Toxicology
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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| How are "screen positive" results confirmed | GC/MS (Gas Chromotography - Mass Spectrometry
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| When should you order a drug level | 1) suspician of noncompliance, individual patient variation, altered drug utilization, compensation for an altered physiological state, drug interactions
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| What are some means of direct removal of the toxin | emesis, whole bowel irrigation and stomach lavage, hemodialysis/hemoperfusion, activated charcoal
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| When do you need to give thiamine | with chronic or acute ethanol use
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| What do you give to reverse dysrhythmias and hypotension in patients who fail to respont to atropine, epinephrine, dopamine etc. following beta-blocker, or calcium channel blocker induced bradycardia adn hypotension | glucagon
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| what do you give to clear the body of methemoglobin | methylene blue
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| What adrenergic effect does Clonidine have | Alpha-2 adrenergic agonist
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| Hyperbaric oxygen is useful with what type of poisoning | CO
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| CaEDTA is an atidote for? | lead
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| 2,3 dimercaptosuccinic acid is an antidote for? | lead, arsenic, mercury
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| Naloxone reverses the effects of ? | opiates and propoxyphene
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| N-acetylcystein is thought to work by? | replenishing glutathione levels thus preventing liver damage following acetaminaphen overdose
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| What can you give with methanol poisoning | ethanol (favored by liver enzymes over methanol)
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| What does 4-methylpyrazole do? | specific inhibitor of alcohol dehydrogenase that has a higher affinity for the enzyme than methanol and ethylene glycol reducing production of toxic metabolites
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| What should you give to anemic patients taking isoniazid | pyridoxine
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| What should you give to reverse the effect of acute anticholinergic poisonings by binding to Ach | Physostigmine
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| what is a cholinesterase reactivator that reverses the inhibitory effect on the enzymes by organophosphate pesticides | pralidoxime
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| What is the specific benzodiazepine receptor antagonist that reverses the effects of both long and short acting benzodiazepines | flumazeni
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