Neuro
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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CAGE | cutdown/control
annoyed
guilt about use
eye opener (drink first thing in the morning)
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Acute symptoms of Niacin deficiency | Wernicke's--anterograde amnesia,
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Chronic symptoms of Niacin deficiency | Korsakoff's ---irreversible damages. these people have hole in hippocampus so they have persistent memory problems
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What do you do with alcoholics if they present at the ER | Do not give them IV glucose because they will further deplete their niacin/NADH and will aggravate their condition. Give them intramuscular thiamine
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Delerium Tremors | distinguished from dementia because this condition mental status waxes and wanes. The patient may hallucinate
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Idiosyncratic alcohol intoxication | some people become agitated a and uninhibited with
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Treating alcohol withdrawals | Barbituates (cross-reactive at GABA-R). Alcohol (tapering) can also be used
Librium, Adavam, valium
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alcohol abuse prevention and sobriety | disulfaram (antabuse), naltrexone, AA
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Disulfaram | works on the acetyl-aldehyde dehydrogenase--> will cause nausea and vomiting when you drink because acetyl-aldehyde accumulates
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If you see a young athlete with psychotic symptoms what will be high on your differential? | anabolic steroid abuse
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Amphetamine Uses | Narcolepsy, ADD, Obesity
(eg related drugs meridian, provigil)
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Commonality between all drugs of abuse (or chemicals, foods) | They all stimulate nucleus accumbens (may reinforce the behavior). The neurotransmitters at the end of this circuit are dopamine and opiates
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Welbutrin (buproprion) | one of few antidepressants that is not an SSRI; works by increasing NE/DA. It is used to treat people trying to quit smoking cigarettes
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