Heart, veins
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show | Depol authorythmic cells, spreads to non-autorythmic & opens
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what is involved in Circulation? | show 🗑
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what is Mid-to-late diastole? | show 🗑
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show | Change in heart wall; dialated cardiomyopathy- stretches out, bldy sitting around
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show | -35(arteriole end)-15(venous end)
-capillaries will burst and push nutrients out
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Factors that affect resistance? | show 🗑
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show | -calcium
-digitalis
-epinephrine
-glucagon
-thyroxine
Increase contractility, increase of force of heart
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ABC of heart health | show 🗑
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show | From arterial to venous
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Other heart rate modifiers | show 🗑
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show | Cornea & lens
Ligaments & tendons
Epithelium
Cartilage
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Types of bld vessels | show 🗑
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show | Kidnerys
retina
spleen
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show | Mm contaction in heart by Ca2+
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show | -Porous, small intestine, kidney, endocrine organs, some endothelial have fenestration
-More permeable to fluid and solutes
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Tunica Media | show 🗑
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show | Most common
Don't stretch/ tissues die off
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Mitochondria create? | show 🗑
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Arrythmias | show 🗑
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Arteries do what? | show 🗑
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show | -Tunica Intima
-Pericytes- help support wall
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show | Tunica intima only
length-60,000
width-10 micrometers
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Heart failure classification | show 🗑
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Veins characteristics | show 🗑
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show | Inflamation of the heart; viruses cause L ventricle to fail
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Factors that affect EDV and ESV | show 🗑
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show | Exchange vessels
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Vascular anastomosis parts developed best for it? | show 🗑
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show | slow and intermittent
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show | largest arteries in heart, closer to the heart, do not vasodialate or vasoconstrict
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Capillaries job and position? | show 🗑
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Sinusoidal | show 🗑
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Types of veins | show 🗑
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show | Futher away from heart
Deliver bld to specific body organs- kidney gonads
Thickest tunica media
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show | Continious
Fenestrated
Sinusoidal
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Ventricular systole | show 🗑
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FAulty heart valves | show 🗑
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show | Heart beats on its own, ANS can modify HR and force of contraction
-Sympathetic-Neurotransmitter Norapanephrin
-Parasympathetic-Neurotransmitter acetacholamine
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Cardiac mm contraction- autorythmic cells | show 🗑
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Venous adaptation for overcoming gravity | show 🗑
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Intercalated disks | show 🗑
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show | systole- time contraction of ventricles
diastole- time relaxation of ventricles
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show | Tunica intima, media and externa
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Circulation formula | show 🗑
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layers of the tunica intima? | show 🗑
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show | SV=EDV-ESV
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Veins do what? | show 🗑
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Heart rate modifier:age | show 🗑
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show | Afterload problem, increase force on L ventricle, diastole heart failure
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Varicose veins: What happens when valves malfunction? | show 🗑
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Tunica Externa | show 🗑
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Common causes of heart failure- | show 🗑
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show | Autorythmic spontaneously generate signal
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Heart failure signs and symptoms | show 🗑
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show | Changes in HR
-chemical, age, gender, exercise, body temp
-tachycardia and bradycardia
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show | Muscular, elastic, arterioles
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Arterioles feed into what? | show 🗑
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show | Hormones-Thyroxine, epinephrine
Ions-Calcium, Potassium
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show | CO=HRxSV, amt of bld pumped through L vent in 1 min
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Congenital heart defects common in? how does it affect heart? | show 🗑
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show | Regulate BP by altering R to BF
-Norepinephrine and epinephrine- released in response to stress and nicotine, both cause vasoconstriction
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show | ANP-produced by heart
Relaxed by atrial myocytes in response to:
atrial dystension, sympathetic stimulation of heart, increase Na+ lvls, angiotension 2, endothelium
Cause bld volume to decrease
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show | Produced by hypothalamus when bp is low
cause kidneys to conserve H2O
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show | Intercalated disks signal every mm to contract
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show | Does not pulsate, lumen get large as pressure decreases
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show | Kidneys receive inadequate flow, they release renin
Renin acts as an enzyme to make angiotensin 2
Angiotensin 2 causes increase in BP; release aldosterone & ADH
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show | Lipid soluble substances diffuse through lipid bilayer
H2O soluble pass through fluid-filled intercellular clefts
fenestrations
large molecules are actively transported by pinocytotic vesicles or cabeolae
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Myogenic controls of autoregulation | show 🗑
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show | At base of true capillares
So blood can move from arteries to veins, into capellaries
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show | Amt to which heart mm is stretched before contraction
-Venous Return- bld returning to heart increase force of contraction
increase VR=increase EDV=increase CO
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Capillary Beds | show 🗑
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show | Intercalated disks
Mitochondria
Calcium delivery
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Direct renal mechanism; independent or dependent of hormones? | show 🗑
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Afterload | show 🗑
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Continious | show 🗑
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What factors affect contractility? | show 🗑
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Differences in mechanism of contraction : cardiac | show 🗑
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- inotropid factor | show 🗑
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show | Multiple capalaries drop O2 bld here
-smallest veins
-endothelium with a few pericytes & maybe some smooth mm cells
-porous
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show | Renin- angiotension mechanism
when arterial bld pressure decrease kidneys, release renin which produces angiotensin 2
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Pathology of BP regulation: Hypotension: causes- | show 🗑
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Hypertenstion; 3 categories of hypertension? | show 🗑
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Maintaining BP- 3 mechanisms of maintaing BP | show 🗑
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show | Neural controls; maintain BP by altering resistance to BF
-Baroreceptrors-stretch receptors
-Chemoreceptors-detect chemicals in bld
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show | Respond to stretch in arteries caused by increased BP. cause vasodialation/restriction when stretched.
Located in walls of:
Carotid sinuses
--CArotid sinus reflex
aortic arch
most large arteries in neck & thorax
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Chemoreceptors respond to decrease in? increase in? when activated, causes? | show 🗑
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Early Diastole | show 🗑
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show | primary-unidentifiable cause, but involve
diet
obesity
age diabetes mellitus
heredity
stress
smoking
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show | Indentifiable, underlying conditions
10% have it, atherosclerosis, hyperthyroid
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Tissue perfusion is necessary for? | show 🗑
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show | Automatic adjustment of BF to each tissue in proportion to needs.
Done by: metabolically- increase tissue perfussion
Myogencially- autoregulation in smooth mm
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Myo | show 🗑
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show | origin
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Metabolic controls of autoregulation | show 🗑
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Created by:
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