Gene Regulation
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| Introns are only found in | Eukaryotic genes
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| DNA --> RNA --> Protein | Central dogma of biology
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| Responsible for deacetylating histones | Histone Deacetylase (HDAC)
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| Responsible for acetylating histones | Histone acetyltransferase (HAT)
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| Control gene expression by regulating or inhibiting gene transcription | Trancription factors
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| Achieved through regulating the enzymatic activity of HDAC and HAT | Regulation of chromatin structure
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| Composed of capping, splicing, polyadenylation, and RNA editing | RNA processing
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| What are the four elements found within an intron | 5' 3' splice site, branch point, polypyrimidine tract
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| Can splicing be regulated | Yes
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| Splicing regulated through the activity of | SR proteins and hnRNP proteins
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| Alternative splicing is a way to increase protein diversity | True
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| When iron levels are low ferritin mRNA is less stable | True
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| When Iron levels are high ferritin mRNA is more stable | True
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| When iron levels are low TfR (transferrin receptor) mRNA is less stable | False
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| When iron leves are high TfR (transferrin receptor) mRNA is less stable | True
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| Nonsense mediated decay is a pathway for regulating RNA degradation | True
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| A paternal deletion of chromosome 15 q11-q13 | Prader-Willi Syndrome
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| A maternal deletion of chromosome 15 q11-q13 | Angleman syndrome
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| DNA methylation commonly occurs in ... regions of the promoter | GC rich
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| DNA methylation is a method of turning off gene expression | True
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Created by:
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