DD
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Lancefield groups of medical importance | A, B, and D
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| Group based on | Lancefield
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| Type based on | M protein
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| fun of M protein | antigenic determinant but also antigenic
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| Streptolysin O | Antigenic responsible for damage to cardiac and Red blood cells
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| Streptolysin S | O2 stable not antigenic
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| Capsule? | hyaluronic acid capsule non-immunogenic
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| Pyrogenic Exotoxin | Spe A, B, C
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| What Exotoxin causes Scarlet fever? | Spe A
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| What exotoxin causes TSLS | Spe A
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| What Ag causes necrotizing fascilitis | Spe B
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| what M protein is associated with TSLS | M1
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| what M proteins are associated with Acute Rheumatic Fever | 2, 4, 12
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| what is Strep sensitive to | Bacitracin
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| how can you diagnose strep | Catalase neg, bacitracin sensitive, rapid agglutination, B hemolytic, ASO (abs to streptolysin O)
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| what does M protein do? | antiphagocytic it binds fibrinogen (host) and protein H to stop complement
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| Random assistant exotoxins | Hyaluronidase, DNAase, Anti C5 peptidase
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| how long do symptoms of Strep pharyngitis last | 7 days
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| how long are strep pharyngitis kids contagious | 1-4 weeks
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| how does necrotizing fasciitis enter | trauma
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| mortality from necrotizing faciitis Hospital gangrene | 60%
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| how does scarlet fever present | starts on trunk and spreads to extremities
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| how does TSS and TSLS differ | with TSLS pts are bacteremic
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| what percent dev. chorea with Rheumatic fever | 6%
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| Acute migratory polyarthritis | in 75% no permanent damage
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| when does Post strep GN show up | 10 days after skin or pharyngiitis
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| What effect can TSLS have on the lungs | ARDS
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| mortality of TSLS | 30%
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| Treat Strep | penicillin V or erythromycin, Penicillin G for serious infections
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