Microbiology Exam 5 Chapters 19-27 Must Know Test Questions
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| Models of action in antimicrobial drugs | -Inhibition of cell wall synthesis
- inhibition of protein synthesis
- inhibition of nucleic replication and transcription
- injury to plasma membrane
-inhibition of synthesis of essential metabolites
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| Drugs which cause inhibition of cell wall synthesis | -Penicillins
-Cephalosporins
-Vancomycin
-Bacitracin
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| Drugs which cause inhibition of protein synthesis | -Chloramphenicol
-Erythromycin
-Tetracyclines
-Streptomycin
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| Which drugs cause inhibition of nucleic acid replication & transcription | -Quinolones
-Rifampin
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| Which drugs cause injury to the plasma membrane | -Polymycin B
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| Medications causing inhibition of synthesis of essential metabolites | -Sulfanilamide
-Trimethoprim
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| Kills microbes directly | Bactericidal
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| Prevents microbes from growing | Bacteriostatic
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| How do we test for microbial susceptibility to chemotherapeutic agents. | Disk-Diffusion method- use ampicillin
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| The mechanisms of drug resistance | 1) blocking entry
2) inactivating enzymes
3) alteration of target molecule
4) efflux of antibiotic
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| What are the common methods of misuse in antibotics? | -Using outdated or weakened antibiotics
-Using antibiotics for the common cold and other inappropriate conditions
-Using antibiotics in animal feed
-Failing complete the prescribed regimen
-Using someone else's leftover prescription
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