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Med Term CH6 Lymphatic and Immune

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Question
Answer
anti-   against  
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carcin/o   cancerous  
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immun/o   immune, protection, safe  
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lymph/o   lymph, lymphatic tissue  
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lymphaden/o   lymph node or gland  
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lymphangi/o   lymph vessel  
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neo-, ne/o   new, strange  
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-oma   tumor, neoplasm  
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onc/o   tumor  
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phag/o   eat, swallow  
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-plasm   formative material of cells  
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sarc/o   flesh, connective tissue  
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splen/o   spleen  
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-tic   pertaining to  
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tox/o   poison, poisonous  
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3 main functions of lymphatic system   1) absorb fat/ fat-soluble vit's through lacteals of sm intestine 2) remove waste products from tissues & cooperate w/ immune system in destroying invading pathogens 3) return filtered lymph to veins @ base of neck  
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food digested here   small intestine  
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villi   fingerlike projections that line small intestine that contain lacteals and blood vessels  
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lacteals   specialized structures of lymphatic system that absorb fats that cannot be transported by bloodstream.  
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blood vessels of villi absorb   nutrients, fats, & fat-soluble vitamins from digested food directly into blood stream for use throughout the body.  
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interstitial fluid   aka intercellular or tissue fluid, plasma from arterial blood that flows out of arterioles & into capillaries, then into spaces btw cells of tissues  
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Interstitial fluid delivers   nutrients, oxygen, & hormones to cells  
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When interstitial fluid leaves cells   brings w/ it waste products & protein molecules created w/in cells. 90% of fluid returns to bloodstream  
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lymph   made of of remaining 10% of returning interstitial fluid. Clear, watery fluid containing electrolytes & proteins.  
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lymph collects   protein molecules created w/in cells as it leaves. Removes dead cells, debris, & pathogens from intercellular spaces  
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lymph enters   very small capillaries w/in tissues then flows into progressively larger vessels & ducts as it travels upward toward neck  
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lymph plays an active role in cooperation with the______   immune system to protect the body against invading microorganisms & diseases.  
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lymphatic circulatory system works closely together with   blood circulatory system, so sometimes called secondary circulatory system  
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lymphatic system depends on ____ to move fluid   pumping motion of muscles  
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lymph flows in ______ direction   one. From point of origin can only move upward until returns to circulatory system at base of neck.  
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blood is filtered by the _______ and waste products are excreted by the _______   kidneys / urinary system  
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lymph is filtered by _______   lymph nodes, which are located along lymphatic vessels & contain specialized cells of the immune system  
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lymphatic capillaries   microscopic, blind-ended (sealed on one end) tubes located near surface of body w/ capillary walls only 1 cell in thickness  
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lymphatic vessels   progressively larger vessels where the lymph flows from the capillaries. Deeper w/in tissues. Valves to prevent backflow.  
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right lymphatic duct   collects lymph from rt side of head/ neck, upper rt quadranct & rt arm. Empties into rt subclavian vein.  
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subclavian vein   proximal part of main vein of arm  
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thoracic duct   largest lymphatic vessel in body, collects lymph from LT side of head & neck, upper LT quad of trunk, LT arm, & entire lower portion of trunk, &both legs. Empties into LT subclavian vein  
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lymph node   small, bean-shaped, contains specialized lymphocytes capable of destroying pathogens. 400-700 along LG lymphatic vessels. 1/2 in abdomen  
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lymphocytes   aka lymnphoid cells, destroy harmful substances such as bacteria, viruses, & malignant cells.  
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cervical lymph nodes   located along the sides of the neck  
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axillary lymph nodes   located under arms in armpits  
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inguinal lymph nodes   located in inguinal (groin) area of lower abdomenb  
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lymphocytes   aka lymphoid cells, leukocytes formed in bone marrow as stem cells. Defend body against antigens  
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antigen   any substance that the body regards as being foreign. Viruses, bacteria, toxins, transplanted tissue  
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3 types of lymphocytes   natural killer cells, B cells, & T cells  
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lymphocytes do this in lymphoid tissues throughout body   undergo maturation & differentiation  
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lymphocyte maturation   process of becoming mature  
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lymphocyte differentiation   to be modified to perform a specific function. Become specialized antibodies capable of attacking specific antigens  
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natural killer cells   aka NK cells, play important role in killing of cancer cells & cells infected by viruses  
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B cells   aka B lymphocytes, specialized that produce antibodies to destroy a specific antigen.  
