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Clin Lab Proced.08
Homework Packet #8
| Question | Answer |
|---|---|
| _______________ is the mineral involved in the hemostasis pathway. | Ionized Calcium |
| The vitamin K dependent coagulation factors are manufactured in the _______________. | Liver |
| _______________ is a serious intravascular clotting condition that can occur after certain bacterial infections. | DIC - Disseminated Intravascular Coagulation |
| Platelets undergo a shape change when they come into contact with exposed tissue _______________. | Collagen |
| Thrombus is another name for a _______________. | Blood clot (Clot) |
| _______________ is the process that occurs when platelets stick to a damaged vessel. | Adhesion |
| The action of blood vessels constricting to slow the flow of blood is called ________________. | Vasoconstriction |
| When platelets adhere to the vessel wall, they are activated and begin to _______________. | Aggregate |
| The hemophilias are inherited as __________ genes on the __________ chromosome. | Sex-linked/X |
| Hemophilia B is also called _________________. | Christmas Disease |
| Hemophilia B is caused by a functional deficiency of _______________. | Coagulation Factor IX |
| A test for quantitative and qualitative abnormalities of platelets is the _______________. | Bleeding time |
| In the Ivy bleeding time test, the blood pressure cuff is inflated to a pressure of _______________. | 40 mmhg |
| In the bleeding time test, the two functions measured are small vessel function and ________________ function. | Platelet |
| The ________________ is the puncture site for the Ivy bleeding time test. | Forearm |
| The prothrombin time is used to follow _______________ therapy. | Coumadin or (Oral anticoagulants) |
| _______________ is the anticoagulant used to collect blood for a prothrombin time test. | Sodium Citrate |
| The reagent used in the prothrombin test is _______________. | Thromboplastin |
| What are the three ways in which prothrombin time can be reported? | 1. In seconds 2. PR - Prothrombin Ration or 3. INR - International Normalized Ratio |
| A patient's Coumadin is usually adjusted to keep the prothrombin time at _______________ times normal. | 1.3 - 1.5 |
| Coumadin is an anticoagulant derived from ____________________. | Coumarin or (Warfarin) |
| The activated partial thromboplastin time is used to monitor patients who are on _______________ therapy. | Heparin |
| The APTT is used to screen for abnormalities in the _______________ pathway and the common pathway. | Intrinsic |
| Partial thromboplastin is the ________________ portion of tissue thromboplastin. | Lipid |
| The calcium necessary for clot formation in the APTT is supplied by the chemical compound ________________. | CaCl2 (Calcium Chloride) |
| _______________ is the anticoagulant used to collect the sample for the APTT test. | Sodium Citrate |
| Specimens for the Dade D-dimer test must be collected in the anticoagulant _________________. | Sodium Citrate |
| In the latex tests, any D-dimer present in the patient sample reacts with a highly specific monoclonal _______________. | Antibody |
| A serious condition in which widespread thromboses and secondary hemorrhage occurs is called ________________. | DIC - Disseminated Intravascular Coagulation |
| The ACT is the _______________. | Activated Clotting Time |
| The HMT is a new version of the _______________. | ACT |
| The HMT is especially valuable for monitoring patients who are receiving moderate to high doses of ________________. | Heparin |
| ADHESION | The act of two parts or surfaces sticking together. |
| AGGREGATION | The collecting of separate objects into one mass. |
| COAGULATION FACTORS | A group of plasma proteins (and mineral calcium) involved in blood clotting. |
| COLLAGEN | A protein connective tissue found in skin, bone, ligaments, and cartilage. |
| FIBRIN DEGRADATION PRODUCTS | Degradation products formed when plasmin cleaves fibrin or fibrinogen. |
| FIBRINOLYSIS | Enzymatic breakdown of a blood clot. |
| HEMOSTASIS | The process of stopping bleeding, which includes clot formation and dissolution. |
| VASOCONSTRICTION | The narrowing of the diameter of a blood vessel. |
| HEMOPHILIA | A bleeding disorder resulting from a hereditary coagulation factor deficiency or dysfunction. |
| PETECHIAE | Small, purplish hemorrhagic spots on the skin. |
| DYSFUNCTION | Impaired or abnormal function. |
| COUMADIN | An anticoagulant derived from coumarin that is administered orally to prevent slow clotting. |
| INR - International Normalized Ratio | A way of reporting a prothrombin time that takes into consideration the sensitivity of the thromboplastin used and the mean of the normal prothrombin time in the facility's population. |
| PROTHROMBIN TIME | A coagulation screening test used to monitor oral anticoagulant therapy. |
| VITAMIN K | A vitamin essential for production of coagulation factors II, VII, IX, and X. |
| ANGIOPLASTY | Surgical repair of a vessel. |
| D-dimer | One of the products formed from the breakdown of fibrin by plasmin. |
| XDP - CROSS-LINKED FIBRIN DEGRADATION PRODUCTS | Fibrin-degradation products that contain the D-dimer cross-linked region. |
Created by:
luparl
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