Cardio Drugs
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| ADR of ACE inhibitors [CHF drugs] [vasodilator] | dry irritating cough because of bradykinin
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| Angiotensin Receptor Blockers (ARBs) gives no cough because [CHF drugs] [vasodilator] | no bradykinin effect
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| ADR of quinidine [anti-arrhythmia drugs] [Na+ block] | Torsades du Pointes, cinchonism (constipation/diarrhea, tinnitus)
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| ADR of Amiodarone [anti-arrhytmia drugs] [K+ block] | smurf skin, thyroid dysfunction
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| Lidocaine is DOC for [anti-arrhytmia drugs] [Na+ block] | post-MI
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| ADR of Verapamil [anti-arrhytmia drugs] [Ca+ block] | AV block
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| Adenosine is DOC for [anti-arrhytmia drugs] [unclassified] | PSVT and AV nodal arrhythmias
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| Nitrates decrease pre-load by ______ and has an ADR of ______ [angina drugs] | dilating veins; flushing and postural HTN
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| Nitroglycerine is DOC for [angina drugs] | acute angina
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| Verapamil is contraindicated in [angina drugs] [Ca+ block] | patient with CHF or AV block
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| What does Niacin do, and what is it's ADR? [anti-hyperlipidemic drugs] | decreases LDL, increases HDL, causes gout
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| Fibrates (have fibr in name) mixed with statins cause what? [anti-hyperlipidemic drugs] | myopathy
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| What does Propanolol do, and what is it's contraindications? [anti-hypertensive drugs] [adrenergic antagonist] | reflex peripheral vasoconstriction; CI in prinzmetal angina, asthma, COPD, diabetics
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| Methyldopa is the DOC for ________ [anti-hypertensive drugs] [adrenergic agonists] | hypertension in pregnancy
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| What should you not prescribe with Verapamil? [anti-hypertensive drugs] [Ca+ block] | beta-blockers, it causes cardiac arrest
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| What does Nitroprusside do? [anti-hypertensive drugs] [direct-acting vasodilator] | vasodilates arteries and veins by releasing NO and cyanide ions, DOC for hypertensive emergency
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| Carbonic anhydrase inhibitors can be used for ______ and their MOA is _______ [anti-hypertensive drugs] [diuretics] | Acute mountain sickness prophylaxis; inhibits Na-H antiport
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| What are loop diuretics (sulfonamides/Furosemide) the DOC for, and what is their MOA? [anti-hypertensive drugs] [diuretics] | Acute pulmonary edema in heart failure patients; inhibits Na/K/2Cl transport
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| ADR of Furosemide [anti-hypertensive drugs] [diuretics] | hypocalcemia, ototoxicity
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| ADR of Spironolactine and its MOA [anti-hypertensive drugs] [K+ sparing diuretics] | anti-androgen effects, peptic ulcer; aldosterone antagonist
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