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RBC and Hemoglobin Worksheet

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Question
Answer
What is the function of the RBC?   Contains Hemoglobin which transports oxygen to the tissues  
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What 5 physiologic factors affect the RBC count?   1 - Age; 2 - Gender; 3 - Altitude; 4 - Body fluid; 5 - Pregnancy  
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How does age affect your RBC count?   2 years to teen count gradually increases  
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How does gender affect your RBC count?   Males have a higher count  
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How does altitude affect your RBC count?   Less oxygen in the air raises RBC  
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How does body fluid affect your RBC count?   1 - Dehydration causes RBC to raise (less fluid to dilute) 2 - Pregnancy – RBC goes down (Fluid retention)  
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Define erythrocytosis -   RBC count above normal  
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What are the three main causes of erythrocytosis?   1 - Polycythemia vera (cancer of the tissue that produces cells) 2 - Burn pt due to dehydration 3 - COPD because of a lack of oxygen  
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Define oligocythemia -   RBC count below normal  
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What are the two main causes of oligocythemia?   1 - Anemia; 2 - Leukemia (Blood has too many WBC so production of RBC is affected)  
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What are normal values for the adult male RBC count?   4.5 - 6.0 million / mm3  
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What are the normal values for the adult female RBC count?   4.0 - 5.5 million / mm3  
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What the different ways to express 52,000,000?   A.) - 5.2 million cells/mm3; B.) - 5.2 million cells / cu.mm.; C.) - 5.2 million cells / uL; D.) - 5.2 x 10 to the 6th cells / uL; E.) 5.2 x 10 to the 12th cells / L  
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What is the function of hemoglobin?   ! - Carry oxygen from the lungs to the tissues by way of diffusion; 2 - Carries 25% of the carbon dioxide from the tissues to the lungs  
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What are the abbreviation for hemoglobin?   Hgb, Hb, hg  
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What is electroresis?   A test that separates genetic types of hemoglobin; - All are hereditary; - All differ in the structure of the polypeptide chains; (Tells how many types & how much of each A1, A2 or F the person has)  
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What are the normal adult male hemoglobin values?   15 - 17 g/dL  
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What are the normal adult female hemoglobin values?   12 - 16 g/dL  
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Which diseases cause a decrease in Hgb?   1 - Anemia; 2 - Leukemia  
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Which diseases cause an increase in Hgb?   1 - Polycythemia vera; 2 - Burn patients; 3 - COPD  
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What is the composition of hemoglobin?   Heme 4% + globin 96%  
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What makes heme?   Starts with iron (Fe+2) and Protoporphyrin; - 4% of molecule  
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What makes globin?   Amino acids and RNA (Ribonucleic acid); 96% of molecule;  
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What is RNA (Ribonucleic acid)?   Instruction or genetic material for assembling the molecule. (RNA tells which Amino Acid assembly and in what order)  
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Where is hemoglobin formed?   In developing bone marrow in about 1 week  
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What is the structure of hemoglobin?   1 - 4 Molecoles of heme (each has iron in Fe+2 [ferrous state]); 2 - 4 Polypeptide chains composed of 2 indentical pairs  
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What are the three normal genetic types of hemoglobin?   1 - A1 which is two alpha & 2 Beta; 2 - A2 which is two alpha & two Delta; 3 - F which is two alpha & two Gamma  
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F or gamma & alpha are found where?   In babies under 6 months; then change to A1's  
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What persent of audults are A1 or A2?   95%  
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Describe the two normal physiologic types of hemoglobin?   1 - Oxyhemoglobin (Scarlet red arterial, oxygenated blood); 2 - Reduced hemoglobin (Blue/red hemoglobin not combined with oxygen)  
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What can abnormal hemoglobin pigmets no longer do?   Cannot carry oxygen  
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Name three abnormal hemoglobin pigments -   1 - Carboxy hemoglobin; 2 - Methemoglobin; 3 - Sulfhemoglobin  
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What color is the abnormal hemoglobin pigment carboxyhemoglobin?   cherry red  
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What color is the abnormal hemoglobin pigment methemoglobin?   Chocolate brown  
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What color is the abnormal hemoglobin pigment sulfhemoglobin?   Lavender  
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How does CLIA classify the STAT-Site M Hgb meter?   Waved  
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How does the STAT-Site M meter determine the Hgb result?   1 - Blood & Reagents; 2 - Hemolyzes; 3 - Hb reacts to form brown; 4 - Amount of color produced is proportional to the concentration of Hb in the sample  
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Which units are used to report a Hgb result?   g/dL  
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What is the normal range for RBC's?   4.5 - 6 million for males & 4.0 - 5.5 million for females  
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What is the normal range for Hbg?   12 - 16 g/dL for women & 15 - 17 g/dL for males  
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What is the normal range for WBC?   4,000 - 11,000 cell/mm3  
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