Duke PA Multiple Sclerosis
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| MS is an __ disorder of the CNS that affects physical, cognitive, and psychological function | inflammatory demyelinating
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| median onset of age for MS is __ years | 30
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| MS is more common in __ | women
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| common manifestations of MS | optic neuritis, transverse myelitis, paresthesias, ataxia, weakness or incoordination, spasticity, cognitive impairment
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| the hallmark for the diagnosis of MS | abnormalities of the CNS separated by place and time
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| inflammation leads to demylination which leads to __ | axonal loss
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| MS is an __ disease | episodic
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| at diagnosis 85% of people with MS present with a __ | relapsing form of the disease
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| the pattern of MS over time includes | relapses (attacks, disability (gradual progressive deterioration of function), or a combination of both
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| very few patients with MS have | benign MS, in which there is complete recovery between relapses
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| MS pathophysiology in a nutshell | autoimmune inflammation of the oligodendrocytes, leading to demylination and axonal loss
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| relapse of MS is treated with | corticosteroids
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