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Duke PA Normal Pregnancy

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Question
Answer
In a normal pregnancy the hCG doubles every __   48 hours  
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Beta-hCG is first detectable in maternal blood __ after conception   6-8 days  
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False positive pregnancy tests occur at hCG levels of __mIU/ml   5-25  
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If the fetus is lost before 22 weeks it is classified as a __   Miscarriage  
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If the fetus is lost after 22 weeks of gestation it is classified as a __   Stillbirth  
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What is considered the gestational age of viability   22 weeks  
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During pregnancy hemodilution is normal and produces __   Physiologic Anemia  
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During pregnancy body water increases by __   6.5-8.5L (most significant adaptation in PG)  
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How is the heart affected during pregnancy   Displaced to the left and upward, increase in left ventricular end diastolic dimension, output is increased by 30-50%  
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What are some normal changes in pregnancy that may mimic heart disease   Dyspnea (most common complaint before 20 wks), decreased exercise tolerance/ fatigue/ occasional orthopnea/ chest discomfort, Edema  
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What happens to nasal mucosa during pregnancy   It becomes more edematous and erythematous, hypersecretion of mucus  
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What happens to lung volume during pregnancy   Decreases by 5%, max volume that can be inhaled increased by 5-10%  
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What happens to pulmonary function during pregnancy   Hyperventilation  
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Pregnancy causes a state of chronic respiratory __   Alkalosis  
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The kidneys excrete more __ during pregnancy   Bicarb  
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What changes with WBC’s during pregnancy   Increased by 5,600-12,000  
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Renal plasma flow __ in pregnancy   Increases  
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Because of dilation of the renal pelvis there is an increased incidence of __ in pregnancy   Pyelonephritis  
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What happens to appetite during pregnancy   Increased by about 200 Kcal/day  
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What happens to the stomach during pregnancy   Tone and motility decreases, increased GERD  
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Morning sickness complicates __% of pregnancies   70  
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What is the time frame of morning sickness (onset/improvement)   Onset in 4-8 weeks, improvement by 14-16 weeks  
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What is the treatment of morning sickness   Largely supportive (reassurance, avoid triggers, frequent small meals, acupressure/ginger/V B6  
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What are the skin changes in pregnancy   Hyperpigmentation, linea alba becomes linea nigra, pigmented nevi/freckles/recent scars  
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What are the hair changes in pregnancy   Mild degree of hirsutism  
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Striae (stretch marks) affect up to __% of pregnant women   90%  
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In the fetus what is the vasculature that bypasses the liver   Ductus venosus  
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What is the bypass that allows blood to flow from the right atrium to the left atrium   Foramen ovale  
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What is the bridge that allows blood to pass from pulmonary veins to the aorta   Ductus arteriosus  
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When does the foramen ovale change to the fossa ovalis   When the baby takes its first breath, the pressure from the lungs closes the valve  
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What happens to the ductus venosus and the ductus arteriosus after a child is born   They become ligaments (ligamentum venosum, ligamentum arteriosum)  
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The hypervolemia of pregnancy compensates for maternal blood loss at delivery, which averages __ml for vaginal and __ml for c-section   500-600, 1000  
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With uterine enlargement and diaphragmatic elevation, the heart rotates on its long axis in left upward displacement. As a result the apical beat shifts __   Laterally  
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if hCG results uncertain, repeat test in:   2 days  
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very high hCG levels seen in:   molar PG (gestational trophoblastic disease)  
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Not normal symptoms (re: heart)   syncope, chest pain with exertion, progressive orthopnea, and hemoptysis  
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