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B cells most effective against   viruses & bacteria that are circulating in the blood.  
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When does B cell transform into plasma cell?   when confronted w/ the antigen, secrete large volume of antibodies coded to destroy specific antigens  
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T cells   aka T lymphocytes, origin thymus. Play central role in cell-mediated immunity  
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cytokines   group of proteins such as interferons & interleukins released primarily by T cells.  
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interferons, why produced   produced in response to presence of antigens, particularly viruses or tumor cells.  
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interferons do this   activate immune system, fight viruses by slowing or stopping multiplication, & signal other cells to increase defenses.  
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lymphoid   pertaining to the lymphatic system or resembling lymph or lymphatic tissue or resembling lymph/ lymphatic tissue  
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primary roles of lymphoid are in conjunction with the   immune system  
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tonsils   3 masses of lymphoid tissue that form a protective ring around the back of the nose & upper throat  
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tonsils play an important role in the immune system by...   preventing pathogens from entering the respiratory system when breathing through the nose & mouth  
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adenoids   aka nasopharyngeal tonsils, located in nasopharynx, which is upper part of pharynx  
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palatine tonsils   located on LT & RT sides of throat in area that is visible @ back of mouth  
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palatine   hard & soft palates that form the roof of the mouth  
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lingual tonsils   located @ base of tongue but not readily visible  
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lingual   pertaining to the tongue  
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thymus   mass of lymphoid tissue located above heart, reaches greatest size @ puberty & becomes smaller w/ age  
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thymus secretes   a hormone that stimulates the maturation of lymphocytes into T cells, as part of endocrine system  
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T cells in thymus   essential to immune system & leave thymus through the bloodstream & the lymphatic system  
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vermiform appendix   aka appendix, hangs from lower portion of cecum - may play important role in immune system  
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cecum   1st section of large intestine  
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spleen   sac-like mass of lymphoid tissue located in LT upper quad of abdomen, just inferior to diaphragm & posterior to stomach  
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what does spleen do?   filters microorganisms & foreign material from blood. Forms lymphocytes & monocytes for immune system  
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These are specialized leukocytes found in spleen   lymphocytes & monocytes  
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type of function from spleen   hemolytic function of destroying worn-out erythrocytes & releasing their hemoglobin for reuse  
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Spleen stores/ maintains   extra erythrocytes & maintains appropriate balance btw these cells & plasma of blood  
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primary function of immune system   maintain good health & to protect body from harmful substances  
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Harmful substances the immune system protects body from   pathogens, allergens, toxins, malignant cells  
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pathogens   disease-producing microorganisms  
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allergens   substances that produce allergic reactions  
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toxins   poisonous or harmful substances  
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malignant cells   potentially life-threatening cancer cells  
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Unlike other body systems, the immune system is not....   contained w/in a single set of organs or vessels. Instead, its functions use structures from several other body systems  
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1st lines of defense for immune system   intact skin, respiratory system, digestive system, lymphatic system  
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intact skin   wraps body in physical barrier to prevent invading organisms from entering body  
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intact   means that there are no cuts, scrapes, open sores, or breaks in the skin.  
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acid mantle   skin is covered in this & it makes it inhospitable environment for most bacteria  
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respiratory system (w/ immune)   traps breathed-in foreign matter w/ nose hairs & moist mucous membrane lining of respiratory system. Coughing/ sneezing  
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digestive system   uses acids & enzymes produced by stomach to destroy invaders that are swallowed or consumed w/ food  
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lymphatic system structures   work together in specific ways to attack & destroy pathogens that have succeeded in entering the body  
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antigen-antibody reaction   aka immune reaction, involves binding antigens to antibodies. Labels dangerous antigen to be recognized/ destroyed  
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tolerance   an acquired unresponsiveness to a specific antigen.  
