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Ab. Norm. Cond., Path., Labs & Clinical Procedures

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Question
Answer
acromegaly   chronic metabolic disorder involving gradual enlargement of bones-face, jaw, & extremities  
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Addison disease   hypofunctioning of adrenal cortex; deficiency of all three adrenal steroids  
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adenectomy   removal of gland  
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adrenal virilism   excessive secretion of adrenal androgens  
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adrenalectomy   excision of one or both adrenal glands  
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adrenopathy   disease of adrenal glands  
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cretinism   congenital condition associated with severe hypothyroidism  
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Cushing syndrome   complex of caused by hypersecretion of cortisol from adrenal cortex  
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diabetes insipidus   hyposecretion of ADH; kidney fails to reabsorb needed salts and water  
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diabetes mellitus   lack of insulin secretion or improper utilization of insulin by cells leading to chronic disorder of carbohydrate, fat & protein metabolism in cells  
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dwarfism   congenital hyposecretion of growth hormone from anterior pituitary gland  
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endemic goiter   enlargement of thyroid gland due to lack of iodine in diet  
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endrocrinologist   medical specialist in diagnosis & treatment of endocrine gland disorders  
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exophthalmometry   measures the forward displacement of the eyes  
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exophthalmos   protrusion of eyeball, or proptosis  
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symptom of hypothyroidism   exophthalmos  
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fasting blood sugar   measure that assesses blood glucose levels after an 8- to 10-hour period of fasting  
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test for diabetes mellitus   fasting blood sugar  
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gastroparesis   loss of motility of stomach muscles  
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long-term secondary complication of diabete mellitus   gatroparesis  
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giantism   hypersecretion of growth hormaone from anterior pituitary before puberty  
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glucose tolerance test   measures glucose levels in blood sample taken at various intervals from patient who previously ingested glucose  
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glycosuria   sugar in urine  
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goiter   enlargement of thyroid gland  
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Graves disease   hyperfunctioning of thyroid gland  
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can cause thryotoxicosis   Graves disease  
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Graves disease is   the most common form of hyperthyroidism  
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hirutism   excessive hair growth  
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hypercalcemia   high levels of calcium in bloodstream  
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often due to hyperparathyroidism   hypercalcemia  
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hypercalciuria   high levels of calcium in urine  
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hyperglycemia   high levels of sugar in blood  
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hyperinsulinism   hypersecretion of insulin by the pancreas, resulting in hypoglycemia  
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hyperparathyroidism   hypersecretion of parathormone from parathyroid gland  
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hyperthyroidism   secretion by thryoid gland of greater than normal amount of thyroxine  
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thyroid hormone   thryroxine / T4  
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hypocalcemia   low levels of calcium in blood  
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hyperglycemia   low levels of calcium in blood  
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hypogonadism   deficient functioning of gonads  
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hypoinsulinism   deficient production of insulin  
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hypokalemia   low levels of potassium in blood  
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hyponatremia   low levels of sodium in blood  
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hypoparathyroidism   hyposecretion of parathormone from parathyroid gland leading to hypocalcemia  
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hypophysectomy   removal of pituitary gland  
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hypopituitarism   deficient secretion of hormones from pituitary gland  
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hypothyroidism   decreased secretion of thyroid hormones from thyroid gland  
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ketoacidosis   high levels of ketones in blood  
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myxedema   hypofunctioning of thyroid gland in adults causing accumulation of mucus-like substance under skin  
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nodular goiter   enlargement of thryoid gland due to growth of adenomas on thyroid gland  
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adenomas   nodules on a gland  
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pancreatectomy   excision of pancreas  
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panhypopituitarism   generalized deficiency of all pituitary hormones  
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parathyroidectomy   removal of parathyroid glands  
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pheochromocytoma   benign vascular tumor cusing hypersecretion of epinephrine & norepinephrine  
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polydypsia   excessive thirst  
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radioactive iodine uptake   involves administering iodine and assessing the amount absorbed by the gland  
