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RBC and Hemoglobin Worksheet

What is the function of the RBC? Contains Hemoglobin which transports oxygen to the tissues
What 5 physiologic factors affect the RBC count? 1 - Age; 2 - Gender; 3 - Altitude; 4 - Body fluid; 5 - Pregnancy
How does age affect your RBC count? 2 years to teen count gradually increases
How does gender affect your RBC count? Males have a higher count
How does altitude affect your RBC count? Less oxygen in the air raises RBC
How does body fluid affect your RBC count? 1 - Dehydration causes RBC to raise (less fluid to dilute) 2 - Pregnancy – RBC goes down (Fluid retention)
Define erythrocytosis - RBC count above normal
What are the three main causes of erythrocytosis? 1 - Polycythemia vera (cancer of the tissue that produces cells) 2 - Burn pt due to dehydration 3 - COPD because of a lack of oxygen
Define oligocythemia - RBC count below normal
What are the two main causes of oligocythemia? 1 - Anemia; 2 - Leukemia (Blood has too many WBC so production of RBC is affected)
What are normal values for the adult male RBC count? 4.5 - 6.0 million / mm3
What are the normal values for the adult female RBC count? 4.0 - 5.5 million / mm3
What the different ways to express 52,000,000? A.) - 5.2 million cells/mm3; B.) - 5.2 million cells / cu.mm.; C.) - 5.2 million cells / uL; D.) - 5.2 x 10 to the 6th cells / uL; E.) 5.2 x 10 to the 12th cells / L
What is the function of hemoglobin? ! - Carry oxygen from the lungs to the tissues by way of diffusion; 2 - Carries 25% of the carbon dioxide from the tissues to the lungs
What are the abbreviation for hemoglobin? Hgb, Hb, hg
What is electroresis? A test that separates genetic types of hemoglobin; - All are hereditary; - All differ in the structure of the polypeptide chains; (Tells how many types & how much of each A1, A2 or F the person has)
What are the normal adult male hemoglobin values? 15 - 17 g/dL
What are the normal adult female hemoglobin values? 12 - 16 g/dL
Which diseases cause a decrease in Hgb? 1 - Anemia; 2 - Leukemia
Which diseases cause an increase in Hgb? 1 - Polycythemia vera; 2 - Burn patients; 3 - COPD
What is the composition of hemoglobin? Heme 4% + globin 96%
What makes heme? Starts with iron (Fe+2) and Protoporphyrin; - 4% of molecule
What makes globin? Amino acids and RNA (Ribonucleic acid); 96% of molecule;
What is RNA (Ribonucleic acid)? Instruction or genetic material for assembling the molecule. (RNA tells which Amino Acid assembly and in what order)
Where is hemoglobin formed? In developing bone marrow in about 1 week
What is the structure of hemoglobin? 1 - 4 Molecoles of heme (each has iron in Fe+2 [ferrous state]); 2 - 4 Polypeptide chains composed of 2 indentical pairs
What are the three normal genetic types of hemoglobin? 1 - A1 which is two alpha & 2 Beta; 2 - A2 which is two alpha & two Delta; 3 - F which is two alpha & two Gamma
F or gamma & alpha are found where? In babies under 6 months; then change to A1's
What persent of audults are A1 or A2? 95%
Describe the two normal physiologic types of hemoglobin? 1 - Oxyhemoglobin (Scarlet red arterial, oxygenated blood); 2 - Reduced hemoglobin (Blue/red hemoglobin not combined with oxygen)
What can abnormal hemoglobin pigmets no longer do? Cannot carry oxygen
Name three abnormal hemoglobin pigments - 1 - Carboxy hemoglobin; 2 - Methemoglobin; 3 - Sulfhemoglobin
What color is the abnormal hemoglobin pigment carboxyhemoglobin? cherry red
What color is the abnormal hemoglobin pigment methemoglobin? Chocolate brown
What color is the abnormal hemoglobin pigment sulfhemoglobin? Lavender
How does CLIA classify the STAT-Site M Hgb meter? Waved
How does the STAT-Site M meter determine the Hgb result? 1 - Blood & Reagents; 2 - Hemolyzes; 3 - Hb reacts to form brown; 4 - Amount of color produced is proportional to the concentration of Hb in the sample
Which units are used to report a Hgb result? g/dL
What is the normal range for RBC's? 4.5 - 6 million for males & 4.0 - 5.5 million for females
What is the normal range for Hbg? 12 - 16 g/dL for women & 15 - 17 g/dL for males
What is the normal range for WBC? 4,000 - 11,000 cell/mm3
Created by: vinnydog