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Immuniglobin G   IgG, most abundant antibodies, in blood serum & lymph, active against bacteria-fungi-viruses-foreign particles  
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Immuniglobin A   IgA, antibodies against ingested antigens, found in body secretions saliva-sweat-tears, function to prevent attachment of viruses & bacteria to epithelial surfaces that line most organs  
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Immuniglobin M   IgM, antibodies found in circulating body fluids, 1st antibodies to appear in response to initial exposure or antigen  
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Immuniglobin D   IgD, antibodies found only on surface of B cells, important in B cell activation  
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Immuniglobin E   IgE, class of antibodies produced in lungs-skin-mucous membranes, responsible for all allergic reactions.  
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antibody   disease-fighting protein created by immune system in response to presence of specific antigen  
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antibody/ immunnoglobulin   often used interchangeably  
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immunoglobins   bind w/ specific antigens in antigen-antibody response. 5 primary: G, A, M, D, E, secreted by plasma cells  
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phagocytes   specialized leukocytes act as part of antigen-antibody reaction by destroying cell debris, dust, pollen, pathogens by phagocytosis  
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phagocytosis   process of destroying pathogens by surrounding & swallowing them.  
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Phagocytes include:   monocytes, macrophages, dendritic cells, & mast cells  
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monocytes   leukocytes that provide immunological defenses against many infectious organisms. Replenish macrophages & dendritic cells  
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macrophage   derived from monocytes after leave bloodstream & enter tissue. WBC that surrounds & kills invading cells. Remove dead cells & stimulate action of other immune cells  
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dendritic cells   specialized WBC's that patrol body searching for antigens that produce infections. Grabs it, swallows it, & alerts B & T cells  
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complement system   group of proteins that normally circulate in blood in an inactive form. Complement ability of antibodies when needed  
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complement   to complete or make whole  
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immunity   state of being resistant to a specific disease. Natural or acquired  
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natural immunity   aka passive immunity, resistance to disease present w/o administration of an antigen or exposure to disease.  
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natural immunity is present at...   birth & can be augmented when breast milk passes from nursing mother to baby.  
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acquired immunity   obtained by having had a contagious disease.  
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vaccinated   provides protection against a contagious disease w/o having been exposed to the risk of actually having the disease  
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vaccine   preparation containing an antigen, consisting of whole or partial disease-causing organisms which are killed or weakened  
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vaccination   provides protection against disease. Some need periodic booster  
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allergist   specializes in diagnosing & treating conditions of altered immunologic reactivity, such as allergic reactions  
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immunologist   specializes in diagnosing & treating disorders of the immune system  
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lymphologist   physician who specializes in diagnosing & treating disorders of lymphatic system.  
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oncologist   physician who specializes in diagnosing & treating malignant disorders such as tumors & cancer  
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lymphadenitis   aka swollen glands, inflammation of lymph nodes, frequent indication of infection  
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lymph nodes/ lymph glands   used interchangeably  
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lymphadenopathy   any disease process affecting a lymph node or nodes  
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lymphangioma   benign tumor formed by an abnormal collection of lymphatic vessels due to a congenital malformation of lymphatic system  
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ruptured spleen   medical emergency that occurs when the covering of the spleen is torn, usually from blow to abdomen  
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splenorrhagia   bleeding from spleen  
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splenomegaly   abnormal enlargement of spleen. Can be due to bleeding from injury, infectious disease, or abnormal functioning of immune s  
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lymphoscintigraphy   diagnostic test performed to detect damage or malformations of lymphatic vessels. Radioactive substance injected into ducts  
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lymphedema   swelling of the tissues due to abnormal accumulation of lymph fluid w/in the tissues - damage preventing lymph from draining  
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primary lymphedema   hereditary condition of lymphatic system that develops w/ swelling in feet, then ankles, & upward. Frequent- females  
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secondary lymphedema   damage to lymphatic vessels most frequently due to cancer treatment, surgery, trauma, or burns  
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primary/ secondary lymphedema treatment   compression/ exercise to control swelling & minimize infections. cannot be cured  
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bioimpedance spectroscopy   noninvasive method of diagnosing lymphedema. Measures resistance to an electrical current passed through limb  
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effectiveness of immune system depends on individual's:   General health, age, heredity  
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Age and the immune system   older have more acquired immunity but responds slower to new challenges. Babies & young little acquired immunity.  
