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Benign and Malignant Tumors

Benign - Mode of Growth Relatively slow growth by expansion; encapsulated; cells adhere to each other
Malignant - Mode of Growth Rapid growth; invades surrounding tissue by infilteration
Benign - Cells under microscopic examination Resemble tissue of origin; well differentiated; appear normal
Malignant - Cells under microscopic examination Do not resemble tissue of origin; vary in size and shape; abnormal appearance and function
Benign - Spread Remains localized
Malignant - Spread Metastasis; cancer cells carried by blood and lymphatics to one or more other locations; secondary tumors occur
Benign - Other properties No tissue destruction; not prone to hemorrhage; may be smooth and freely movable
Malignant - Other properties Ulceration and/or necrosis; prone to hemorrhage; irregular and less movable
Benign - Recurrence Rare after excision
Malignant - Recurrence A common characteristic
Benign - Pathogenesis Symptoms related to location with obstruction and/or compression of surrounding tissue or organs; usually not life-threatening unless inaccessible
Malignant - Pathogenesis Cachexia; pain; fatal if not controlled
Created by: wallace263