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Skin, Hair, Nails

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Question
Answer
Skin is both:   An organ and a system  
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Epidermis   Derived from surface ectoderm, migrate from neural tube in circumferential bands.  
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Basal Layer   Replaces the surface cells as they slough off  
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Dermis   Derived from mesoderm  
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Melanoblasts/melanocysts   Pigment of neural crest origin, located in basal layer.  
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Sebaceoius glands   secretes the sebum  
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Sweat glands   secretes the sweat  
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Mammary glands   Used to be sweat glands  
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Eumelanin   Brown tinted  
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Pheomelanin   Red color in red color in red hair, Freckles  
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Landmarks of skin   Pigmentation, Thickness, Mobility, Elasticity, Strength, Creases, Dermatoglyphs,and Blaschko's lines  
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Minor Pigmented Nevi anomalies of the Skin   Mongolian spot, Cafe-au-lait spot, Freckles, Lentigines, Hamartomatous, epidermal nevi, angiofibromas  
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Hamartomatous   Benign mix type of cells. Not in the right spot but close.  
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Minor Vascular Nevi anomalies of the Skin   Nevus Flammeus, Port wine stain, Telangiectases, Raised.  
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Deformations of the Skin   Redundant neck skin, Redundant abdominal skin, Abnormal skin creases.  
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Dysplasias of the Skin   Cutis Laxa, Hyperelasticity, Ichthyosis, Epidermolysis bullosum, Hypopigmentation, Hyperpigmentation, Premature thelarche, Absence of the sweat glands.  
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Malformations of the Skin   Cutis Aplasia, Focal Dermal hypoplasia, Skin Tumors - Neurofibromas, Plexiform neurofibromas, Lipomas, Xanthomas, Nevi, Shagreen Pathes, Hypopigmentation - ash-leaf spots, Piebaldism, Vitiligo, Hyperpigmentation, Poikiloderma.  
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Incontinentia pigmenti: What is it and the 4 stages.   X-Linked Dominant, Lethal in males, Any female is a mosaic. 1.) Born with blisters, 2.) Develop raised lines, 3.) Settles to streaky lines, 4.) Linear hypopigmenetation.  
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Hypomelanosis of Ito   Multigenic, Even male to female ratio  
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Poikiloderma   Mixture of Hypo, Hyper and Normal skin color.  
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Peutz-Jehger syndrome   Brown/black macules  
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Hair Embryology   Begins = Week 14 Direction of hair shaft = 15-19 weeks Lanug0 = 20 weeks to birth  
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Landmarks of the Hair   Distribution, Whorls, Color, Eyebrows, Pubic/axillary hair  
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Minor anomalies of the Hair   Low anterior hairline, Widow's peak, Supernumerary whorls.  
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Synophrys   Cornelia De Lange  
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Embryology of the Nails   Fingers separate and nails begin = Week 10 Nails to fingertip = 32-33 weeks Toenails lage behind.  
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Landmarks of the Nails   Shape, Lunula, Cuticle, Curvature, Nail angle  
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Nail abnormalities   Thickened nails, Dystrophic nails  
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Malformations of the Nail   Narrow, Hyperconvex, Tapered, Broad, Small, Aplastic.  
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Created by: btkosewski
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