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GI Review 2 (CM)

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
A screening colonoscopy in a patient 50 years or older with an average risk of colorectal cancer should be done:   every 10 years*  
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To diagnose acute pancreatitis order   Serum amylase & Lipase*  
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2-4 wk old infant with intermittent, non-bilious projectile vomiting most likely has?   pyloric stenosis*  
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This is the most frequent cause of intestinal obstruction in 3-12 month old?   intussusception*  
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Always think of Projective Vomiting in young infant   pyloric stenosis  
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Diagnosis of pyloric stenosis is by   UGI series or ultrasound  
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Treatment of pyloric stenosis involves   pyloromyotomy  
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Intestine telescopes in on itself   Intussusception*  
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Bloody bowel movement seen during Intussusception is called   Currant Jelly Stools*  
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This mass is pathognomonic for intussusception   Sausage shaped mass*  
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Hirschsprung Disease is   failure to pass meconium that results in functional obstruction and massive dilation of colon  
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Pathophysiology of intussusception   Invagination of portion of intestine into itself  
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Treatment for Wilm's tumor   surgery  
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Diagnosis for Intussusception is via   Barium enema (is diagnostic and therapeutic)  
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Lanugo   fine hair on the face  
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People on corn (maize) diets   Niacin deficiency (pellagra)*  
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Niacin deficiency AKA   Pellagra*  
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3 D's of pellagra   Diarrhea, dermatitis, dementia*  
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Folate deficiency causes this type of anemia   macrocytic anemia  
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This nutrient plays a key role in nucleic acid synthesis   Folate*  
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Early manifestations of this deficiency include occlusive vascular disease and thrombosis   Folate deficiency  
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Vitamin B1 deficiency AKA   Thiamine deficiency  
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Causes beri beri, mostly in malnourished and alcoholics   Thiamine deficiency (B1)*  
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Thiamine deficiency (B1) manifests with   acute heart failure, neurologic deficits, and epilepsy*  
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Cobalamin deficiency AKA   Vitamin B 12 deficiency*  
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Cobalamin deficiency manifests as this anemia   macrocytic anemia  
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Cobalamin deficiency (Vit B 12) manifests with   peripherial neuropathy, parasthesias & demyelination of the corticospinal tract  
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Vitamin B6 deficiency AKA   Pyridoxine deficiency*  
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Pyridoxine (B6) deficiency presents with   peripheral neuropathy, seborrheic dermatitis, glossitis and cheilosis*  
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Deficiency that causes hemolytic anemia in premature infants   Vitamin E deficiency  
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Define Cullen's sign   Ecchymosis around the umbilicus*  
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Define Grey Turner's sign   Ecchymosis around the flanks*  
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Lisker's sign   Tibial bone tenderness that can sometimes be illicited with DVT*  
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Kehr's sign   Pain in the left shoulder secondary to splenic rupture  
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Abdominal rebound tenderness that indicates peritoneal irritation is what sign   Blumberg's sign  
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This marker is present during the window period of Hep B   HBcAg*  
