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The Integumentary System

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Term
Definition
cutaneous   Pertaining to the skin (from Latin cutis, meaning "skin")  
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derma   Skin (from Greek)  
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dermis   The layer of the skin between the epidermis and the subcutaenous tissue; the true skin or corium  
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epidermis   The outermost layer of the skin (from epi-, meaning "upon or over" and derm, meaning "skin")  
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hair   A thread-like keratinized outgrowth from the skin (root: trich/o)  
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hair follicle   The sheath in which a hair develops  
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integumentary system   The skin and its associated glands, hair, and nails  
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keratin   A protein that thickens and toughens the skin and makes up hair and nails (root: kerat/o)  
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melanin   A dark pigment that gives color to the hair and skin and protects the skin against the sun's radiation (root: melan/o)  
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nail   A plate-like keratinized outgrowth of the skin that covers the dorsal surface of the terminal phalanges (root: onych/o)  
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sebaceous gland   A gland that produces sebum; usually associated with a hair follicle (root: seb/o)  
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sebum   A fatty secretion of the sebaceous glands that lubricates the hair and skin (root: seb/o)  
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skin   The tissue that covers the body; the integument (roots: derm/o, dermat/o)  
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subcutaneous layer   The layer of tissue beneath the skin; also called hypodermis  
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sudoriferous gland   A sweat gland (root: hidr/o)  
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derm/o, dermat/o   skin  
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kerat/o   keratin, horny layer of the skin  
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melan/o   dark, black, melanin  
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hidr/o   sweat, perspiration  
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seb/o   sebum, sebaceous gland  
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trich/o   hair  
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onych/o   nail  
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bulla   raised, fluid-filled lesion larger than a vesicle (plural: bullae)  
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fissure   crack or break in the skin  
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macule   flat, colored spot  
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nodule   solid, raised lesion larger than a papule; often indicative of systemic disease  
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papule   small, circular, raised lesion at the surface of the skin  
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plaque   superficial, flat, or slightly raised differentiated patch more than 1 cm in diameter  
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pustule   raised lesion containing pus; often in a hair follicle or sweat pore  
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ulcer   lesion resulting from destruction of the skin and perhaps subcutaneous tissue  
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vesicle   small, fluid-filled, raised lesion; a blister or bleb  
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wheal   smooth, rounded, slightly raised area often associated with itching; seen in urticaria (hives), such as that resulting from allergy  
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atopic dermatitis   Hereditary, allergic, chronic skin inflammation with pruritus (itching); eczema  
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basal cell carcinoma   An epithelial tumor that rarely metastasizes and has a high cure rate with surgical removal  
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cicatrization   The process of scar formation; a scar is a cicatrix  
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debridement   Removal of dead or damaged tissue, as from a wound  
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dehiscence   Splitting or bursting, as when the layers of a wound separate  
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dermatitis   Inflammation of the skin, often associated with redness and itching; may be caused by allergy, irritants (contact dermatitis), or a variety of diseases  
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dermatology   Study of the skin and diseases of the skin  
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dermatome   Instrument for cutting thin skin sections for grafting  
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eczema   A general term for skin inflammation with redness, lesions, and itching; atopic dermatitis  
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erythema   Diffuse redness of the skin  
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escharotomy   Removal of scab tissue resulting from burns or other skin injuries; a scab or crust is an eschar  
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evisceration   Protrusion of internal organs (viscera) through an opening, as through a wound  
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exudate   Material, which may include fluid, cells, pus, or blood, that escapes from damaged tissue  
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Kaposi sarcoma   Cancerous lesion of the skin and other tissues seen most often in patients with AIDS  
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keloid   A raised, thickened scar caused by tissue overgrowth during scar formation  
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lupus erythematosus (LE)   A chronic, inflammatory, autoimmune disease of connective tissue that often involves the skin; types include the more widespread systemic lupus erythematosus (SLE) and a discoid form (DLE) that involves only the skin  
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malignant melanoma   A metastasizing pigmented skin tumor  
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pemphigus   An autoimmune disease of the skin characterized by sudden, intermittent formation of bullae (blisters); may be fatal if untreated  
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pressure ulcer   An ulcer caused by pressure to an area of the body, as from a bed or chair; decubitus ulcer, bedsore, pressure sore  
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pruritus   Severe itching  
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psoriasis   A chronic hereditary dermatitis with red lesions covered by silvery scales  
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rule of nines   A method for estimating the extent of body surface area involved in a burn by assigning percentages in multiples of nine to various body regions  
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scleroderma   A chronic disease that is characterized by thickening and tightening of the skin and that often involves internal organs in a form called progressive systemic sclerosis (PSS)  
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squamous cell carcinoma   An epidermal cancer that may invade deeper tissues but tends not to metastasize  
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acne   An inflammatory disease of the sebaceous glands and hair follicles usually associated with excess sebum secretion; acne vulgaris  
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actinic   Pertaining to the effects of radiant energy, such as sunlight, ultraviolet light, and x-rays  
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albinism   A hereditary lack of pigment in the skin, hair, and eyes  
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alopecia   Absence or loss of hair; baldness  
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Beau lines   White lines across the fingernails; usually a sign of systemic disease or injury  
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bromhidrosis   Sweat that has a foul odor because of bacterial decomposition; also spelled bromidrosis  
