Homework Packet #8
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| _______________ is the mineral involved in the hemostasis pathway. | Ionized Calcium
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| The vitamin K dependent coagulation factors are manufactured in the _______________. | Liver
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| _______________ is a serious intravascular clotting condition that can occur after certain bacterial infections. | DIC - Disseminated Intravascular Coagulation
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| Platelets undergo a shape change when they come into contact with exposed tissue _______________. | Collagen
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| Thrombus is another name for a _______________. | Blood clot (Clot)
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| _______________ is the process that occurs when platelets stick to a damaged vessel. | Adhesion
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| The action of blood vessels constricting to slow the flow of blood is called ________________. | Vasoconstriction
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| When platelets adhere to the vessel wall, they are activated and begin to _______________. | Aggregate
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| The hemophilias are inherited as __________ genes on the __________ chromosome. | Sex-linked/X
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| Hemophilia B is also called _________________. | Christmas Disease
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| Hemophilia B is caused by a functional deficiency of _______________. | Coagulation Factor IX
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| A test for quantitative and qualitative abnormalities of platelets is the _______________. | Bleeding time
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| In the Ivy bleeding time test, the blood pressure cuff is inflated to a pressure of _______________. | 40 mmhg
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| In the bleeding time test, the two functions measured are small vessel function and ________________ function. | Platelet
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| The ________________ is the puncture site for the Ivy bleeding time test. | Forearm
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| The prothrombin time is used to follow _______________ therapy. | Coumadin or (Oral anticoagulants)
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| _______________ is the anticoagulant used to collect blood for a prothrombin time test. | Sodium Citrate
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| The reagent used in the prothrombin test is _______________. | Thromboplastin
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| What are the three ways in which prothrombin time can be reported? | 1. In seconds 2. PR - Prothrombin Ration or 3. INR - International Normalized Ratio
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| A patient's Coumadin is usually adjusted to keep the prothrombin time at _______________ times normal. | 1.3 - 1.5
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| Coumadin is an anticoagulant derived from ____________________. | Coumarin or (Warfarin)
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| The activated partial thromboplastin time is used to monitor patients who are on _______________ therapy. | Heparin
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| The APTT is used to screen for abnormalities in the _______________ pathway and the common pathway. | Intrinsic
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| Partial thromboplastin is the ________________ portion of tissue thromboplastin. | Lipid
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| The calcium necessary for clot formation in the APTT is supplied by the chemical compound ________________. | CaCl2 (Calcium Chloride)
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| _______________ is the anticoagulant used to collect the sample for the APTT test. | Sodium Citrate
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| Specimens for the Dade D-dimer test must be collected in the anticoagulant _________________. | Sodium Citrate
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| In the latex tests, any D-dimer present in the patient sample reacts with a highly specific monoclonal _______________. | Antibody
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| A serious condition in which widespread thromboses and secondary hemorrhage occurs is called ________________. | DIC - Disseminated Intravascular Coagulation
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| The ACT is the _______________. | Activated Clotting Time
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| The HMT is a new version of the _______________. | ACT
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| The HMT is especially valuable for monitoring patients who are receiving moderate to high doses of ________________. | Heparin
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| ADHESION | The act of two parts or surfaces sticking together.
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| AGGREGATION | The collecting of separate objects into one mass.
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| COAGULATION FACTORS | A group of plasma proteins (and mineral calcium) involved in blood clotting.
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| COLLAGEN | A protein connective tissue found in skin, bone, ligaments, and cartilage.
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| FIBRIN DEGRADATION PRODUCTS | Degradation products formed when plasmin cleaves fibrin or fibrinogen.
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| FIBRINOLYSIS | Enzymatic breakdown of a blood clot.
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| HEMOSTASIS | The process of stopping bleeding, which includes clot formation and dissolution.
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| VASOCONSTRICTION | The narrowing of the diameter of a blood vessel.
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| HEMOPHILIA | A bleeding disorder resulting from a hereditary coagulation factor deficiency or dysfunction.
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| PETECHIAE | Small, purplish hemorrhagic spots on the skin.
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| DYSFUNCTION | Impaired or abnormal function.
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| COUMADIN | An anticoagulant derived from coumarin that is administered orally to prevent slow clotting.
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| INR - International Normalized Ratio | A way of reporting a prothrombin time that takes into consideration the sensitivity of the thromboplastin used and the mean of the normal prothrombin time in the facility's population.
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| PROTHROMBIN TIME | A coagulation screening test used to monitor oral anticoagulant therapy.
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| VITAMIN K | A vitamin essential for production of coagulation factors II, VII, IX, and X.
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| ANGIOPLASTY | Surgical repair of a vessel.
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| D-dimer | One of the products formed from the breakdown of fibrin by plasmin.
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| XDP - CROSS-LINKED FIBRIN DEGRADATION PRODUCTS | Fibrin-degradation products that contain the D-dimer cross-linked region.
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Created by:
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