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heredity and the immune system   genes & genetic disorders affect the individual's general health & functioning  
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allergy   aka hypersensitivity, overreaction by body to a particular antigen.  
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allergen   substance that produces an allergic reaction to an individual  
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localized allergic response   aka cellular response, includes redness-itching-burning where skin is in contact w/ allergen. More exposure = more severe  
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systemic reaction   aka anaphylaxis or anaphylactic shock, severe response to an allergen. Develop quickly & can die w/in minutes  
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scratch test   diagnostic test to ID commonly troublesome allergens such as tree pollen. Swelling/ itching indicate allergy  
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allergen-specific immunoglobulin E   IgE, blood test can determine substance allergy  
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antihistamines   medications administered to relieve or prevent symptoms of allergies. Prevent the histamine  
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histamine   substance produced by the body that causes the itching, sneezing, runny nose, & watery eyes of allergic reaction  
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autoimmune disorder   aka autoimmune disease, any of a large group of diseases characterized by condition in which immune system produces antibodies against its own tissues  
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% of Americans w/ autoimmune disorder   3% of Americans w/ women affected 2.7 x's more than men. Affect most body systems.  
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immunodeficiency disorder   occurs when the immune response is compromised  
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compromised   weakened or not functioning properly  
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severe combined immunodeficiency   SCID, inherited condition which abnormalities in immune system cause increased susceptibility to infection & failure to thrive as result of infections  
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Rheumatoid Arthritis   affects joints & connective tissue of skeletal system  
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Myasthenia gravis   affects nerve & muscle synapses of muscular system  
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Pernicious anemia   affects RBC's of cardiovascular system  
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Crohn's disease   affects intestines, ileum, or colon of the digestive system  
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multiple sclerosis   affects the brain & spinal cord of the nervous system  
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scleroderma   affects the skin & connective tissues of the integumentary system  
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Graves' disease   affects the thyroid gland of the endocrine system  
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Human immunodeficiency virus   HIV, bloodborne infection where virus damages or kills T cells of immune system, causing it to progressively fail.  
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opportunistic infection   caused by pathogen that does not normally produce an illness in healthy humans. When host debilitated, causes infection  
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debilitated   weakened by another condition  
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acquired immunodeficiency syndrome   AIDS, most advanced & fatal stage of an HIV infection  
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Treatment for HIV   regimen of antiretroviral drugs "cocktail" b/c must be taken in combination w/ ea other. Help control impact of disease.  
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Kaposi's sarcoma   opportunistic infection frequently assoc. w/ HIV. Cancer causes patches of abnormal tissue to grow under skin in mouth, nose, throat or other organs  
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ELISA   acronym for enzyme-linked immunosorbent assay, blood test used to screen for HIV antibodies, Lyme disease, & others  
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western blot test   blood test that is more accurate than ELISA, confirms diagnosis when positive ELISA.  
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Pathologies associated w/ AIDS Central Nervous System (CNS)   Meningitis, Encephalitis, AIDS dementia  
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Pathologies associated w/ AIDS Tumors   Lymphoma  
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Pathologies associated w/ AIDS Large Intestine   Colitis  
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Pathologies associated w/ AIDS Mouth   Herpes labialis, Oral thrush  
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Pathologies associated w/ AIDS Lung   Pneumonia  
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Pathologies associated w/ AIDS Kidney   AIDS nephropathy  
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Pathologies associated w/ AIDS Small Intestine   Malabsoption  
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Pathologies associated w/ AIDS Skin   Dermatitis, Folliculitis, Impetigo, Kaposi's sarcoma  
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immunotherapy   aka biological therapy, disease treatment that involves either stimulating or repressing immune response  
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stimulate   cause greater activity  
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repress   decrease or stop a normal response  
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Immunotherapy in treatment of cancers   used to stimulate the immune response to fight malignancy  
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immunotherapy in treatment of allergies   aka allergy desensitization, used to repress the body's sensitivity to a particular allergen.  
