med-surg
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anemia | a manifestation of a pathologic process characterized by a reduction below normal in the number of erythrocytes, quantity of hemoglobin, and/or the volume of packed red cells (hematocrit) in the blood
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aplastic anemia | a disease in which the patient has peripheral blood pancytopenia (decrease of all blood cells types) and hypocellular bone marrow
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autologous | in transplantation, denotes removal of the patients own tissue and the fiving back of the tissue to that person
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disseminated intravascular coagulation (DIC) | a serious bleeding disorder resulting from abnormally initiated and accelerated clotting
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hemachromatosis | an autosomal recessive disease characterized by increased intestinal iron absorption and, as a result, increased tissue iron depostition
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hemolytic anemia | an anemia caused by destruction of RBC's at a rate that ex ceeds production
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hemophilia | heraditary bleeding disorders caused by defective or deficient clotting factors; classic hemophilia A is a sexlinked recessive genetic disorder caused by deficient factor VIII; hemophilia B is a deficiency of factor IX
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hepatomegaly | an abnormal enlargement of the liver
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induction therapy | the initional, aggressive stage of cancer treatment htat attempts to destroy malignant cells and bring about a remission
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iron-deficiency anemia | anemia caused by inadequate iron for hemoglobin production
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leukapharesis | process by which blood is withdrawn from a vein, white blood cells are selectively removed, and the remaining blood is reinfused into the donor
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leukemia | general term used to describe a group of malignant disorders affecting the blood and blood-forming tissues of the bone marrow, lymph system, and spleen
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lymphadenopathy | enlargement of the lymph nodes or lymph vessels
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lymphoblasts | large immature cells that normally develop into lymphocytes
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lymphocytic leukemia | defect in proliferation and maturation of lymphocytes
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megaloblastic anemias | group of disorders caused by impaired DNA synthesis and characterized by the presence of large red blood cells
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multiple myeloma | condition in which neoplastic plasma cells infiltrate the bone marrow and destroy bone
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myeloblasts | large, immature cells that normally develop into gradulocytes
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myelodysplastic syndrome | a group of related hematologic disorders characterized by a change in the quantity and quality of bone marrow elements
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myelogenous leukema | a defect in proliferation and maturation of granulocytes
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non-Hodgkin's lymphoma | a heterogeneous group of malignant neoplasms involving lymphoid tissue
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pernicious anemia | type of megaloblastic anemia resulting from inadequate gastric secretion of intrinsic factor necessary for absorption of cobalamin (vitamin B12)
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Philadelphia chromosome | translocation of the long arm of chromosome 9 found in the abnormal myeloblasts, erythroblasts, and megakaryoblasts of 90% if oatuebts of patients with chronic myelogenous leukemia
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polycythemia | production and presence of increased numbers of red blood cells
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sickle cell crisis | an exacerbation of sickle cell anemia when sickle cell hemoglobin assumes various crescent or sickle shapes, occluding small blood vessels
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sickle cell disease | group of inherited, autosomal recessive disorders characterized by the presence of an abnormal form of hemoglobin in the erythrocyte
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sickle cell hemoglobin | abnormal hemoglobin that caused development of deformed crescent-shaped red blood cells when oxygen tension is lowered
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sickle cell trait | heterozygous state in which an individual has only one sickle cell gene paired with a normal homoglobin gene
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splenomegaly | abnormal enlargement of the spleen
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thalassemia | an autosomal recessive genetic disorde of inadequate production of normal hemoglobin
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thrombocytopenia | a reduction of the platelet count below the normal range of 150,000 to 400,000/ul
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