Homework Packet #9
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| The antibody class which is in highest concentration in serum is ______________. | Igg
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| Cell-mediated immunity is brought about primarily by ______________ lymphocytes. | T
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| _______________ is the antibody class that is associated with hypersensitivity or allergic responses. | IgE
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| A foreign substance that induces an immune response by causing antibody production is an _______________. | Antigen (Ag)
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| An _______________ is the common name for a hypersensitive condition. | Allergy
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| An individual who is able to produce a normal immune response is said to be _______________ while one who has reduced or absent ability to produce an immune response is said to be _______________. | Immunocompetent/Immunocompromised
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| The _______________ is the portion of an antigen that reacts specifically with an antibody. | Epitope
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| An assay that uses an enzyme-labeled antibody as a reactant is an _____________________. | Enzyme Immunoassay (EIA)
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| _______________ mediated immunity of provided primarily by cytokines and lymphocytes. | Cell
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| The operation of blood banks is ultimately regulated by the ______________. | FDA
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| The process of removing a specific blood component and returning the remaining blood to the circulation is ________________. | Apheresis
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| A _______________ is a living tissue or organ placed into the body from another source or site. | Transplant
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| The term used for the study of human blood groups is _______________. | Immunohematology
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| _______________ is a parasitic disease that has been shown to be able to be transmitted through transfusion. | Malaria
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| The department in the clinical laboratory in which blood is typed and tested for transfusion is the _________________. | Blood Bank
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| An antiserum is a serum that contains _________________. | Antibodies
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| The _______________ is a special centrifuge that is used in blood typing procedures. | Serifuge
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| The _______________ system was discovered by Karl Landsteiner in 1900. | ABO
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| Any of several forms of a gene responsible for hereditary variation is called an ________________. | Allele or Allelic Gene
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| The use of known cells to identify unknown antibodies in a patient's serum is called ________________. | Reverse grouping
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| Donor blood is routinely tested for ABO type and Rh _______________ antigen. | D
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| Rh D negative patients should be transfused with _______________ blood. | RhD Negative
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| The Rh D antigen is identified using _______________ techniques. | Agglutination
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| The two main methods of becoming immunized to the Rh D antigen are through pregnancy and _______________. | Transfusion
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| _______________ is the condition in which a fetus or newborn is affected by maternal antibodies directed against the infants RBCs. | HDN - Hemolytic Disease of the Newborn
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| The cell type that is infected by the Epstein-Barr virus in infectious mononucleosis is the _______________. | B Lymphocytes
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| The rapid test for infectious mononucleosis is designed to detect the presence of _______________ antibodies which are of the ________________ class. | Heterophile/IgM
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| The blood cell that is seen under the microscope in infectious mononucleosis is called an ________________. | Atypical
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| The time between exposure to an infectious agent and the appearance of symptoms is the ________________. | Incubation period
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| _______________ is an autoimmune disease characterized by pain, inflammation, and deformity of the joints. | RA - Rheumatoid Arthritis
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| Synovial is a term that relates to the lubricating fluid of the ________________. | Joints
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| An antibody directed against one's own tissue is called an ________________. | Auto-antibody
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| In the RF slide test, latex particles are coated with _______________. | Immunoglobulin (Human Igg)
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| AGGLUTINATION | The clumping or aggregation of particulate antigens due to reaction with a specific antibody.
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| ALLERGY | A condition resulting from an exaggerated immune response.
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| ANAMNESTIC RESPONSE | A rapid increase in blood immunoglobulins following a second exposure to an antigen.
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| (AB) ANTIBODY | A serum protein that is induced by, and reacts specifically with, a foreign substance.
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| (AG) ANTIGEN | A foreign substance that induces an immune response by causing the production of antibodies.
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| AUTOIMMUNE DISEASE | A disease caused when the immune response is directed at one's own tissues.
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| (B-CELL) B LYPMHOCYTE | The type of lymphocyte primarily responsible for the humoral immune response.
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| CELL-MEDIATED IMMUNITY | Immunity provided by T-Lymphocytes and cytokines.
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| COMPLEMENT | A group of plasma proteins that can be activated in immune reaction, can cause cell lysis, and can help initiate the inflammatory response.
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| CYTOKINE or (LYMPHOKINE) | Any of various non-antibody proteins secreted by cells of the immune system and that help regulate the immune response.
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| EIA - ENZYME IMMUNOASSAY | An assay that uses an enzyme-labeled antibody as a reactant.
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| EPITOPE | The portion of an antigen that reacts specifically with an antibody.
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| HUMORAL IMMUNITY | Immunity provided by B lymphocytes and antibodies.
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| Ig - IMMUNOGLOBULINS | Serum proteins that are induced by and react specifically with antigens.
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| IMMUNOLOGY | The branch of medicine encompassing the study of the immune processes and immunity.
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| IMMUNOSUPPRESSION | Suppression of the immune response by physical, chemical, or biological means.
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| MACROPHAGES or (TISSUE MONOCYTE) | Long-lived phagocytic tissue cells derived from blood monocytes that functions in the destruction of antigens and serve as antigen-presenting cells.
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| MONOCLONAL ANTIBODY | Antibody derived from a single cell line or clone.
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| PLASMA CELL | A differentiated B lymphocyte that produces antibodies.
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| POLYCLONAL ANTIBODIES | Antibodies derived from more than one cell line.
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| PRECIPITATION | Formation of an insoluble antigen-antibody.
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| RIA - RADIO IMMUNOASSAY | An assay using a test component labeled with a radioisotope.
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| SEROCONVERSION | The appearance of antibody in the serum of an individual following exposure to an antigen.
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| T-CELL - T Lymphocyte | The type pf lymphocyte responsible for the cell-mediated immune response.
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| TITER | The reciprocal of the highest dilution that gives the desired reaction; the concentration of a substance determined by titration.
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| AABB | International association that sets blood bank standards, accredits blood bands, and promotes high standards of performance.
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| APHERESIS | The process of removing a specific component, such as plasma or platelets, from donor blood, and returning the blood to donor circulation.
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| ALLELE | One of two (or more) alternate forms of a gene responsible for hereditary variation.
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| BLOOD GROUP ANTIBODY | A serum protein (immunoglobulin) that reacts specifically with a blood group antigen.
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| BLOOD GROUP ANTIGEN | A substance or structure on the red blood cell membrane that stimulates antibody formation and reacts with that antibody.
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| HISTOCOMPATABILITY TESTING | Performance of assays to determine if donor and recipient tissue are compatible.
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| REVERSE GROUPING | The use of known cells to identify unknown antibodies in the patient's serum or plasma.
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| GENOTYPE | The allelic genes that are responsible for a trait.
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| PHENOTYPE | In blood banking, the blood type determined by blood typing sera.
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| RhD IMMUNE GLOBIN (RhIg) | A concentrated, purified solution of human anti-D antibody used for injection.
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| CHRONIC FATIGUE SYNDROME (CFS) | A syndrome characterized by prolonged fatigue and other non-specific symptoms and for which the cause remains unknown.
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| INCUBATION PERIOD | The time elapsed between exposure to an infectious agent and the appearance of syptoms.
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| LATENT | Dormant, or in an inactive or hidden phase.
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| AUTOANTIBODY | An antibody directed against the self.
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| SYNOVIAL | Of, or pertaining to, the lubricating fluid of the joints.
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| FORWARD GROUPING | The use of known antisera to identify unknown antigens on a patient's cells.
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| _______________ is a positive reaction in the RF slide test. | Agglutination
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