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synthetic immunoglobulins   aka immune serum, used as post-exposure preventative measure against certain viruses, including rabies & some hepatitis  
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post-exposure   patient has been exposed to virus, goal is to prevent disease from developing by providing temp immunity  
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synthetic interferon   used in treatment of multiple sclerosis, hep C, & some cancers  
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monoclonal antibodies   any of a class of antibodies artificially produced in lab by identical offspring of a clone of specific cells. Enhance immune response.  
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monoclonal   pertaining to a single clone of cells  
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clone   an exact replica of a group of bacteria  
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immunosuppression   treatment to repress or interfere w/ ability of the immune system to respond to stimulation by antigens.  
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immunosuppressant   substance that prevents or reduces body's normal immune response. Meds to prevent donor rejection  
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corticosteroid drug   hormone-like preparation administered primarily as an anti-inflammatory & immunosuppressant.  
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cytotoxic drug   medication that kills or damages cells. Used as immunosuppressants or antineoplastics.  
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pathogen   microorganism that causes a disease in humans  
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microorganism   living organism that is so small it can only by seen w/ aid of microscope  
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pathogenic   capable of producing disease  
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bacteria   one-celled microscopic organisms. Most not harmful  
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bacilli   rod-shaped, spore-forming bacteria  
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anthrax   contagious disease that can be transmitted through livestock infected w/ bacillus anthracis, in labs for biological warfare  
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rickettsia   small bacterium that lives in lice, fleas, ticks, mites  
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Rocky Mountain spotted fever   caused by a rickettsia that is transmitted to humans by bite of infected tick  
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spirochetes   long, slender, spiral-shaped bacteria that have flexible walls & are capable of movement  
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Lyme disease comes from   LIME, transmitted to humans by tick bite that has had contact w/ deer infected w/ spirochete borrelia burgdorferi  
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Lyme disease symtoms   fever, headache, fatigue, skin rash known as erythema migrans. Untreated can spread to joints, heart, CNS.  
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Lyme disease name comes from   First diagnosed in Old Lyme, Connecticut  
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Syphilis is also caused by...   spirochetes  
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staphylococci   group of approx 30 species of bactera that form irregular groups or clusters resembling grapes. Most harmless, on skin/ mucous.  
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staphylococcus aureus   aka staph aureus, form of staph that infects wounds & causes serious problems like TSS or food poisoning  
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streptococci   bacteria that form a chain. Most harmless, but can cause strep throat, meningitis, endocarditis, necrotizing fasciitis  
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strept/o   twisted chain  
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-cocci   spherical bacteria  
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antibiotic-resistant bacteria   occur when antibiotics fail to kill all of the bacteria they target. Surviving bacteria resistant to drug. Can be severe/ fatal.  
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methicillin-resistant Staphylococcus aureus   MRSA, resistant to most antibiotics, small red bumps w/ black top that become abscesses, serious or fatal  
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fungus   simple parasitic organism, some harmless some pathogenic  
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tinea pedis   aka athlete's foot, fungal infection that develops btw toes  
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yeast   type of fungus  
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candidiasis   aka yeast infection, occur on skin or mucous mem. in warm, moist areas like vagina or mouth - from Candida albicans  
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oral thrush   yeast infection that occurs in mouth  
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vaginal candidiasis   yeast infection that occurs in vagina  
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parasite   plant or animal that lives on or w/in another living organism at expense of that organism  
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malaria cause   caused by a parasite that lives in certain mosquitoes & transferred to humans by bite.  
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malaria symtoms   develop in 1-4 wks from infection: fever, shaking, chills, headache, muscle aches, fatigue.  
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infections from parasites   malaria, toxoplasmosis  
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toxoplasmosis   parasite transmitted from pets to humans w/ contaminated feces.  
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toxoplasmosis & pregnancy   cause disease in developing child like microcephalus or hydrocephalus  
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microcephalus   abnormally small head & underdeveloped brain  
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hydrocephalus   excess cerebrospinal fluid accumulates in ventricles of brain  
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infections from viruses   Ebola, influenza, measles, mumps, rubella, rabies, west nile virus,  
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viruses   very small infectious agents that live only by invading other cells. After invasion, reproduces & releases newly formed virus & spreads  
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Ebola cause   rare & generally fatal disease transmitted by contact w/ any bodily fluids contaminated.  