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indicator of thyroid gland function   radioactive iodine uptake  
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sympathomimetic   pertaining to mimicking/copying effect of sympathetic nervous system  
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norepinephrine & adrenaline are   sympathomimetic hormones  
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syndrome of inappropriate ADH   excessive secretion of antidiuretic hormone from the posterior lobe of pituitary  
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tetany   constant muscle contractions  
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associated with hypocalcemia & hypoparathyroidism   tetany  
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thyroid carcinoma   malignant tumor of thyroid gland  
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thyroid function test   measure the levels of thyroid hormones in the blood  
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thyroid scan   administration of radioactive compound & visualization of thyroid gland with scanning device  
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thyroiditis   inflammation of thyroid gland  
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thyrotoxicosis   hyperthyroidism, overactivity of thyroid gland  
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A1c   blood test that measures glycosylated hemoglobin (HbA1c) to assess glucose control  
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measures ability to respond to a glucose load; test for diabetes   glucose tolerance test  
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HbA1c glycolsylated hemoglobin test   test for presence of glucose attached to hemoglobin  
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high level indicated poor glucose control in diabetes patients   glycolsylated hemoglobin test HbA1c  
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Type 1 diabetes   insulin-dependent diabetes-mellitus  
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multiple endocrine neoplasia   hereditary hormonal disorder marked by adenomas & carcinomas  
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Type 2 diabetes   non-insulin-dependent diabetes-mellitus  
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treatment for Graves disease   radioactive oidine  
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radioimmunoassay   a laboratory measure that assesses hormone levels in plasma  
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mucosal lining of the gastrointestinal tract has cells that produce   hormones gastrin, secretin, and cholecystokinin  
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hormones gastrin, secretin, and cholecystokinin all   help to regulate digestion  
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Specific cells in the wall of the heart   secrete a hormone that causes the kidneys to excrete sodium  
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prostaglandins   hormone-like substance produced body's tissues  
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stimulate contraction of smooth muscle, influence inflammatory response & involved in gastrointestinal & vascular function, including lowering blood pressure   prostoglandins  
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hypersecretion   excessive production of hormones  
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hyposecretion   underproduction of hormones  
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condition characterized by excessive size & stature   giantism  
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if hypersecretion of GH occurs during adulthood this may result   acromegaly  
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condition is acromegaly, not giantism, if hyper sercretion occurs   after the epiphyseal discs of the long bones have been sealed  
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caused by adenomas of the pituitary   gigantism and acromegaly  
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diagnosis of gigantism and acromegaly involve   CT scan & MRI to evaluate the tumor  
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treatment for gigantism and acromegaly ivolves   irradiation or excision of neoplasm  
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hyposecretion of growth hormone produces   pituitary dwarfism  
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pituitary dwarfism   body is properly proportioned, but growth stunted  
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height does not typically exceed 4 feet in   a patient with pituitary dwarfism  
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pituitary dwarfism is usually diagnosed in early childhood with   radioimmunoassay  
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Administering growth hormone to the patient   treats pituitary dwarfism  
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radiographic examination of bones is done with   a radioimmunoassay  
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prepubertal panhypopituitarism   rare disorder associated with infections, autoimmune disorders, tumors, vascular diseases, & destruction of pituitary  
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characterized by dwarfism with normal body proportions, subnormal sexual development, & diminished thyroid/adrenal gland functioning   prepubertal panhypopituitarism  
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postpubertal panhypopituitarism   may result from thrombosis of the pituitary circulation  
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signs/symptoms of postpubertal panhypopituitarism   weakness, fatigue, & intolerance of cold; progression to premature wrinkling of skin & atrophy of thyroid/adrenal glands  
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leads to abnormal retention of water, due to excessive secretion of ADH   syndrome of inapproriate ADH  
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signs of SIADH include   weight gain, vomiting, nausea, muscle weakness, & irritability  
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may develop secondary to tumors, infectious diseases, pathologic reactions to drugs, or trauma   SIADH  
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treatment of SIADH, as secondary, commonly involves   water intake restrictions, along with diagnosis of underlying disease  
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excessive thirst & large quanities of urine excreted due to this condition   diabetes insipidus  
