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WVSOM -- Neuroanatomy -- Biochemistry of Vision

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Refraction   bending of light at anangled surface  
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What happens to light when it hits a glass surface perpendicular to light rays?   does not bend  
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What does a convex lens do?   causes light rays to converge to a focal point  
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What will a concave lens do?   cause light rays to diverge  
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What does visible light range from?   400nm – 700 nm  
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Rods   sensitive to light so good for dim light or night vision. Do not respond well to moving stimuli. Slow response time  
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Cones   not sensitive to dim light and respond quickly. Daytime vision and color  
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How many cones per eye?   5 million  
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What are the 3 classes of cones?   Blue, green and red  
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What are blue cones for?   short wavelength  
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What are green cones for?   medium wavelengths  
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What are red cones for?   long wavelengths  
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What is photo pigment for?   responsible for absorbing the energy from the light into a cascade of events  
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Where aer the photo receptors at?   outer segments of the membranes  
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What does photopigment consist of?   retinal and opsin  
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What is retinal?   vit A derivative  
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What is opsin?   glycoprotein  
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How many opsins are there?   4 – 1 for rods (scotopsin and then 3 in cones (red, green , blue)  
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What photopigment do rods have?   rhodopsin  
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What are photoreceptors in the dark?   at rest and somewhat depolarized  
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What happens to photoreceptors int eh presence of light?   hyperpolarizes  
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How do the photoreceptors stay depolarized?   Na+ channels open  
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How are Na+ channels in the dark?   open  
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How are Na+ chennels in the light?   closed  
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What gates are on Na+ channels?   cGMP  
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What reduces G-protein concentration?   transducin  
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How does transducin lower g-protein concentration?   by activating a phosphodiesterase which reduces cGMP  
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What is the phototranduction pathway?   light activates photopigment, activates tranducin, activates phosphodiesterase, reduces cGMP concentration, Na + chennels close and hyperpolarization occurs, glutamate release is reduced  
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What does phototransduction pathway cause?   amplification  
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What inhibits bipolar cells?   glutamate  
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