🗑
The first serological marker to appear in Hep B infection   HBsAg*  
🗑
HBeAg is a marker for   Infectivity with Hep B*  
🗑
Is the hepatitis B core antigen   HBcAG*  
🗑
Is seen at the end of an infection with Hep B and gives immunity   Anti-HBs*  
🗑
History of portal hypertension/ liver disease think   Esophageal varices*  
🗑
Dx & Tx of esophageal varices   Endoscopy  
🗑
Pyrosis is   Heartburn  
🗑
Dysphagia of solids and liquids   Achalasia*  
🗑
'birds beak' occurs in   Achalasia*  
🗑
Dx of achalasia is made via   Esophageal manometry*  
🗑
Transient cystic duct obstruction   Biliary colic*  
🗑
Female, fertile, forty, fat   Cholelithiasis*  
🗑
Common bile duct stone   Choledocholithiasis*  
🗑
Sustained obstruction of cystic duct   Acute cholecystitis*  
🗑
Skip lesions are found in   Crohn's disease*  
🗑
'string sign' occurs in   Crohn's disease*  
🗑
Cobblestoning is seen in   Crohn's disease  
🗑
Treatment of Crohn's disease   Sulfasalazine*  
🗑
Dx and Tx of mesenteric ischemia via   Angiography  
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Second most common cancer death in men and women   Colon cancer  
🗑
Apple core lesion on barium enema indicates   Colon cancer*  
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Beri beri is seen in this vitamin deficiency   Thiamine deficiency*  
🗑
Most common complication of portal hypertension   esophageal varices  
🗑
Corkscrew on Barium swallow   Esophageal spasm*  
🗑
Esophageal Cancer associated with smoking   Squamous cell carcinoma*  
🗑
Esophageal Cancer associated with alcohol   Squamous cell carcinoma*  
🗑
Esophageal Cancer associated with Barrett's   Adenocarcinoma*  
🗑
Diagnosis of GERD is by   Barium swallow  
🗑
Diagnosis of peptic ulcer disease (PUD) is by   Upper endoscopy  
🗑
Gastric adenocarcinoma has a strong connection with   H. pylori and smoking  
🗑
First sign of intestinal obstruction is   Hyperactive bowel sounds  
🗑
Diagnosis of celiac disease   Mucosal biopsy*  
🗑
Most common abdominal cancer in children   neuroblastoma*  
🗑
Most common cause of upper GI bleed   PUD*  
🗑
Double bubble sign   Duodenal atresia  
🗑
Hirschsprung's disease AKA   Congenital megacolon*  
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This is caused by the congenital abscense of Meissners and Auerbach's autonomic plexuses enervating the bowel wall   Hirschsprung disease  
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A congenital aganglionosis of the colon   Hirschsprung disease  
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Treatment for ascities   Salt restriction & bed rest*  
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Common complication seen in crohn's disease   Fistulas*  
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MCC of gastroenteritis in children   Rotavirus*  
🗑
MCC of constipation in kids   Functional (voluntary withholding or diet)*  
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Epigastric mass in a child 2-4 weeks old, is most suggestive of   Pyloric stenosis*  
🗑
Pernicious anemia is associated with what cancer   Gastric cancer*  
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Cancers of skin, esophagus or mouth are usually   Squamous cell carcinomas  
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Pain worse after eating, think   Gastric PUD  
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Pain relieved with food or antacids   Duodenal PUD  
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Zollinger-Ellison syndrome is a   Gastrinoma*  
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Liver drains into the   Hepatic duct  
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Gall bladder drains into the   Cystic duct  
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Pancreas drains into the   pancreatic duct  
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Common bile duct drains into the   duodenum  
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The hepatic duct, cystic duct, & pancreatic duct all drain into the   Common bile duct  
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Two causes of unconjugated bilirubinemia   Hemolysis & Gilberts syndrome  
🗑
Murphy's sign is seen in   Acute cholecystitis*  
🗑
Primary sclerosing cholangitis presents with   Fatigue, jaundice, puritis, pain*  
🗑
Primary sclerosing cholangitis is   Chronic inflammation & fibrosis of the bile ducts  
🗑
Fe overload is associated with   Hemochromatosis*  
🗑
Cu overload is associated with   Wilson's disease*  
🗑
Major risk factor for hepatocellular carcinoma   Hepatitis B*  
🗑
Hepatitis seen in India, SE and central Asia   Hep E  