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Ebola symptoms   appear 21 days from exposure: high fever, vomiting, diarrhea. Later: massive internal bleeding & organ failure  
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influenza cause   aka flu, highly contagious viral respiratory infection typically seasonal epidemics. Vaccine can protect.  
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influenza symptoms   fever, sore throat, muscle aches, cough, runny nose, fatigue. Complications: pneumonia.  
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measles cause   acute, highly contagious infection transmitted by respiratory droplets of the rubeola virus  
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measles symptoms   red, itchy rash over entire body, high fever, runny nose, coughing. Complications photophobia  
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photophobia   severe sensitivity to light  
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mumps   actue viral infection w/ swelling of parotid glands, can also cause painful swelling of ovaries or testicles  
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parotid glands   salivary glands located just in front of ears  
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rubella   aka German measles, 3-day measles. Viral infection w/ low-grade fever, swollen glands, inflamed eyes, & fine pink rash.  
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Rubella and pregnancy   can cause defects in developing fetus  
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rabies cause   acute viral infection transmitted to humans from bite or saliva of infected animal. Need immediate treatment  
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rabid   animal infected w/ rabies  
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rabies symtoms   untreated, 30-90 days after infection almost always fatal.  
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west nile virus cause   spread to humans by bite of an infected mosquito  
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west nile virus symtoms   mild = flu-like, severe=spreads to spinal cord & brain.  
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Flavivirus genus   West Nile virus and viruses that cause the mosquito-borne tropical disease dengue fever  
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Infections from Herpesviruses   cytomegalovirus, varicella, herpes zoster, infectious mononucleosis, Epstein-Barr, herpes simplex  
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cytomegalovirus   found in most body fluids, silent infection w/ no signs or symptoms, but serious if weakened immune system or transmitted to unborn child - disabilities  
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varicella cause   aka chickenpox, caused by herpes virus varicella zoster & highly contagious.  
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varicella symptoms   fever & rash consisting of hundreds of itchy, fluid-filled blisters that burst & form crusts.  
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herpes zoster   aka shingles, acute viral infection characterized by painful skin eruptions that follow the underlying route of inflamed nerve  
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postherpetic neuralgia   complication that may follow herpes zoster if nerve fibers have been damaged during outbreak. Persistent & severe pain  
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infectious mononucleosis   aka mono, caused by Epstein-Barr virus. Fever, sore throat, enlarged lymph nodes. Sometimes swelling of spleen/ liver  
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antibiotics   medications capable of inhibiting growth or killing pathogenic bacterial microorganisms. Effective for bacterial infections  
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inhibit   slow the growth or development  
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antibiotics are not effective against this type of infection   viral  
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antibiotics are effective against this type of infection   bacterial  
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bactericide   substance that causes death of bacteria, antibiotics include penicillins and cephalosporins  
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bacteriostatic   agent slows or stops the growth of bacteria, antibiotics include tetracycline, sulfonamide, & erythromycin  
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antifungal   agent that destroys or inhibits growth of fungi, antifungal ex is Lotrimin, known as an antimycotic  
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antiviral drug   used to treat viral infections or to provide temporary immunity, ex is acyclovir.  
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oncology   study of the prevention, causes, & treatment of tumors & cancer.  
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Cancer names & deaths in US   most named for part of body where originated, can attack all systems, 2nd leading cause of death in US behind heart disease  
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tumor   aka neoplasm, abnormal growth of body tissue. w/in the mass multip of cells is uncontrolled, abnormal, rapid, progressive  
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benign tumor   not a form of cancer, & not life-threatening. Can cause damage as it grows to adjacent structures  
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benign   not life-threatening  
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malignant tumor   form of cancer capable of spreading to distant body sites or systems, & potentially life-threatening.  
