuretic (carbonic anhydrase inhibitor) |
| acetazdamide | Tx. hypertension, CHF, edema, renal failure |
| acetazdamide | MOA- increase renal excretion of Na (can cause Acid-base disorder) |
| atropine | anticholinergic - muscarinic antagonist |
| atropine | decrease airway secretion |
| tolterodine | anticholinergic - muiscarinic antagonist |
| tolterodine | Tx. overactive bladder |
| pilocarpine | cholinomimetics- muscarinic agoinst |
| pilocarpine | Tx. ocular hypertension, open and closed glaucoma |
| demecarium | cholinergics-indirect agonist |
| demecarium | inhibits acetylcholinesterase |
| demecarium | myasthenia gravis, open angle glaucoma |
| ambenonium | cholinergics-indirect agonist |
| ambenonium | inhibits acetylcholinesterase |
| ambenonium | myasthenia gravis, open angle glaucoma |
| pindolol | non cardioselective B antagonist with ISA |
| pindolol | Tx. hypertension |
| metoprolol | B1 antagonist w/o ISA |
| metoprolol | Tx. hypertension |
| penbutolol | non cardioselective B antagonist with ISA |
| penbutolol | Tx. hypertension |
| carteolol | noncardioselective b antagonist with ISA |
| cateolol | Tx. hypertension |
| prazosin | a1 antagonist = vasodilator |
| prazosin | Tx. hypertension |
| labetolol | non cardioselective b blocker w/o ISA |
| labetolol | Tx. hypertension |
| pancuronium | ganglionic blocker- nicotinic antagonist |
| pancuronium | Tx. hypertensive crisis with dissecting aortic aneurisum |
| nadolol | noncardioselective b blocker w/o ISA |
| nadolol | Tx. hypertension |
| clonidine | a2 agonist (sympatholytics =decrease sympathic acitivity at vasomotor center) |
| clonidine | Tx. hypertension |
| propranolol | noncardioselective b blocker w/o ISA |
| propranolol | Tx. hypertension |
| carvedilol | noncardioselective b blocker w/o ISA (a1 antagonist) |
| carvedilol | Tx. hypertension |
| phenylephrine | a1 agonist (vasoconstrictor) |
| phenylephrine | Tx. hypotension, nasal congestion |
| norepinephrine/noradrenaline | a1 agonist = vasoconstrictor |
| NE | Tx. hypotension |
| yohimbine | a2 antagonist |
| yohimbine | Tx. ED |
| acebutolol | cardioselective b blocker with ISA |
| acebutolol | Tx. hypertension |
| mecamylamine | ganglionic blocker |
| mecamylamine | Tx. hypertensive crisis |
| atenolol | cardioselective b blocker w/o ISA |
| atenolol | Tx. hypertension |
| ipratropium bromide | atrovent |
| ipratropium bromide | anticholinergic- muscarinic antagonist |
| ipratropium bromide | MOA- relax airway sm. muscle (se=increase mucus viscosity) |
| theophylline | theo-dur |
| theophylline | phosphodiesterase inhibitor |
| theophylline | MOA- prevent cAMP breakdown= relax sm. muscle |
| montelukast | singulair |
| montelukast | leukotriene antagonist |
| albuterol | proventil, ventolin |
| albuterol | b2 agonist |
| albuterol | MOA- relax airway sm. muscle |
| beclomethasone | beclovent |
| beclomethasone | inhaled corticosteroid |
| beclomethasone | prevent inflammation |
| fluticasone | flovent |
| fluticasone | inhaled corticosteroid |
| fluticasone | prevent inflammation |
| prednisone | systemic corticosteroid |
| prednisone | prevent inflammation |
| zafirlukast | accolate |
| zafirlukast | leukotriene antagonist |
| salmeterol | serevent |
| salmeterol | b2 agonist |
| sameterol | MOA- relax sm. muslce |
| cromolyn sodium | intal |
| cromolyn sodium | mediator inhibitor |
| atropine | MOA- bronchodilator |
| cromolyn sodium | MOA- prevents mast cell degranulation (histamine release) |
Created by:
mmmiller
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