Brain Tumors
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| show | Schwannoma (most common tumor in neurofibromatosis type 2; they are usually bilateral; these patients are also at risk for meningiomas and ependymomas)
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| Frontal lobe tumor biopsy shows infiltrating cells with perinuclear halos and prominent delicate vasculature | show 🗑
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| Adult with "head fullness" and headaches when standing; T2-MRI shows lobulated mass that enhances with contrast and crosses the midline; immunostain is positive for glial fibrillary acidic protein | show 🗑
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| Biopsy of a solid cerebellar brain tumor from a child shows gray matter with abundant fibrillary material surrounded by a wheel-shaped configuration of differentiated cells | show 🗑
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| Tumor at cerebellopontine angle that stains positive for a protein that is 100% soluble in ammonium sulfate at neutral pH | show 🗑
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| Most likely brain tumor in a patient with bilateral renal cell carcinoma and pheochromocytoma | show 🗑
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| show | Meningioma (these arachnoid cell tumors are more common in females than males, and locations may include parasagittal, olfactory groove, or lesser wing of sphenoid; they may indent and compress the surface of the brain, but will not invade)
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| show | Pilocytic astrocytoma (the description is characteristic of Rosenthal fibers; this tumor would also stain positive for GFAP)
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| Resectable tumor often localized to CN VIII | show 🗑
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| show | Craniopharyngioma (most childhood brain tumors are below the tentorium cerebelli, while most adult primary brain tumors are above)
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| Most common cause of hypopituitarism in adults | show 🗑
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| show | Craniopharyngioma
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| show | Pilocytic astrocytoma
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| show | Cerebellar hemangioblastoma (the genetic disease is Von Hippel-Lindau and the tumor is producing erythropoietin)
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| show | Pilocytic astrocytoma
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| Most common primary malignant childhood brain tumor | show 🗑
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| 2nd most common primary childhood brain tumor | show 🗑
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| show | Meningioma
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| A child with hydrocephalus is determined to have a solid tumor in the cerebellar vermis; biopsy shows primitive small blue cells | show 🗑
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| show | Glioblastoma multiforme
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| show | Meningioma
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| show | Meningioma
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| show | Metastasis
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| Most frequent metastatic brain tumor primary location | show 🗑
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| Childhood brain tumor of cells lining the ventricles characterized by perivascular pseudorosettes and rod-shaped blepharoplasts (basal ciliary bodies) found near the nucleus | show 🗑
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| show | Craniopharyngioma (benign Rathke's pouch [surface ectoderm] tumor; do not confuse with pituitary adenoma)
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| show | Glioblastoma multiforme
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| Spindle cells concentrically arranged in a whorled pattern with basophilic laminated calcifications | show 🗑
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| show | Germinoma of the pineal gland (this is the most common tumor of the pineal gland; they produce beta-hCG that causes precocious puberty, hydrocephalus due to acqueductal compression, and Parinaud's syndrome due to compression of the midbrain tectal area)
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| Tumor is usually benign and may present as a hemorrhagic mass; it arises in the fourth ventricle in children (causing hydrocephalus) or the cauda equina in adults (causing syringomyelia) | show 🗑
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