Benign and Malignant Tumors
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Benign - Mode of Growth | Relatively slow growth by expansion; encapsulated; cells adhere to each other
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Malignant - Mode of Growth | Rapid growth; invades surrounding tissue by infilteration
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Benign - Cells under microscopic examination | Resemble tissue of origin; well differentiated; appear normal
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Malignant - Cells under microscopic examination | Do not resemble tissue of origin; vary in size and shape; abnormal appearance and function
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Benign - Spread | Remains localized
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Malignant - Spread | Metastasis; cancer cells carried by blood and lymphatics to one or more other locations; secondary tumors occur
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Benign - Other properties | No tissue destruction; not prone to hemorrhage; may be smooth and freely movable
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Malignant - Other properties | Ulceration and/or necrosis; prone to hemorrhage; irregular and less movable
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Benign - Recurrence | Rare after excision
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Malignant - Recurrence | A common characteristic
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Benign - Pathogenesis | Symptoms related to location with obstruction and/or compression of surrounding tissue or organs; usually not life-threatening unless inaccessible
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Malignant - Pathogenesis | Cachexia; pain; fatal if not controlled
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