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Genetics/genome
final patho
| Term | Definition |
|---|---|
| Genomics | Study of stricture, function, and analysis of human genome |
| Epigenetics | External modification of DNA |
| Epigenomics | Chemical compounds that instruct where and when genes are expressed |
| Genome | all humans 99.9% identical |
| Genomics | study of entire genome vs disease and disorder mechanism |
| Benign tumor | non-cancerous, slow growth, well defined, don't spread (non-invasive) |
| Neoplasm | abnormal growth |
| Apoptosis | destruction of cells |
| Oncogenes | cancer causing genes |
| Hyperplasia | increased cell number |
| Atrophy | shrinking in cell size |
| Metaplasia | cell changes form; less likely to lead to cancer |
| Hypertrophy | increase in cell size |
| Dysplasia | abnormal development of cells; more likely to lead to cancer |
| Proto-oncogenes | normal cell genes responsible for normal growth and division |
| Tumor suppressor genes | suppress tumors |
| DNA repair genes | repairs DNA and errors during replication |
| Caretaker genes | repairs damaged DNA |
| Telomeres | protective caps on ends of chromosome (cancer removes these) |
| Neovascualrization | growth of new vessels |
| Tumor-associated macrohpages | key cell that promotes tumor survival |
| Tumor markers | substance expressed by tumors or normal tissue in response to tumor |
| Paraneoplastic syndrome | caused when a tumor marker expresses itself |
| Cachexia | shivering |
| Carcinoma in situ | has not spread |
| Ischemia | Lack of profusion |
| Infarction | Tissue death |
| autosomal | Everything other than X and Y |
| Hemophilia | blood disorder (clotting effect) |