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Crohn's disease typically involves the   Terminal ileum & cecum*  
🗑
Air/ fluid levels on abdominal upright KUB   Small bowel obstruction  
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LLQ Pain & mass, fever, leukocytosis indicates   Diverticulitis*  
🗑
Diagnosis of diverticulitis is   Clinical based  
🗑
UC always involves the   Rectum*  
🗑
With Celiac spruce, the patient can eat   CRAP: Corn, Rice, Aeroroot, Potato*  
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Deficiency of vitamin D leads to   Osteomalacia  
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A gastric hormone that activates duodenal/ jejunal receptors to initiate peristalis   motilin  
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What acid base disorder is seen with mesenteric Ischemia   Metabolic acidosis  
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Abdominal pulsatile mass   Abdominal aortic dissection  
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Colicky periumbilical pain that becomes constant in RLQ   Appendicitis*  
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Disease with RUQ pain that radiates to scapula tip   Cholecystitis*  
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+ Kehr's sign   Splenic rupture*  
🗑
Left shoulder pain secondary to subdiaphragmatic irritation is due to   splenic rupture*  
🗑
+ Lloyd's sign   Pyelonephritis*  
🗑
Signs in pancreatitis   Turner's & Cullen's signs*  
🗑
current recommendation for colon cancer screening   FOBT yearly, sigmoidoscopy every 5 years & colonoscopy every 10 years  
🗑
Inability to hold feces in the rectum   Fecal incontinence  
🗑
The reflux of food and stomach acid back into the mouth, brine-like taste   Regurgitation  
🗑
Absence of bowel activity (and bowel sounds) due to a direct insult to the gut   Paralytic ileus  
🗑
Serous fluid accumulation in the abdominal cavity, from cardiac or liver disease   Ascites  
🗑
Define Murphy's sign   Pain over the gallbladder as you press as the patient inspires*  
🗑
(+) Murphy's sign   cholecystitis*  
🗑
Point tenderness over McBurney's Point indicates   Appendicitis*  
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Define Psoas sign   Pain as patient raises right leg against resistance  
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Define obturator sign   Pain as you flex patient right hip and internally rotate  
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Define Rovsing sign   Right side pain with left side pressure  
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Inflammatory bowel disease that increases risk for colon cancer   Ulcerative colitis*  
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Tenesmus   Feeling of incomplete evacuation of the rectum  
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Raised tender red purplish nodules seen in IBD   Erythema nodosum  
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Tenesmus is suggestive of   Proctititis  
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95% of colon cancers are   Adenocarcinomas*  
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Colon cancer metastasizes to the   Liver and then the lung  
🗑
Rectal cancer metastasizes to the   Liver or lung  
🗑
Most common type of Abdominal pain, is   general and/or undiagnosed abdominal pain  
🗑
Cholelithiasis (ultrasound or CT)   ultrasound  
🗑
treat diarrhea with   fluoroquinolone  
🗑
High-sensitivity fecal occult blood test (FOBT), which checks for hidden blood in three consecutive stool samples, should be done   every year (no meat for 5 days)  
🗑
indicates active or ongoing infection Hep B infection   Hepatitis b surface antigen (HBsAg)  
🗑
Most sensitive test for diagnosis of iron deficiency anemia?   A low serum ferritin  
🗑
Antibiotics can cause   C.diff colitis  
🗑
Most common complaint of abused children   Abdominal pain  
🗑
WBCs seldomly over 15,000   Appendicitis  
🗑
Pyloric Stenosis can develop in   neonates  
🗑
Reynold's pentad indicates   Cholangitis*  
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Reynold's pentad includes   Pain, fever, jaundice, hypotension, & mental confusion  
🗑
Charcot's triad includes   RUQ Pain, fever (>40), jaundice  
🗑
Classic history of painless jaundice is seen in   Pancreatic cancer*  
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Define cholangiocarcinoma   Cancer of bile duct wall  
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'Beads on a String' is seen in   Primary sclerosing cholangitis (PSC)  
🗑
Diverticulosis most commonly affects the   Sigmoid colon*  
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Define acute diarrhea   Less than 6 weeks in duration, mostly due to viral infections  