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malignant   becoming progressively worse & life-threatening  
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myosarcoma   ex of malignant tumor derived from muscle tissue  
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angiogenesis   process through which a tumor supports its growth by creating its own blood supply  
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antiangiogenesis   form of treatment that disrupts blood supply to the tumor  
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cancer   class of diseases characterized by uncontrolled division of cells & ability to invade other tissues by growth or metastasizing  
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metastasize   to spread from one place to another - from primary to secondary site  
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Most common sites of metastatic tumors   bones, liver, lungs  
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When cancer metastasizes, it often does so through   the circulatory system or lymphatic system  
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metastasis   process by which cancer is spread to new site, also describes tumor itself. transition  
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carcinoma   malignant tumor that occurs in epithelial tissue, tend to infiltrate & produce metastases (new cancer sites)  
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carcinoma in situ   malignant tumor in its original position that has not yet disturbed or invaded surrounding tissue  
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in situ   place where cancer 1st occurred  
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adenocarcinoma   any one of a large group of carcinomas derived from glandular tissues  
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sarcoma   malignant tumor that arises from connective tissues, including hard, soft, & liquid.  
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sarc   flesh  
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hard-tissue sarcomas   arise from bone or cartilage  
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osteosarcoma   hard-tissue sarcoma that involves upper shaft of the long bones, pelvis, or knee  
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soft-tissue sarcomas   cancers of the muscle, fat, fibrous tissue, blood & lymphatic vessels, or other supporting tissue like synovial tissues  
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synovial tissues   line cavities of joints  
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synovial sarcoma   tumor of the tissues surrounding a synovial joint such as knees or elbows  
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liquid-tissue sarcomas   arise from blood & lymph  
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leukemia   cancer of the WBC's in the bone marrow  
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staging   process of classifying tumors by how far the disease has progressed, potential for responding to therapy, & prognosis  
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cancer stages indicated by   letters, #'s, Roman numerals  
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Stage I colorectal cancer   cancerous tumor has formed w/in polyp inside colon but has yet to invade surrounding tissue  
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Stage II colorectal cancer   cancer has invaded the underlying tissue  
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Stage III colorectal cancer   cancer has spread to the underlying tissues & nearby lymph nodes  
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lymphoma   general term applied to malignancies affecting lymphoid tissues: lymph nodes, spleen, liver, bone marrow  
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2 most common types of lymphoma   Hodgkin's lymphoma & non-Hodgkin's lymphoma  
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Hodgkin's Lymphoma   aka Hodgkin's disease, cancer of immune system distinguished by presence of large, cancerous lymphocytes: Reed-Sternberg cells, compromises ability to fight infection  
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Non-Hodgkin's Lymphoma   more common/ all other than Hodgkin's. Originate in lymphocytes, some agressive, others indolent  
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indolent   slow growing  
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aggressive   fast growing  
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breast cancer   carcinoma that develops from cells of breast & can spread to adjacent lymph nodes & other body sites  
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ER-positive   majority of all breast cancers, means they grow in response to the hormone estrogen  
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BRCA1 & BRCA2 genes   BReast CAncer 1 & 2, abnormal genes that carry a higher risk of breast, ovarian, & certain other cancers. Inherited  
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Ductal carcinoma in situ   DCIS, breast cancer @ earliest stage b4 cancer has broken through wall of milk duct, cure rate nearly 100%  
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infiltrating ductal carcinoma   starts in milk duct & invades the fatty breast tissue outside the duct. Most common form of breast cancer  
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inflammatory breast cancer   IBC, rate but aggressive form of breast cancer where cancer cells block lymphatic vessels in skin of breast. Grows rapidly  
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symptoms of inflammatory breast cancer   pain, rapid increase in breast size, redness or rash on breast, swelling of nearby lymph nodes  
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male breast cancer   can occur in the small amt of breast tissue, similar to those in women  
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stages of breast cancer   0, I, II, III, IV  
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Stage 0 breast cancer   cancer cells found only in 1 location, such as ductal carcinoma in situ  
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Stage I breast cancer   cancer cells have moved beyond duct but have not yet reached outside the breast into the lymph nodes  
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Stage II breast cancer   cancer has increased in size, &/or has reached 1-3 axillary (armpit) lymph nodes  
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Stage III breast cancer   cancer spread to cervical lymph nodes &/or tissues surrounding breast, like chest wall or skin/ Inflammatory breast cancer  
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Stage IV breast cancer   cancer has spread to other organs, most commonly brain, lungs, liver, or bones. Invasive or metastatic cancer.  