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causes of diabetes insipidus can include   brian tumors, CNS infections/disease, & closed head trauma  
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depending on etiology, treatment of diabetes insipidus can include   fluid replacement & ADH injection/inhalation  
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excision of gland, decreased hormones affecting gland, atrophy of gland & endemic goiter   causes of hypothyroidism  
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characteristics include dwarfism & mental retardation   cretinism  
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treatment for cretinism with thyroid hormone may promote normal physical growth   but may not be able to reverse intellectual deficits  
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most severe form of hypothyroidism   myxedema  
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Persons with myxedema experience   swelling of hands, face & feet  
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due to deficiency of thyroid hormone allowing increase of lipid/fat in bloodstream   patients suffereing from myxedema may also develop atherosclerosis  
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Myxedema can be successfully treated with   administration of thyroid hormone  
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untreated myxedema can lead to   coma & death  
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goiter, may occur in conjunction with   increased, decreased, or normal levels of hormone function  
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Endemic goiter occurs in certain geographic areas among populations of people who   lack sufficient dietary iodine  
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enlargement results from collection of colloid, a jelly-like substance, within gland   goiter  
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may occur in the presence of hyperthyroidism   nodular goiter  
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nodular goiter is also called   adenomatous goiter  
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Graves disease is believed to involve   dysfunction of immune system & influenced by genetics & environment  
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most prominent features of Graves disease    
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exophthalmos is caused by   increased deposits of fat in tissues at back of eye socket  
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absorption of iodine is increased in   hypothyroidism  
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uptake is visualized in an image produced by a thyroid scan   radioactive iodine uptake  
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measures the forward displacement of the eyes in patients with Graves disease   exophthalmometry  
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treatment for Graves disease may involve   partial/total removal of thyroid or drugs to suppress thyroid hyperactivity  
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Radioactive iodine uptake & thyroid scan can help to diagnose   thyrocarcinoma  
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cancerous thyroid neoplasms are called   thyrocarinomas  
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cancerous thyroid neoplasms   are rare  
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grow more slowly than other malignancies   cancerous thyroid neoplasms  
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hard painless nodule in an enlarged thyroid   characterizes cancerous thyroid neoplasms  
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in a thyroid scan nodules that absorb radioactive iodine   show up as "hot"  
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"hot" nodules in a thyroid scan   are usually benign  
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don't take up radioactive iodine, during thyroid scan, showing up as "cold"   are normally tumors & likely to be malignant  
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surgical removal & high-doce radioactive iodine therapy destroying any remaining cells   treatment for tumors of thyroid  
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results in high levels of circulating PTN leading to hypercalcemia   hyperparathyroidism  
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osteitis fibrosa cystica   hypersecretion of PTH causing hypercalcemia leads to fragile bones  
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condition subject to development of cysts   osteitis fibrosa cystica  
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osteitis fibrosa cystica & kideny stones are secondary conditions   of hyperparathyroidism  
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hyperparathyroidism is usually caused by   adenoma of one of parathyroid glands  
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adenoma of one of parathyroid glands is treated by   excision of the tumor  
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muscles & nerves weaken, leading to constant tetany   hypoparathyroidism  
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tetany, related to hypoparathyroidism, is due to   calcium remaining in bone & is unable to enter blood, to reach muscles & nerves  
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adrenal virilism   excess secretions of androgens by inner layer of adrenal cortex  
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females express secondary sex characteristics, including hiruitism & deepening of voice   adrenal virilism  
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adrenal virilism is usually caused by   tumor of adrenal gland  
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adrenal virilism is managed by suppressing hormone overproduction   with medication or surgical excision of adrenal gland  
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Cushing syndrome may reflect the effect of   excessive levels of ACTH on adrenal gland, or tumor of adrenal cortex  
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treatment of arthritis/lupus with glucocorticoids may also cause   Cushing syndrome  
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display obesity, round/moon-like face, fatty deposits on chest, abdomen, & upper back   patients with Cushing syndrome  
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Cushing syndrome can also cause   muscular atrophy, osteoporosis, and hypertension  
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treatment of Cushing syndrome involves   reduction of amout of cortisol secretion pharmacologically/surgically  
