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Benign and Malignant Tumors

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Question
Answer
Benign - Mode of Growth   Relatively slow growth by expansion; encapsulated; cells adhere to each other  
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Malignant - Mode of Growth   Rapid growth; invades surrounding tissue by infilteration  
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Benign - Cells under microscopic examination   Resemble tissue of origin; well differentiated; appear normal  
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Malignant - Cells under microscopic examination   Do not resemble tissue of origin; vary in size and shape; abnormal appearance and function  
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Benign - Spread   Remains localized  
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Malignant - Spread   Metastasis; cancer cells carried by blood and lymphatics to one or more other locations; secondary tumors occur  
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Benign - Other properties   No tissue destruction; not prone to hemorrhage; may be smooth and freely movable  
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Malignant - Other properties   Ulceration and/or necrosis; prone to hemorrhage; irregular and less movable  
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Benign - Recurrence   Rare after excision  
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Malignant - Recurrence   A common characteristic  
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Benign - Pathogenesis   Symptoms related to location with obstruction and/or compression of surrounding tissue or organs; usually not life-threatening unless inaccessible  
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Malignant - Pathogenesis   Cachexia; pain; fatal if not controlled  
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