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Generic
Brand
Selected Adverse Effects
PHARMACY CATEGORY
Consideration
Buprenorphine   Buprenex   1. Respiratory depression 2. Dizziness 3. Sedation   Analgesic, Opioid   show
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show Sublimaze   1. Constipation 2. Confusiondizziness 3. Respiratory depression   Analgesic, Opioid   ISMP High-alert medication  
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show Dilaudid   1. Constipation 2. Flushing 3. Hypotension 4. Itching 5. Respiratory depression   Analgesic, Opioid   ISMP High-alert medication  
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Ketorolac   Toradol   1. Dyspepsia 2. GI symptoms (nausea, abdominal pain, constipation, diarrhea) 3. GI bleeding (rare but serious)   show  
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Morphine   Duramorph, Infumorph   1. Constipation 2. Drowsiness 3. Nausea/ vomiting 4. Respiratory depression   show ISMP High-alert medication Use only preservative-free solutions for epidural administration  
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Ketamine   show 1. Prolonged emergence from anesthesia (confusion, delirium, dreamlike state, hallucinations, vivid imagery)   Antidepressant; General Anesthetic   ISMP High-alert medication  
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Lidocaine   Xylocaine   1. Dizziness 2. Nausea vomiting 3. Paresthesia 4. Hypotension   Antiarrhythmic Agent, Class Ib; Local Anesthetic   show
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Propofol   Diprivan   show General Anesthetic   ISMP High-alert medication Expires 12 hours from opening. All tubing and unused portions should be discarded at that time.  
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show Cerebyx   1. Ataxia 2. Nystagmus 3. Somnolence   Antiseizure Agent, Hydantoin   Rate infusion:not faster than 150 mg PE/ minute  
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Levetiracetam   Keppra   show Antiseizure Agent, Miscellaneous    
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Phenytoin   Dilantin   1. Exfoliate dermatitis 2. Stevens-Johnson syndrome 3. Blood dyscrasias 4. CNS toxicity   Antiseizure Agent, Hydantoin   show
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show Depacon   1. Thrombocytopenia 2. Tremor 3. Diplopia   Antimanic Agent; Antiseizure Agent, Miscellaneous; Histone Deacetylase Inhibitor    
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Haloperidol lactate   Haldol   1. Extrapyramidal reactions 2. Hyperkinesia 3. Akathisia   First Generation (Typical) Antipsychotic   show
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Olanzapine   Zyprexa   1. Drowsiness 2. Extrapyramidal symptoms   show  
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Ziprasidone   show 1. Drowsiness 2. Extrapyramidal symptoms   Antimanic Agent; Second Generation (Atypical) Antipsychotic    
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Diazepam   Valium   1. Drowsiness 2. Slow breathing rate   Benzodiazepine   show
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show Ativan   1. Drowsiness 2. Slow breathing rate   Benzodiazepine   ISMP High-alert medication  
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Midazolam   Versed   1. Drowsiness 2. Slow breathing rate 3. Decreased tidal volume   show ISMP High-alert medication Some formulations contain benzyl alcohol; use a preservative-free injection formulation in neonates  
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Acetylcysteine   Acetadote   1. Anaphylaxis   Antidote; Mucolytic Agent   show
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Atropine   Atropine   1. Anticholinergic side effects (dry mucous membranes, urinary retention) 2. Tachycardia   show  
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Flumazenil   Romazicon   1. Vomiting 2. Tremor 3. Ataxia   show May precipitate seizures in patients who have been on long-term benzodiazepine therapy  
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Leucovorin     1. GI side effects (nausea/vomiting/diarrhea) 2. Fatigue   Antidote   show
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Naloxone   show 1. Dizziness 2. Flushing 3. Injection site reactions 4. Nausea/vomiting   Antidote; Opioid Antagonist   Because naloxone has a short half-life, it may need to be administered multiple times until opioid wears off  
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Octreotide   Sandostatin   show Antidiarrheal; Antidote; Somatostatin Analog    
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Zoledronic acid   Reclast; Zometa   1. Bone pain 2. Arthralgia 3. Hypotension   show Administer through a separate IV line. Do not mix with any calcium or divalent cation containing solutions.  
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Dexamethasone   show 1. Fluid retention 2. Fragile skin 3. Hyperglycemia 4. Hypertension 5. Mood changes   Anti-inflammatory Agent; Antiemetic; Corticosteroid,    
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Hydrocortisone   show 1. Fluid retention 2. Fragile skin 3. Hyperglycemia 4. Hypertension 5. Mood changes   Corticosteroid    
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Methylprednisolone sodium succinate   show 1. Fluid retention 2. Fragile skin 3. Hyperglycemia 4. Hypertension 5. Mood changes   Corticosteroid    
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show Benadryl   1. Sedation 2. Anticholinergic effects (e.g., urinary retention, dry mouth)   Histamine H1 Antagonist, First Generation   Diphenhydramine injection can cause local skin necrosis and should never be given subcutaneous or intradermal. For IM injections, make sure they are given deep IM.  
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Promethazine   Phenergan   show Histamine H1 Antagonist, First Generation   ISMP High-alert medication Vesicant, can cause severe tissue damage/necrosis. Should not be administered IM or IV push. Should be diluted and administered slowly as an IV intermittent infusion or via a central line to avoid extravasation.  
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Ranitidine   show 1. Constipation 2.Diarrhea 3. Nausea   Histamine H2 Antagonist    
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Ondansetron   Zofran   1. Constipation 2. Diarrhea 3. Headache   show  
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show Protonix   1. Constipation 2. Diarrhea 3. Headache   PPI    
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Infliximab   Remicade   show Immunosuppressant Agent, TNF-alpha   ISMP High-alert medication Short-stability medication - use within 3 h and use in-line ≤1.2 micron low protein binding filter. not infuse or mix with other solutions . May require premedications prior to infusion to decrease infusion-related reactions.  
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show Rituxan   1. Infusion-related reactions (e.g., chills, fever, rigors, myalgias, headache, cough) 2. Fatigue   Immunosuppressant Agent; Monoclonal Antibody   ISMP High-alert medication Patients should be premedicated prior to infusion and infusions should be titrated upwards to decrease infusion-related reactions.  
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Oxytocin   Pitocin   1. Headache 2. Nausea, vomiting   Oxytocic Agent   show
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