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Cells of Inflammation

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Answer
What are endothelial cells?`   Single-cell thick lining of blood vessels; they can produce antiplatelet and antithrombotic agents that help keep the vessel clear and open and they also are responsible for the constriction and dilation of said vessels  
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What are platelets?   1. Small membrane bound disks that circulate in the blood 2. Activated platelets also release strong inflammatory mediators which increases vascular permeability  
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What are leukocytes?   1. Major cellular components during inflammatory response  
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What are the sub-cell types within the category of leukocytes?   1. Granulocytes (neutrophils, eosinophils, basophils ) which contain cytoplasmic granules 2. Agranulocytes (monocytes/macrophages and lymphocytes) which do not have any granules  
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Neutrophils make up what % of circulating WBC's?   60-70%  
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How fast are neutrophils in reacting to tissue damage?   They are the 1st to arrive on scene, usually arriving within 90 minutes  
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How do neutrophils act when at the site of injury?   They act as scavengers, eating other bacteria and cellular debris via phagocytosis  
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How long do neutrophils live in circulation?   They have a short life span, dying by apoptosis (cellular suicide) and disappear between 24-48 hours after entering the damaged site  
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Eosinophils make up what % of circulating WBCs?   2-3%  
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How fast are eosinophils in reacting to tissue damage?   Usually arrive on scene 2-3 hours after neutrophils  
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Eosinophils play an important role in this type of reaction   Allergic reactions because they control the release of specific chemical mediators  
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Why would eosinophils present in chronic inflammation?   Because they have a longer life span that neutrophils do  
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