Ch. 44: adrenergic and cholinergic receptors
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| what are the two types of cholinergic receptors? | nicotinic and muscarinic
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| ligand gated ion channels in the SNS and PNS | nicotinic
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| nicotinic receptors in the SNS and PNS ganglia are.. | .type I sites
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| nicotinic receptors in the skeletal muscles are... | type II sites
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| M1 receptors found in.. | ANS ganglia, brain, gastric, parietal, vascular smooth muscle
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| M2 receptors found at.. | heart
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| M3 receptors found at.. | glands and bronchial smooth msucle
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| M4 and M5 receptors found at... | CNS
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| these receptors stimulate phospholipase C, which produces IP3 and DAG, which then results in increased intracelluilar calcium | M1,M3, M5
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| these receptors inhibit adenylate cyclase, resultin gin decreased cAMP. this causes potassium efflux and sodium influx. | M2, M4
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| what are the adrenergic receptors? | alpha, beta
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| adreneergic receptor that stimulates adenylate cyclase, yielding cAMP | beta
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| adrenergic receptor stimulating PLC,yielding high DAG, IP3, this resultsin activatd protein kinase C and high calcium | alpha 1
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| inhibits adenylate cyclase, yielding low cAMP | alpha 2
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