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deficiency of mineralcorticoids, glucocorticoids & androgens are seen in   Addison disease  
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Addison disease is believed to be a   dysfunction of immune system; antibodies produced destroying own adrenal tissue  
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Addison disease symptoms include   weakness, fatigue, bronzed pigmentation of skin & mucous membranes  
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bronzed pigmentation of skin/mucous membranes, occuring in Addison disease, caused by   increased levels of MSH & anorexia  
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treatment of Addison disease includes   adrenal hormone replacement & management of underlying cause of illness  
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in pheochromocytoma, chromaffin cells are effected and with chromium salts the   cells stain dark/dusky color  
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signs of pheochromocytoma include   severe headache, palpitations, sweating, nervousness, nausea, vomiting, & persistent/intermittent hypertension  
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surgical excision of the benign vasculat tumor is the usual treatment for   pheochromocytoma  
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symptoms of insulin shock & hypoglycemia include   shakiness, sweating, headache, weakness, and loss of consciousness  
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can result from excessive exercise, too little food or overdose of insulin   insulin shock or severe hypoglycemia  
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insulin shock   hypoglycemic reaction to overdosage of insulin  
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hyperinsulinism may be caused by   insulin-secreting tumor in islets of Langerhans/by exceeding prescribed dose of the hormone  
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administering glucose reverses the condition   hyperinsulinism  
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A deficient supply of insulin in the blood allows for   accumulation of potentially life-threatening amounts of glucose  
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glucose is not properly transported to cells nor is it properly converted within cells as a source of energy when   there are abnormally low levels of insulin  
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High levels of glucose in the bloodstream will   draw water out of cells, causing frequent urination as in diabetes mellitus  
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patients with diabetes mellitus may have increased appetite & food intake due to   glucose being unavailable, cells will seek alternate sources of energy  
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diagnosis of diabetes is confirmed with   fasting blood sugar test & glycoslyated hemoglobin test  
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capable of measuring glucose control over several months   glycosylated hemoglobin test  
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oral glucose tolerance test if used to diagnose   gestational diabetes  
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ketoacids   a carboxylic acid that also contains a carbonyl (CO) group  
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ketoacids are produced because cells are forced   to burn protein & fat instead of glucose  
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buildup of ketoacids   alters the body's metabolic balance  
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diabetic ketoacidosis is a result of   inadequate control of diabetes  
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signs of ketoacidosis include   abdominal pain, nausea, vomitting, & fruity odor of the breath  
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coma and death will result if this is left untreated   ketoacidosis  
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accumulation of fatty materials in the blood vessels, from hyperglycemia, can cause   atherosclerosis, heart attack, and stroke to impaired blood supply to the extremities  
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diabetic nephropathy   kidney disease as result of hyperglycemia  
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diabetic neuropathy   destruction of nerves in the extremities  
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if left untreated hyperglycemia can also cause   diabetic neuropathy & diabetic nephropathy  
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diabetic retinopathy   retinal blood vessel manifestations, including tiny aneurysms and exudation  
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diabetic retinopathy can lead to   vision loss & blindness  
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diabetics are more likely to develop   cataracts & glaucoma  
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plays an important role in both types of diabetes   heriditary  
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in Type1 diabetes little or no insulin is produced because   beta cells of islets of Langerhans have been decreased in number by abnormal autoimmune process  
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usually has its onset during childhood   Type 1 diabetes  
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More than 70% of individuals in whom Type 2 diabetes develops are   obese  
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insulin production is variable; its levels may be decreased, normal, or elevated   Type 2 diabetes  
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Type2 diabetes results from tissue unresponsiveness/resistance to insulin, caused by   hormone receptor defects or too few receptors on surface of target cell membranes  
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gestational diabetes   sometimes develops during pregnancy because of overall hormonal changes at that time  
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gestational diabetes typically resolves after childbirth but may   recur years later as Type 2 diabetes  
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thyroiditis   inflammation of thyroid  
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dystocia   pertaining to pathologic/difficult childbirth  
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endocrinopathy   any disease of endocrine system  
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polyuria   condition of excessive urine  
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