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Clin Lab Proced.09

Homework Packet #9

QuestionAnswer
The antibody class which is in highest concentration in serum is ______________. Igg
Cell-mediated immunity is brought about primarily by ______________ lymphocytes. T
_______________ is the antibody class that is associated with hypersensitivity or allergic responses. IgE
A foreign substance that induces an immune response by causing antibody production is an _______________. Antigen (Ag)
An _______________ is the common name for a hypersensitive condition. Allergy
An individual who is able to produce a normal immune response is said to be _______________ while one who has reduced or absent ability to produce an immune response is said to be _______________. Immunocompetent/Immunocompromised
The _______________ is the portion of an antigen that reacts specifically with an antibody. Epitope
An assay that uses an enzyme-labeled antibody as a reactant is an _____________________. Enzyme Immunoassay (EIA)
_______________ mediated immunity of provided primarily by cytokines and lymphocytes. Cell
The operation of blood banks is ultimately regulated by the ______________. FDA
The process of removing a specific blood component and returning the remaining blood to the circulation is ________________. Apheresis
A _______________ is a living tissue or organ placed into the body from another source or site. Transplant
The term used for the study of human blood groups is _______________. Immunohematology
_______________ is a parasitic disease that has been shown to be able to be transmitted through transfusion. Malaria
The department in the clinical laboratory in which blood is typed and tested for transfusion is the _________________. Blood Bank
An antiserum is a serum that contains _________________. Antibodies
The _______________ is a special centrifuge that is used in blood typing procedures. Serifuge
The _______________ system was discovered by Karl Landsteiner in 1900. ABO
Any of several forms of a gene responsible for hereditary variation is called an ________________. Allele or Allelic Gene
The use of known cells to identify unknown antibodies in a patient's serum is called ________________. Reverse grouping
Donor blood is routinely tested for ABO type and Rh _______________ antigen. D
Rh D negative patients should be transfused with _______________ blood. RhD Negative
The Rh D antigen is identified using _______________ techniques. Agglutination
The two main methods of becoming immunized to the Rh D antigen are through pregnancy and _______________. Transfusion
_______________ is the condition in which a fetus or newborn is affected by maternal antibodies directed against the infants RBCs. HDN - Hemolytic Disease of the Newborn
The cell type that is infected by the Epstein-Barr virus in infectious mononucleosis is the _______________. B Lymphocytes
The rapid test for infectious mononucleosis is designed to detect the presence of _______________ antibodies which are of the ________________ class. Heterophile/IgM
The blood cell that is seen under the microscope in infectious mononucleosis is called an ________________. Atypical
The time between exposure to an infectious agent and the appearance of symptoms is the ________________. Incubation period
_______________ is an autoimmune disease characterized by pain, inflammation, and deformity of the joints. RA - Rheumatoid Arthritis
Synovial is a term that relates to the lubricating fluid of the ________________. Joints
An antibody directed against one's own tissue is called an ________________. Auto-antibody
In the RF slide test, latex particles are coated with _______________. Immunoglobulin (Human Igg)
AGGLUTINATION The clumping or aggregation of particulate antigens due to reaction with a specific antibody.
ALLERGY A condition resulting from an exaggerated immune response.
ANAMNESTIC RESPONSE A rapid increase in blood immunoglobulins following a second exposure to an antigen.
(AB) ANTIBODY A serum protein that is induced by, and reacts specifically with, a foreign substance.
(AG) ANTIGEN A foreign substance that induces an immune response by causing the production of antibodies.
AUTOIMMUNE DISEASE A disease caused when the immune response is directed at one's own tissues.
(B-CELL) B LYPMHOCYTE The type of lymphocyte primarily responsible for the humoral immune response.
CELL-MEDIATED IMMUNITY Immunity provided by T-Lymphocytes and cytokines.
COMPLEMENT A group of plasma proteins that can be activated in immune reaction, can cause cell lysis, and can help initiate the inflammatory response.
CYTOKINE or (LYMPHOKINE) Any of various non-antibody proteins secreted by cells of the immune system and that help regulate the immune response.
EIA - ENZYME IMMUNOASSAY An assay that uses an enzyme-labeled antibody as a reactant.
EPITOPE The portion of an antigen that reacts specifically with an antibody.
HUMORAL IMMUNITY Immunity provided by B lymphocytes and antibodies.
Ig - IMMUNOGLOBULINS Serum proteins that are induced by and react specifically with antigens.
IMMUNOLOGY The branch of medicine encompassing the study of the immune processes and immunity.
IMMUNOSUPPRESSION Suppression of the immune response by physical, chemical, or biological means.
MACROPHAGES or (TISSUE MONOCYTE) Long-lived phagocytic tissue cells derived from blood monocytes that functions in the destruction of antigens and serve as antigen-presenting cells.
MONOCLONAL ANTIBODY Antibody derived from a single cell line or clone.
PLASMA CELL A differentiated B lymphocyte that produces antibodies.
POLYCLONAL ANTIBODIES Antibodies derived from more than one cell line.
PRECIPITATION Formation of an insoluble antigen-antibody.
RIA - RADIO IMMUNOASSAY An assay using a test component labeled with a radioisotope.
SEROCONVERSION The appearance of antibody in the serum of an individual following exposure to an antigen.
T-CELL - T Lymphocyte The type pf lymphocyte responsible for the cell-mediated immune response.
TITER The reciprocal of the highest dilution that gives the desired reaction; the concentration of a substance determined by titration.
AABB International association that sets blood bank standards, accredits blood bands, and promotes high standards of performance.
APHERESIS The process of removing a specific component, such as plasma or platelets, from donor blood, and returning the blood to donor circulation.
ALLELE One of two (or more) alternate forms of a gene responsible for hereditary variation.
BLOOD GROUP ANTIBODY A serum protein (immunoglobulin) that reacts specifically with a blood group antigen.
BLOOD GROUP ANTIGEN A substance or structure on the red blood cell membrane that stimulates antibody formation and reacts with that antibody.
HISTOCOMPATABILITY TESTING Performance of assays to determine if donor and recipient tissue are compatible.
REVERSE GROUPING The use of known cells to identify unknown antibodies in the patient's serum or plasma.
GENOTYPE The allelic genes that are responsible for a trait.
PHENOTYPE In blood banking, the blood type determined by blood typing sera.
RhD IMMUNE GLOBIN (RhIg) A concentrated, purified solution of human anti-D antibody used for injection.
CHRONIC FATIGUE SYNDROME (CFS) A syndrome characterized by prolonged fatigue and other non-specific symptoms and for which the cause remains unknown.
INCUBATION PERIOD The time elapsed between exposure to an infectious agent and the appearance of syptoms.
LATENT Dormant, or in an inactive or hidden phase.
AUTOANTIBODY An antibody directed against the self.
SYNOVIAL Of, or pertaining to, the lubricating fluid of the joints.
FORWARD GROUPING The use of known antisera to identify unknown antigens on a patient's cells.
_______________ is a positive reaction in the RF slide test. Agglutination
Created by: luparl
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