Inflammatory Skin Disease
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| The cells that make up the epidermis are known as? | keratinocytes
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| what do langerhans cells do | process antigens
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| What do Merkel cells do? | act as mechanoreceptors
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| Dermatitis is often used to refer to ? | spongiotic dermatitis (also referred to clinically as eczema)
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| What is Acne Vulgaris | a disease of the follicle in where there is occlusion by keratin and sebum resulting in the overgrowth of propionibacterium acnes
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| What are the open and closed comedones called | blackheads and whiteheads
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| What is another term for vasculitis | leukocytoclastic vasculitis
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| What is the hallmark of vasculitis | palpable purpura
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| What are the pathological findings of vasculitis | infiltration of the vessel walls by neutrophils, endothelial swelling, fragmentation of neuclei of neutrophils (leukocytoclasis), erythrocyte extravasation, and sometimes thrombotic vessel occlusion, and fibrin depositition
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| What is Erythema Multiforme | eruption of macules, papules, vesicles, or bullae with a widespread distribution pattern
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| What is the name of erythema multiforme with mucous membrane involvement | Stevens Johnson Syndrome
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| What is the name of the Erythema Multiforme in which there can be extensive exfoliation of the skin | TEN toxic epidermal necrolysis
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| What are some triggering factors of Erythema Multiforme | herpes simplex, other infectious agents, and drugs
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| What are the three main microscopic findings of EM | vacuolar degeneration of the basilar layers, formation of eosinophilis, apoptotic bodies at the dermal-epidermal junction and at all levels of the epidermis
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| What is impetigo | a superficial bacterial infection caused by S. Aureus or S. pyrogenes
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| How do patients with impetigo present? | with erythematous papules that evolve into blisters or putules. These then rupture and produce the characteristic honey colored crusts
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| What is an example of a possible complication of impetigo | poststreptococcal glomerulonephritis
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| Where are there aggregates of neutrophils with impetigo | at the epidermal surface
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| Syphilis is a sexually transmitted disease caused by ? | Treponema pallidum
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| What is the name of the primary lesion in syphilis | chancre
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| Is the primary lesion of syphilis painful or painless? | painless
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| What are the skin lesions of secondary syphilis | condyloma lata, maculopapular eruptions that typically involve the palms and soles
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| What is the characteristic nodular or ulcerative lesion of the tertiary stage of syphilis | Gumma
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| What is the inflammatory cell found commonly at all stages of syphilis | plasma cells
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| Warts, or verrucae are cutaneous tumors induced by? | types of HPV
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| What are the four main kinds of warts? | Verruca Vulgaris, Vurruca Plantaris, Verruca plana, Condyloma acuminatum
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| What is the name of keratinocytes with pyknotic nuclei surrounding clear halos that may be aggregated near the epidermal surface? | Koilocytes
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| What are flesh colored dome shaped papules or small nodules with central keratotic cores | Molluscum Contagiosum
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| The causative agent in molluscum contagiosum is a member of what virus family | poxvirus
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| What are the most common herpesvirus infections due to? | herpes simplex 1 and 2, and varicella zoster virus
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| What are the most common superficial fungal infections caused by? | Dermatophytes, Candida albicans, adn the yeast pityrosporum
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| What is the hyphal form of pityrosporum | Malassezia furfur
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| What fungus is often a factor in diaper dermatitis | Candida
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| What is the cause of tinea versicolor | Malassezia furfur
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| What pathological changes do Dermatophytes and Candida infections often show | changes of spongiotic dermatitis
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| Where is the most common location for scabies lesions | fingerwebs, wrists, trunk, genitalia
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