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Define chronic diarrhea   More than 6 weeks in duration  
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Bulky, frothy, oily stools think   Fat malabsorption  
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Difficulty swallowing   Dysphagia  
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Painful swallowing   Odynophagia  
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Split, tear or erosion in epithelium of anal canal usually due to large or hard to pass stools   Anal fissures*  
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Anal fissure are usually located   Posteriorly*  
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Parietal cell secretes   HCL  
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Sister Mary Joseph nodes are seen in   Gastric cancers*  
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Two most common causes of PUD   H. pylori & NSAIDs  
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Define anal fistula   Abnormal opening between anal canal & perianal skin  
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Painless bleeding after defecation   Internal hemorrhoids  
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Triad of malabsorption disease   Chronic diarrhea, weight loss & nutritional deficiency  
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Gold standard test for malabsorption   Quantitative stool fat test  
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Inflammatory response of small bowel to ingestion of gluten proteins found in wheat, rye, & barley   Celiac disease  
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Cutaneous variant of celiac disease   Dermatitis herpetiformis*  
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Intensely pruritic papulovesicular rash of trunk, scalp, & extremities seen in celiac disease   Dermatitis herpetiformis  
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Most common malignancy associated with celiac disease   Lymphoma  
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Inflammatory disease of small bowel secondary to overgrowth of coliforms   Tropical spruce  
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Hyperparathyroidism can cause this GI issue   Acute pancreatitis  
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Peutz-Jeghers syndrome   Melanin spots on the lips, buccal mucosa & tongue and bleeding polypoid lesions in the small intestines  
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Rendu-Osler-Weber   Telangestagias on the face and buccal mucosa and similar lesions in the GI tract  
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Blue - Rubber-Bleb-Nevus   Cavernous hemangiomas of the skin and similar lesions in the small intestines  
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Neurofibromatosis   Café au late pigmentation with peduncalated fibromas and bibromas in the GI tract that may bleed are associated with  
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More than 50% of cases of pill induced esophagitis results from   Tetracycline  
🗑
Describe Markle sign or jar sign   Have patient stand on toes and then drop quickly to heels to find location of abdominal pain  
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Another name for rebound tenderness   Blumberg sign  
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Cullen's sign is associated with   Retroperitoneal bleeding & pancreatitis  
🗑
Pregnancy is associated with improvement in   migranes and PUD  
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Microcytic anemia in a patient that is over 50 year old, think   Colon cancer  
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40 % of advanced neoplasms in colon are located   Proximal to the splenic flexture  
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Colonoscopy for IBD patients is done   Yearly, 8 years after diagnosis  
🗑
Alcoholic fatty liver presents with   RUQ pain, tender hepatomegaly and elevated transaminase levels  
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Inflammatory polyps are associated with which IBD   Ulcerative colitis  
🗑
Define esophageal varices   Dilated submucosal veins in lower esophagus  
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Hematemesis with severe retrosternal 'tearing' pain   Boerhaave's syndrome  
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Complains of dysphagia/ odynophagia; get an   Endoscope (EGD)  
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Nonpropulsive hyperperistalysis of esophagus   Diffuse esophageal spasm (DES)  
