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WVSOM
Gene Regulation
| Question | Answer |
|---|---|
| Introns are only found in | Eukaryotic genes |
| DNA --> RNA --> Protein | Central dogma of biology |
| Responsible for deacetylating histones | Histone Deacetylase (HDAC) |
| Responsible for acetylating histones | Histone acetyltransferase (HAT) |
| Control gene expression by regulating or inhibiting gene transcription | Trancription factors |
| Achieved through regulating the enzymatic activity of HDAC and HAT | Regulation of chromatin structure |
| Composed of capping, splicing, polyadenylation, and RNA editing | RNA processing |
| What are the four elements found within an intron | 5' 3' splice site, branch point, polypyrimidine tract |
| Can splicing be regulated | Yes |
| Splicing regulated through the activity of | SR proteins and hnRNP proteins |
| Alternative splicing is a way to increase protein diversity | True |
| When iron levels are low ferritin mRNA is less stable | True |
| When Iron levels are high ferritin mRNA is more stable | True |
| When iron levels are low TfR (transferrin receptor) mRNA is less stable | False |
| When iron leves are high TfR (transferrin receptor) mRNA is less stable | True |
| Nonsense mediated decay is a pathway for regulating RNA degradation | True |
| A paternal deletion of chromosome 15 q11-q13 | Prader-Willi Syndrome |
| A maternal deletion of chromosome 15 q11-q13 | Angleman syndrome |
| DNA methylation commonly occurs in ... regions of the promoter | GC rich |
| DNA methylation is a method of turning off gene expression | True |