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Ch. 44: adrenergic and cholinergic receptors
Question | Answer |
---|---|
what are the two types of cholinergic receptors? | nicotinic and muscarinic |
ligand gated ion channels in the SNS and PNS | nicotinic |
nicotinic receptors in the SNS and PNS ganglia are.. | .type I sites |
nicotinic receptors in the skeletal muscles are... | type II sites |
M1 receptors found in.. | ANS ganglia, brain, gastric, parietal, vascular smooth muscle |
M2 receptors found at.. | heart |
M3 receptors found at.. | glands and bronchial smooth msucle |
M4 and M5 receptors found at... | CNS |
these receptors stimulate phospholipase C, which produces IP3 and DAG, which then results in increased intracelluilar calcium | M1,M3, M5 |
these receptors inhibit adenylate cyclase, resultin gin decreased cAMP. this causes potassium efflux and sodium influx. | M2, M4 |
what are the adrenergic receptors? | alpha, beta |
adreneergic receptor that stimulates adenylate cyclase, yielding cAMP | beta |
adrenergic receptor stimulating PLC,yielding high DAG, IP3, this resultsin activatd protein kinase C and high calcium | alpha 1 |
inhibits adenylate cyclase, yielding low cAMP | alpha 2 |