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Schatzki rings   Smooth, circumferential structures in the distal esophagus  
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Esophageal web may result from   Iron deficiency anemia  
🗑
White male with long standing GERD   Barrett's esophagus  
🗑
Treat Barrett's with   Long term PPIs / ablation  
🗑
Best test & most cost effective for H. pylori diagnosis   Stool antigen*  
🗑
H. pylori treatment   Amoxicillin, clarithromycin & a PPI*  
🗑
H. pylori treatment for PCN allergic patient   Metronidazole, clarithromycin & a PPI*  
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Zollinger Ellison syndrome is seen with   Recurrent PUD, PUD with hypercalcemia and a serum gastrin level above 150  
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Most common cancer world wide   Gastric cancer*  
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Peptic ulcer disease where patients lose weight   Gastric ulcer disease  
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Peptic ulcer disease where patients gain weight   Duodenal ulcer disease  
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Jaundice occurs at a total bili of   Above 3  
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labs in Gilbert's disease show   Increased total bili, increased indirect, decreased direct  
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Primary sclerosing cholangitis is often associated with   UC (IBD)*  
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Most common etiologies of acute pancreatitis   Gallstones & ETOH abuse  
🗑
Helpful tumor marker for pancreatic cancer   CA 19-9*  
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Painless jaundice   Pancreatic cancer*  
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Treatment for hemochromatosis   Weekly phlebotomy  
🗑
Kay-Fleischer ring on eye exam   Wilson's disease  
🗑
Treat Wilson's disease with   Penicillamine  
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ALT >> AST (20 times elevated)   Viral hepatitis  
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Most common indicator for liver transplant   Hep C*  
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Most common blood borne infection   Hep C*  
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Leading cause of chronic liver failure   Hep C*  
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Most common metastatic cancer   Hepatocellular neoplasm*  
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Tumor marker for Hepatocellular neoplasm   AFP*  
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Patients with celiac spruce cannot eat   NO BROW: Barley, rye, oats wheat  
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MCC of lower GI painless bleeding in patients above 50   Diverticular hemorrhage*  
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Most common area for diverticulosis   Sigmoid colon*  
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Second most common cause of cancer death   Colon cancer*  
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Indirect inguinal hernia   Goes through the internal inguinal ring  
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Direct inguinal hernia   Through the back wall of the inguinal canal  
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Femoral hernia   Protrusion through the femoral ring  
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Hiatal hernia   Stomach/ intestines protrudes into chest cavity through diaphragm defect  
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Hemochromatosis trait is   Autosomal recessive  
🗑
Hemophilia A & B trait is   X linked recessive  
🗑
Child swallowed Drano, what to do   Lavage (anything toxic)*  
🗑
Cell change in Barrett's esophagus is from   Squamous to columnar epithelium  
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Outpouching of the upper esophagus   Zenker's diverticulum  
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Rosary bead appearance in esophagus   Diffuse esophageal spasm  
🗑
Tumor marker for pancreas   CA 19-9*  
🗑
Tumor marker for liver   AFP*  
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Tumor marker for colon   CEA*  
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Tumor marker for ovarian   CA 125*  
🗑
Tumor marker for prostate   PSA*  
🗑
Which types of hepatitis are acute   Hepatitis A & E  
🗑
Which types of hepatitis can become chronic   Hepatitis B, C & D  
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Which types of hepatitis are transmitted via the fecal oral route   Hepatitis A & E  
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Which types of hepatitis are transmitted by blood & body fluids   Hepatitis B, C & D  
