Basics
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each of the black spaces below before clicking
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Help!
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| how many ducts are in the breast | 6-10
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| what is a duct composed of | acini and stroma
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| what is the terminal ductal lobular unit | lobule and duct
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| from the promial to distal ducts | terminal => Lactiferous duct => Lactiferous sinus => collecting duct and out the nipple
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| lymphatic drainage in the chest area is split between the axial and intramammary system how? | 75% axial and 25% intramammary
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| what is the inner layer of the breast | ductal and lobular layer cuboid shape
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| outer layer of the breast | myoepithelial with spindle shape
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| what happens at puberty | lobular units are developing
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| what happens during a menstral cycle | proliferation of the lobules with vaculozation during the luteal phase after ovulation
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| what happens to the lobule during pregnancy | pronounced lobules with incresed vaculization with distended lumens
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| what happens to the lumen post menopause | lobar atrophy and incresed fat
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| what are the three ways to scan the breast | Physical exam, Mammography, Biopsy
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| what can you see with mammography | mass, microcalcifications (also in benign), assymetry
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| what can you see with biopsy | invasive vs. non-invasive
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| Can biopsy be therapeutic | yes if it is excisional but may need surgery and or radiation
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| what is the most common malignancy | breast cancer
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| what is the number 2 cause of cancer death in women | breastcancer
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| what is the median age to get cancer | 50
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| Risk factors of breast cancer | family, genetics, hormones, radiation, proliferative disesae, dietary fat
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| what percent of breast cancers are inherited | 5%
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| what percent of inherited breast cancers are BRCA1 and 2 | 70%
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| how do hormones play a role in the development of breast cancer | early menarche, late menopause, late age of 1st pregnancy
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| how long is the latent period of radiation | 10-15 years
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| what are the proliferative breast disseases | Fibrocystic change, ductal hyperplasia and radial scar
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| where are most mets and spreads | spread to axial, internal mammary, and supraclavicular nodes
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| where are some common distal sites of spreading breast cancer | skeletal muscles, lungs, CNS
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| what is the prognosis of breast cancer based on | TMN
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