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carbuncle   A localized infection of the skin and subcutaneous tissue, usually caused by staphylococcus, and associated with pain and discharge of pus  
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comedo   A plug of sebum, often containing bacteria, in a hair follicle; a blackhead (plural: comedones)  
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dermatophytosis   Fungal infection of the skin, especially between the toes; athlete's foot (root phyt/o means "plant")  
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diaphoresis   Profuse sweating  
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dyskeratosis   Any abnormality in keratin formation in epithelial cells  
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ecchymosis   A collection of blood under the skin caused by leakage from small vessels  
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erysipelas   An acute infectious skin disease with localized redness and swelling and systemic symptoms  
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erythema nodosum   Inflammation of subcutaneous tissues resulting in tender, erythematous nodules; may be an abnormal immune response t a systemic disease, an infection, or a drug  
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exanthema   Any cutaneous eruption that accompanies a disease, such as measles; a rash  
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excoriation   Lesion caused by scratching or abrasion  
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folliculitis   Inflammation of a hair follicle  
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furuncle   A painful skin nodule caused by staphylococci that enter through a hair follicle; a boil  
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hemangioma   A benign tumor of blood vessels; in the skin, called birthmarks or port wine stains  
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herpes simplex   A group of acute infections caused by herpes simplex virus; type I herpes simplex virus produces fluid-filled vesicles, usually on the lips, after fever, sun exposure, injury, or stress; type II infections usually involve the genital organs  
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hirsutism   Excessive growth of hair  
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icthyosis   A dry, scaly condition of the skin (from the root ichthy/o, meaning "fish")  
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impetigo   A bacterial skin infection with pustules that rupture and form crusts; most commonly seen in children, usually on the face  
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keratosis   Any skin condition marked by thickened or horny growth; seborrheic keratosis is a benign tumor, yellow or light brown in color, that appears in the elderly; actinic keratosis is caused by exposure to sunlight and may lead to squamous cell carcinoma  
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lichenification   Thickened marks caused by chronic rubbing, as seen in atopic dermatitis (a lichen is a flat, branching type of plant that grows on rocks and bark)  
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mycosis fungoides   A rare malignant disease that originates in the skin and involves the internal organs and lymph nodes; there are large, painful, ulcerating tumors  
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nevus   A defined discoloration of the skin; a congenital vascular skin tumor; a mole, birthmark  
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paronychia   Infection around a nail caused by bacteria or fungi; may affect multiple nails  
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pediculosis   Infestation with lice  
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petechiae   Flat, pinpoint, purplish-red spots caused by bleeding within the skin or mucous membrane (singular: petechia)  
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photosensitization   Sensitization of the skin to light, usually from the action of drugs, plant products, or other substances  
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purpura   A condition characterized by hemorrhages into the skin and other tissues  
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rosacea   A condition of unknown cause involving redness of the skin, pustules, and overactivity of sebaceous glands, mainly on the face  
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scabies   A highly contagious skin disease caused by a mite  
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senile lentigines   Brown macules that appear on sun-exposed skin in adults; liver spots  
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shingles   An acute eruption of vesicles along the path of a nerve; herpes zoster; caused by the same virus that causes chickenpox  
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tinea   A fungal skin infection; ringworm  
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tinea versicolor   Superficial chronic fungal infection that causes varied skin pigmentation  
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urticaria   A skin reaction marked by temporary, smooth, raised areas (wheals) associated with itching, hives; see also wheals  
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venous stasis ulcer   Ulcer caused by venous insufficiency and stasis of venous blood; usually forms near the ankle  
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verruca   An epidermal tumor; a wart  
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vitiligo   Patchy disappearance of pigment in the skin; leukoderma  
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xeroderma pigmentosum   A fatal hereditary disease that begin in childhood with skin discolorations and ulcers and muscle atrophy; there is increased sensitivity to the sun and increased susceptibility to cancer  
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aloe   A gel from leaves of the plant Aloe vera that is used in treatment of burns and minor skin irritations  
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antipruritic   Agent that prevents or relieves itching  
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cautery   Destruction of tissue by physical or chemical means; cauterization; also the instrument or chemical used for this purpose  
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dermabrasion   A plastic surgical procedure for removing scars or birthmarks by chemical or mechanical destruction of epidermal tissue  
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dermatoplasty   Transplantation of human skin; skin grafting  
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diascopy   Examination of skin lesions by pressing a glass plate against the skin  
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fulguration   Destruction of tissue by high-frequency electric sparks  
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skin turgor   Resistance of the skin to deformation; evidenced by the ability of the skin to return to position when pinched; skin turgor is a measure of the skin's elasticity and state of hydration  
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Wood lamp   An ultraviolet light used to diagnose fungal infections  
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BSA   Body surface area  
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DLE   Discoid lupus erythematosus  
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FTSG   Full-thickness skin graft  
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LE   Lupus erythematosus  
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PSS   Progressive systemic sclerosis  
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PUVA   Psoralen ultraviolet A  
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SCLE   Subacute cutaneous lupus erythematosus  
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SLE   Systemic lupus erythematosus  
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SPF   Sun protection factor  
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STSG   Split-thickness skin graft  
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UV   Ultraviolet  
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UVA   Ultraviolet A  
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UVB   Ultraviolet B  
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VAC   Vacuum-assisted closure  
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