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Tumor marker for seminoma testicular cancer   HCG*  
🗑
Tumor marker for non-seminoma testicular cancer   AFP*  
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Best test to evaluate the livers synthetic functions   Prothrombin time & INR  
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Diabetes in a young person with a GI complaint   gastroparesis  
🗑
common causes of food-borne toxin-induced diarrhea   Staphylococcus aureus, clostridium perfringens, and bacillus cereus  
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Daycare associated diarrheal illness   rotavirus  
🗑
vitamin B2 aka   riboflavin  
🗑
Cardiomegaly and congestive heart failure with a high cardiac output is associated with a deficiency of   thiamin (vitamin B1)  
🗑
H2-Receptor Antagonists (H2RAs) include   Cimetidine, ranitidine, Famotidine & nizatidine  
🗑
MOA of H2-Receptor Antagonists (H2RAs)   Inhibit gastric secreation by blocking histamine (H2) receptors on parietal cell  
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uses of H2-Receptor Antagonists (H2RAs)   Dyspesis, GERD, PUD  
🗑
ADRs of Cimetidine   drug fever, ED & gynecomastia  
🗑
Proton Pump Inhibitors (PPIs) include   Omeprazole, lansoprazole  
🗑
MOA of Proton Pump Inhibitors (PPIs)   Inhibits parietal cell H/K ATP pump  
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PPIs should be administered   30 to 60 minutes before first meal  
🗑
uses of Proton Pump Inhibitors (PPIs)   GERD, PUD, Zollinger Ellison syndrome, H. pylori  
🗑
ADRs of Proton Pump Inhibitors (PPIs)   iron deficient & pernicious anemia, fractures  
🗑
Four neurotransmitter sites important in the vomiting reflex   Inner ear (M1: Muscarinic; H1: Histamine) & Systemic (D2: dopamine, 5-hydroxytryptamine 3: serotonin)  
🗑
uses of Dimenhydrinate (dramamine)   motion sickness  
🗑
All febrile patients admitted with ascites must have this performed   Abdominal paracentesis  
🗑
Diagnosis of Mallory Weiss tear with   Esophagogastroduodenoscopy (EGD)  
🗑
Esophageal varices presents with   Hematemesis, melena & hematochezia  
🗑
Treat esophageal varices with   EGD, variceal banding; Sclerotherapy  
🗑
Long term treatment of esophageal varices   Beta blockers, No ETOH  
🗑
Boerhaave's syndrome is secondary to   Instrumentation (EGD)  
🗑
Pill induced esophagitis caused by   NSAIDs, KCl, Alendronate (Bisphosphonate) Doxy (tetracyclines)  
🗑
Treat Achalasia with   Botox injections at LES, myotomy  
🗑
Diagnosis Zenker's Diverticulum with   Barium esophagram  
🗑
Esophageal web causes connective tissue effect called   Plummer Vinson syndrome  
🗑
Treat esophageal web by   Treating iron deficiency anemia  
🗑
Diagnosis for esophageal cancer   Endoscopy with biopsy  
🗑
50% of patients with GERD develop   Reflux esophagitis  
🗑
GERD presents with   Heartburn, regurgitation, nausea, throat irritation & cough  
🗑
Heartburn exacerbated by meals, bending over, recumbency, relaxes LES & weight gain   GERD  
🗑
Workup for GERD   4 weeks on PPIs, test for H pylori  
🗑
Complicated disease or alarm symptoms with GERD   GI bleeding, anemia, dysphagia, odynophagia, wt. loss, NSAID use, ulcer disease  
🗑
In unresolved GERD do   Endoscopy, pH monitoring, fundoplication  
🗑
Screening in Barrett's   Endoscopy every 3 - 5 years  
🗑
EGD shows orange/ salmon colored changes to mucosa   Barrett's esophagus  
🗑
Most common PUD   Duodenal  
🗑
Age for duodenal peptic ulcer disease   30 - 55 y/o  
🗑
Age for gastric ulcer diseased   50 - 70 y/o  
🗑
PUD is more common in   NSAID and H. pylori infection  
🗑
Risk factors for NSAID Gastropathy   Age, Hx PUD/ bleed, NSAID overuse, concomitant corticosteroid tx  
🗑
Red flags to get and EGD   Anemia, weight loss, + hemoccult stools, hematemesis, melena, persistent vomiting, dysphagia  
🗑
Treatment for PUD if under 50 and no red flags   PPI for 4 weeks, check H. pylori  
🗑
Gold standard diagnosis for PUD   Endoscopy (EGD)  
🗑
Do not have to rescope this ulcer   Duodenal ulcer  
🗑
Treatment for gastric ulcer   PPI bid for 1 month; PPI qd for 1 month; and rescope after 6 -8 weeks  
🗑
Complications of PUD   Perforation, gastric outlet obstruction, bleeding  
🗑
Normal level of total bilirubin   0.2 - 1.2  
🗑
Elevated bilirubin levels are due to   Abnormal formation, transport, metabolism & excretion  
🗑
Bilirubin levels in Choledocholithiasis   Increased total bili, increased direct, decreased indirect  
🗑
Most common stones in Cholelithiasis   Cholesterol  
🗑
Common symptom of biliary colic   Nocturnal pain  
🗑
Acute cholecystitis presents with   Intense persistent pain, n/v, fever, murphy's sign  
🗑
Acute cholecystitis labs show   Leukocytosis with a left shift  
