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Neuro4
WVSOM -- Neuroanatomy -- Biochemistry of Vision
Question | Answer |
---|---|
Refraction | bending of light at anangled surface |
What happens to light when it hits a glass surface perpendicular to light rays? | does not bend |
What does a convex lens do? | causes light rays to converge to a focal point |
What will a concave lens do? | cause light rays to diverge |
What does visible light range from? | 400nm – 700 nm |
Rods | sensitive to light so good for dim light or night vision. Do not respond well to moving stimuli. Slow response time |
Cones | not sensitive to dim light and respond quickly. Daytime vision and color |
How many cones per eye? | 5 million |
What are the 3 classes of cones? | Blue, green and red |
What are blue cones for? | short wavelength |
What are green cones for? | medium wavelengths |
What are red cones for? | long wavelengths |
What is photo pigment for? | responsible for absorbing the energy from the light into a cascade of events |
Where aer the photo receptors at? | outer segments of the membranes |
What does photopigment consist of? | retinal and opsin |
What is retinal? | vit A derivative |
What is opsin? | glycoprotein |
How many opsins are there? | 4 – 1 for rods (scotopsin and then 3 in cones (red, green , blue) |
What photopigment do rods have? | rhodopsin |
What are photoreceptors in the dark? | at rest and somewhat depolarized |
What happens to photoreceptors int eh presence of light? | hyperpolarizes |
How do the photoreceptors stay depolarized? | Na+ channels open |
How are Na+ channels in the dark? | open |
How are Na+ chennels in the light? | closed |
What gates are on Na+ channels? | cGMP |
What reduces G-protein concentration? | transducin |
How does transducin lower g-protein concentration? | by activating a phosphodiesterase which reduces cGMP |
What is the phototranduction pathway? | light activates photopigment, activates tranducin, activates phosphodiesterase, reduces cGMP concentration, Na + chennels close and hyperpolarization occurs, glutamate release is reduced |
What does phototransduction pathway cause? | amplification |
What inhibits bipolar cells? | glutamate |