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final patho

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Term
Definition
Genomics   Study of stricture, function, and analysis of human genome  
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Epigenetics   External modification of DNA  
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Epigenomics   Chemical compounds that instruct where and when genes are expressed  
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Genome   all humans 99.9% identical  
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Genomics   study of entire genome vs disease and disorder mechanism  
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Benign tumor   non-cancerous, slow growth, well defined, don't spread (non-invasive)  
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Neoplasm   abnormal growth  
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Apoptosis   destruction of cells  
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Oncogenes   cancer causing genes  
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Hyperplasia   increased cell number  
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Atrophy   shrinking in cell size  
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Metaplasia   cell changes form; less likely to lead to cancer  
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Hypertrophy   increase in cell size  
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Dysplasia   abnormal development of cells; more likely to lead to cancer  
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Proto-oncogenes   normal cell genes responsible for normal growth and division  
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Tumor suppressor genes   suppress tumors  
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DNA repair genes   repairs DNA and errors during replication  
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Caretaker genes   repairs damaged DNA  
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Telomeres   protective caps on ends of chromosome (cancer removes these)  
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Neovascualrization   growth of new vessels  
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Tumor-associated macrohpages   key cell that promotes tumor survival  
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Tumor markers   substance expressed by tumors or normal tissue in response to tumor  
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Paraneoplastic syndrome   caused when a tumor marker expresses itself  
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Cachexia   shivering  
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Carcinoma in situ   has not spread  
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Ischemia   Lack of profusion  
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Infarction   Tissue death  
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autosomal   Everything other than X and Y  
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Hemophilia   blood disorder (clotting effect)  
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