🗑
Female with generalized fatigue, jaundice & puritis   Primary biliary cirrhosis  
🗑
Diagnosis of primary biliary cirrhosis by   Liver biopsy, + AMA (anti-mitochondrial antibody)  
🗑
Treatment of primary biliary cirrhosis   Bile acid sequestrates (URSOdiol), transplant  
🗑
Diagnosis of autoimmune hepatitis   Increased AST/ALT, + ANA (anti-nuclear antibody), + ASMA (anti-smooth muscle antibody)  
🗑
Treatment of autoimmune hepatitis   Prednisone/ immunomodulators (azathioprine)  
🗑
PSC leads to   End stage liver failure  
🗑
Nontender palpable gallbladder with history of weight loss   Cholangiocarcinoma  
🗑
Klatskin tumor most commonly occurs at   Junction of right & left main hepatic ducts  
🗑
Cancer associated with primary sclerosing cholangitis   Cholangiocarcinoma  
🗑
Meds that cause acute pancreatitis   Azathioprine, pentamide, valproate, thiazides  
🗑
Acute pancreatitis presents with   Sever epigastric pain, n/v, tachycardia, orthostasis, dehydration, hypotension  
🗑
Diagnosis of acute pancreatitis   Increased serum amylase & lipase, leukocytosis with left shift, CT  
🗑
ICU admission of acute pancreatitis if   AMS, hypoxemia, HCT >50, oliguria, tachycardia with hypotension  
🗑
Ranson's criteria is for   Necrotizing pancreatitis  
🗑
Ranson's criteria includes   Age > 55, WBC > 16,000, BS > 200, LDH > 350, AST >250 & low serum calcium  
🗑
Most common area of pancreatic cancer   Head of pancreas  
🗑
Diagnosis of pancreatic cancer with   CT & CA 19-9  
🗑
Pancreatic cancer presents with   Vague epigastric pain straight through to the back, painless jaundice, weight loss, anorexia  
🗑
Hep A infection possible if patient has   Foreign travel, flooded area of US, or poor sanitation  
🗑
Vaccinated patient to Hep B will show positive to   Anti HBsAg only  
🗑
Immunity (recovered) patient to Hep B shows   + Anti HBsAg; + Anti HBcAg; (+/-) Anti-HBe  
🗑
Chronic active Hep B shows   (+) HBsAg; (+) Anti HBsAg; (+) Anti-HBe  
🗑
Chronic active infections of Hep B   (+) HBsAg, (+) Anti-HBcAg,(+) HBeAg  
🗑
Always done to confirm Hep C   liver biopsy  
🗑
Treatment for Hep C   Pegylated interferon with ribavirin  
🗑
MCC of cirrhosis   Alcoholic hepatitis  
🗑
Confirm non-alcoholic fatty liver (NASH) with   Liver biopsy  
🗑
Hepatocellular neoplasm mets to   Lung, colon, breast & prostate  
🗑
Manage Crohn's or UC with   Aminosalicylates/ 5ASA (mesalamine) to Immunomodulators (azathioprine) to biologics  
🗑
Risk of infection with disease with IBD meds with   Immunomodulators/ biologics  
🗑
Biological therapies include   Remicade, humira, cimzia  
🗑
Aminosalicylates/ 5ASAs include   sulfasalazine  
🗑
ADR of Azothioprine (Imuran)   Pancreatitis, check LFTs/CBC every 90 days  
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Immunomodulators used in IBD   Azothioprine (Imuran)  
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MCC of small bowel obstruction   Previous surgery (adhesions)  
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Treatment for small bowel obstruction   NG tube, Bowel rest  
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50 y/o with history of atherosclerotic heart disease, hypoperfusion of the bowel vasculature   mesenteric ischemia  
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Secondary to removal of small intestines   Short bowel syndrome  
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If more than 50 cm of Ilium is resected patient needs   Monthly B-12 injection  
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Acute, painless, large volume maroon or BRB in pt. > 50 y/o   Diverticular hemorrhage  
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Treat diverticular hemorrhage with   Metronidazole & ciprofloxacin for 10 -14 days  
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Precedes most colon cancers   Adenomas  
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Hernia with a history of previous surgery   Incisional  
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Causes of lower GI bleed in patients < 50   Infectious colitis, IBD, fissures, hemorrhoids  
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Group A streptococcus pharyngitis presents with   Fever, absences of cough, tender cervical lymphadenopathy, & tonsiller exudates  
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Primary sclerosing cholangitis leads to   Cholestatic liver disease  
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SE of cimetidine (Tagamet)   HAs, Dizziness, skin rashes, loss of libido & gynocomastia  
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Secretin inhibits   Release of gastrin  
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