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breast self-examination   self-care procedure for early detection of breast cancer. Check for new lumps or changes to shape of nipple or skin changes  
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palpation of the breast   test performed by a trained health care provider to check the texture, size, & consistency of breast  
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mammography   radiographic exam of breasts to detect presence of tumors or precancerous cells  
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mamm/o   breast  
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molecular breast imaging   MBI, nuclear med technique using gamma radiation to detect potential tumors in particularly dense tissue  
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ultrasound   often used as follow-up test when abnormality found by mammography  
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breast MRI   uses magnets & radio wave, & insertion of a contrast medium IV, to get detailed info for those already diagnosed or high risk  
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needle breast biopsy   x-ray or MRI guided needle used to remove small samples of tissue from breast for diagnosis/ planning treatment  
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Less painful and disfiguring than surgical biopsy   needle breast biopsy  
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surgical biopsy   removal of small piece of tissue for exam to confirm a diagnosis  
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sentinel node biopsy   biopsy of 1st lymph node to come into contact w/ cancer cells as they leave organ of origination & start spreading into body  
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lymph node dissection   surgical procedure in which all lymph nodes in major group are removed to determine or slow spread of cancer in area  
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lumpectomy   surgical removal of only cancerous tissue w/ surrounding margin of normal tissue. Remainder of tissue not removed  
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mastectomy   surgical removal of the entire breast & nipple, often includes removal of axillary lymph nodes under adjacent arm  
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radical mastectomy   surgical removal of an entire breast & many surrounding tissues  
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modified radical mastectomy   surgical removal of the entire breast & all of the acillary lymph nodes under adjacent arm  
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breast reconstruction   alternative to wearing an external prosthesis  
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immediate breast reconstruction   begins during same surgery as mastectomy when an "expander" is placed to replace the tissue that was removed  
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delayed breast reconstruction   necessary if surgery followed by radiation.  
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most common forms of treatment for all types of cancer   surgery, chemotherapy, radiation therapy  
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Cancer surgery   remove malignancy + some surrounding tissue, 1 or more nearby lymph nodes. Also laser or cryo surgeries  
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Laser surgery for cancer   targeted beams of light to destroy cancer cells  
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Cryosurgery for cancer   cancerous cells frozen & destroyed using a substance such as liquid nitrogen  
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chemotherapy   use of chemical agents & drugs in combinations selected to destroy malignant cells & tissues  
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chemoprevention   use of natural or synthetic substances (drugs/vitamins) to reduce risk of developing cancer or to reduce chance of recurrence  
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antineoplastic   medication that blocks development, growth, or proliferation of malignant cells  
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proliferation   increase rapidly  
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cytotoxic drugs   used for both immunosuppression & chemotherapy  
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radiation therapy   goal of destroying only cancerous tissues while sparing healthy ones  
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brachytherapy   use of radioactive materials in contact w/ or implanted into tissues to be treated  
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teletherapy   radiation therapy administered @ a distance from the body.  
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tomotherapy   combination of tomography w/ radiation therapy to precisely target tumor being treated. Radiation slice by slice to tumor  
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tom/o   slice  
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targeted therapy   a developing form of anticancer drug therapy that uses drugs or other substances to ID & attack specific cancer cells only  
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adjuvant therapy   sometimes used after primary cancer treatments to decrease chance of recurrence.  
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adjuvant   an agent intended to increase the effectiveness of a drug  
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adjuvant therapies   chemotherapy, hormone therapy, radiation, immunotherapy, or targeted therapy  
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clinical trials   testing new & promising cancer treatments not yet approved by FDA  
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A, Ab   antibody  
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AG, Ag   antigen  
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CA, Ca   cancer  
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CIS   carcinoma in situ  
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DCIS   ductal carcinoma in situ  
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HZ   herpes zoster  
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HL   Hodgkin's lymphoma  
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IG   immunoglobulin  
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LE   lymphedma  
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MMR   measles, mumps, and rubella vaccination  
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MET   metastasis  
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met   metastasize  
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NHL   non-Hodgkin's lymphoma  
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VSZ   varicella  
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